ID A0AB34IZY0_PRYPA Unreviewed; 350 AA.
AC A0AB34IZY0;
DT 05-FEB-2025, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2025, sequence version 1.
DT 28-JAN-2026, entry version 5.
DE RecName: Full=BBSome complex member BBS5 PH domain-containing protein {ECO:0000259|SMART:SM00683};
GN ORFNames=AB1Y20_004677 {ECO:0000313|EMBL:KAL1508578.1};
OS Prymnesium parvum (Toxic golden alga).
OC Eukaryota; Haptista; Haptophyta; Prymnesiophyceae; Prymnesiales;
OC Prymnesiaceae; Prymnesium.
OX NCBI_TaxID=97485 {ECO:0000313|EMBL:KAL1508578.1, ECO:0000313|Proteomes:UP001515480};
RN [1] {ECO:0000313|EMBL:KAL1508578.1, ECO:0000313|Proteomes:UP001515480}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=12B1 {ECO:0000313|EMBL:KAL1508578.1,
RC ECO:0000313|Proteomes:UP001515480};
RX PubMed=39116217;
RA Fallon T.R., Shende V.V., Wierzbicki I.H., Pendleton A.L., Watervoot N.F.,
RA Auber R.P., Gonzalez D.J., Wisecaver J.H., Moore B.S.;
RT "Giant polyketide synthase enzymes in the biosynthesis of giant marine
RT polyether toxins.";
RL Science 385:671-678(2024).
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium membrane
CC {ECO:0000256|ARBA:ARBA00004309}. Cytoplasm, cytoskeleton, microtubule
CC organizing center, centrosome, centriolar satellite
CC {ECO:0000256|ARBA:ARBA00004607}.
CC -!- SIMILARITY: Belongs to the BBS5 family.
CC {ECO:0000256|ARBA:ARBA00005822}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAL1508578.1}.
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DR EMBL; JBGBPQ010000016; KAL1508578.1; -; Genomic_DNA.
DR AlphaFoldDB; A0AB34IZY0; -.
DR Proteomes; UP001515480; Unassembled WGS sequence.
DR GO; GO:0034464; C:BBSome; IEA:InterPro.
DR GO; GO:0034451; C:centriolar satellite; IEA:UniProtKB-SubCell.
DR GO; GO:0036064; C:ciliary basal body; IEA:TreeGrafter.
DR GO; GO:0060170; C:ciliary membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IEA:TreeGrafter.
DR GO; GO:0060271; P:cilium assembly; IEA:TreeGrafter.
DR InterPro; IPR006606; BBL5.
DR InterPro; IPR030804; BBS5/fem-3.
DR InterPro; IPR014003; BBS5_PH.
DR PANTHER; PTHR21351:SF0; BARDET-BIEDL SYNDROME 5 PROTEIN; 1.
DR PANTHER; PTHR21351; BARDET-BIEDL SYNDROME PROTEIN 5; 1.
DR Pfam; PF07289; BBL5; 1.
DR PIRSF; PIRSF010072; DUF1448; 1.
DR SMART; SM00683; DM16; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP001515480}.
FT DOMAIN 36..90
FT /note="BBSome complex member BBS5 PH"
FT /evidence="ECO:0000259|SMART:SM00683"
FT DOMAIN 166..220
FT /note="BBSome complex member BBS5 PH"
FT /evidence="ECO:0000259|SMART:SM00683"
SQ SEQUENCE 350 AA; 39635 MW; 5FA4E0E05B34FDEA CRC64;
MMSSGKKKPE DEESIWQDSD IRFDTHGSAL ELRPGEVRID SINSVEDTKG NNGEKGSLSI
TNLRLIWVCH RNPRVNLSIG YNAVASINIR SANSRLRGNT QALYVMTKFN KSRFEFVFTN
LVRQSPRLFT TVQAVYRAYD TSRLYRDLKL RGAIIKNKQL VLLPNEQVYN KVSGVWNLSS
DQGNLGTFFI SNVRVVWHAN LAENFNVSIP YMQMKVVRVR DSKFGQALVI ETNQRCGGYI
LGFRVDPVEQ LQVVFQEVLS LHQVFANTPI FGVDFSMEEK PPPLAELTVD RLQDDLEIVD
SDSSAHPHTA YFADRDNSKV ERDVVYSNEL GLAIEKLPEG VTAKSLWSVV
//
