ID A3Z1K3_9SYNE Unreviewed; 397 AA.
AC A3Z1K3;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 03-APR-2007, sequence version 1.
DT 18-JUN-2025, entry version 94.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=WH5701_10220 {ECO:0000313|EMBL:EAQ74005.1};
OS Synechococcus sp. WH 5701.
OC Bacteria; Bacillati; Cyanobacteriota; Cyanophyceae; Synechococcales;
OC Synechococcaceae; Synechococcus.
OX NCBI_TaxID=69042 {ECO:0000313|EMBL:EAQ74005.1, ECO:0000313|Proteomes:UP000002935};
RN [1] {ECO:0000313|EMBL:EAQ74005.1, ECO:0000313|Proteomes:UP000002935}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WH5701 {ECO:0000313|Proteomes:UP000002935};
RA Scanlan D., Ferriera S., Johnson J., Kravitz S., Halpern A., Remington K.,
RA Beeson K., Tran B., Rogers Y.-H., Friedman R., Venter J.C.;
RL Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAQ74005.1}.
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DR EMBL; AANO01000011; EAQ74005.1; -; Genomic_DNA.
DR AlphaFoldDB; A3Z1K3; -.
DR eggNOG; COG2205; Bacteria.
DR HOGENOM; CLU_723030_0_0_3; -.
DR Proteomes; UP000002935; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0048511; P:rhythmic process; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR FunFam; 3.30.565.10:FF:000006; Sensor histidine kinase WalK; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P_dom.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR011649; KaiB_domain.
DR InterPro; IPR050736; Sensor_HK_Regulatory.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR NCBIfam; NF006800; PRK09303.1; 1.
DR PANTHER; PTHR43711:SF26; SENSOR HISTIDINE KINASE RCSC; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF07689; KaiB; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM01248; KaiB; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EAQ74005.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000002935};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EAQ74005.1};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 174..387
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 397 AA; 44019 MW; 32329468868CB0CF CRC64;
MMPTISPAAK VPEAGKTDPG TTAPGPLPAR RRALKLLLVA APHHLASADL GGVLNYLETC
DCGFDVALEL ANPALRPELL ELHRLVATPA LVKLEPPPRQ VLAGNAVLDQ LKGWLPRWQQ
LEMVSDLGMS LRPAEMDGSR SQRELQLEDQ VLVLRQENET LIERLRVQER LLRMVAHELR
TPLTAAKLAL QSLQLGHINN TRCRDVLDRR LDDIEHLSKD LLEVGTTRWE ALFNPQRLDL
APVAAEAILE LEKLWVGRTL RLITDIPADL PDVFADQRRM RQVLLNLLEN ALKYTPDSGE
VTLSLLHRTS QWVQVSVCDT GPGIPRGEQE RIFLERVRLP QTSGTTSGFG VGLSVCRRIV
EVHGGRIWVV SEPGEGACFH FTVPVWSGQN SPSQASP
//
