ID A7MG84_CROS8 Unreviewed; 1015 AA.
AC A7MG84;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 02-APR-2025, entry version 92.
DE RecName: Full=Autotransporter domain-containing protein {ECO:0000259|PROSITE:PS51208};
GN OrderedLocusNames=ESA_03404 {ECO:0000313|EMBL:ABU78622.1};
OS Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii).
OC Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
OC Enterobacterales; Enterobacteriaceae; Cronobacter.
OX NCBI_TaxID=290339 {ECO:0000313|EMBL:ABU78622.1, ECO:0000313|Proteomes:UP000000260};
RN [1] {ECO:0000313|EMBL:ABU78622.1, ECO:0000313|Proteomes:UP000000260}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-894 {ECO:0000313|EMBL:ABU78622.1,
RC ECO:0000313|Proteomes:UP000000260};
RX PubMed=20221447; DOI=10.1371/journal.pone.0009556;
RA Kucerova E., Clifton S.W., Xia X.Q., Long F., Porwollik S., Fulton L.,
RA Fronick C., Minx P., Kyung K., Warren W., Fulton R., Feng D., Wollam A.,
RA Shah N., Bhonagiri V., Nash W.E., Hallsworth-Pepin K., Wilson R.K.,
RA McClelland M., Forsythe S.J.;
RT "Genome sequence of Cronobacter sakazakii BAA-894 and comparative genomic
RT hybridization analysis with other Cronobacter species.";
RL PLoS ONE 5:E9556-E9556(2010).
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR EMBL; CP000783; ABU78622.1; -; Genomic_DNA.
DR RefSeq; WP_012125859.1; NC_009778.1.
DR AlphaFoldDB; A7MG84; -.
DR MEROPS; S08.094; -.
DR KEGG; esa:ESA_03404; -.
DR PATRIC; fig|290339.8.peg.3023; -.
DR HOGENOM; CLU_005887_2_0_6; -.
DR Proteomes; UP000000260; Chromosome.
DR GO; GO:0019867; C:outer membrane; IEA:InterPro.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd04848; Peptidases_S8_Autotransporter_serine_protease_like; 1.
DR Gene3D; 2.40.128.130; Autotransporter beta-domain; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR005546; Autotransporte_beta.
DR InterPro; IPR036709; Autotransporte_beta_dom_sf.
DR InterPro; IPR013425; Autotrns_rpt.
DR InterPro; IPR006315; OM_autotransptr_brl_dom.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR022398; Peptidase_S8_His-AS.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR050131; Peptidase_S8_subtilisin-like.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034061; Peptidases_S8_Autotransporter.
DR NCBIfam; TIGR01414; autotrans_barl; 1.
DR NCBIfam; TIGR02601; autotrns_rpt; 1.
DR PANTHER; PTHR43806:SF11; CEREVISIN-RELATED; 1.
DR PANTHER; PTHR43806; PEPTIDASE S8; 1.
DR Pfam; PF03797; Autotransporter; 1.
DR Pfam; PF12951; PATR; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SMART; SM00869; Autotransporter; 1.
DR SUPFAM; SSF103515; Autotransporter; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51208; AUTOTRANSPORTER; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00137; SUBTILASE_HIS; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000000260};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 738..1015
FT /note="Autotransporter"
FT /evidence="ECO:0000259|PROSITE:PS51208"
FT ACT_SITE 68
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 125
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 346
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 1015 AA; 106013 MW; 153AA97550F69A64 CRC64;
MSAVAIALGL AGIGQAAASN YIEQGKAGDA ASWRSSEFNA EWGLGAIHAD EAYAAGYTGK
GIKLGIFDQP VYAKHPEFSG TDKVINLVTE GIREYTDPYI PVKKGDPFRY DGTPSVDSDG
ELGAHGTHVG GIAAGSRDGG PMHGVAFNAQ IISAENGDPG PEDGIILGND GAVYEAGWHA
LMDSGARIIN NSWGIGITEK FDQGGKDPAY PHFTVSDAQA QFNQIKQILG TKPGGAYQGA
IDAARSGIVT IFAAGNDYNL NNPDAMAGLA YFVPDIAPNW LSVASVMKDP ASANSVPYTI
STFSSRCGYT ASFCVSAPGS RIYSSVIEGN SLETLTTDYA NYSGTSMAAP HVAGSVAVLM
ERFPYMTGEQ IAQVLKTTTV DMGDPGIDAL YGWGMIDLSK AIHGPGMFYT VEDIPEEFRV
PDPDGVAYGS SQFIADIPGI GEEVEAGTKL ARTCSDIQCA MDVWSNDISG HGGLTKQGAG
ALWLTGTSTY SGPTLVNDGL LVVNGSVTSD VTVQQQGVLA GNGTVGSLTA ARGGTVAPGN
SIGTLNVNGD VTFQPGSRYA VEVSPDGRSD VINATGAIAL NGGEVAVSLE NSSNLLSLAE
VRSLLGQQYN ILSAADGITG QFDSVAPDYL FLGTSLGYTG GQVTLDVARN DTTFASIADT
ANGRAVAGAL ETLGAGNPLY ESLLSTGSVA QARQAFRQLG GQIHADIASA QINDSRYLRD
TLNERLRQAE GLTSVSPVAA DDGGAWAKLL GAWDHASGDE SATGYQASTY GVLLGLDSAY
ADDWRMGVAT GYTRTSLDGG YGSSADSDNY HLAVYGGKQL GELALRAGAG YTWHRFDTSR
SVRFGSQSDR ADAKYNARTE QFFAEAGYQL AAGMVNVEPF ANVSYVNFEN NRINEQGGAT
ALHGDKQHTD ATFSTLGLRS GLEWDATAET TVALRGEVGW QHQYGELDRA TGLKFRGSST
PFVTNSVSAS RDGTVLKASA EVAVNRNAHL SLGYSGLISD NYQDNSVNAG FSWNF
//
