ID A7MH61_CROS8 Unreviewed; 924 AA.
AC A7MH61;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 02-APR-2025, entry version 93.
DE RecName: Full=Autotransporter domain-containing protein {ECO:0000259|PROSITE:PS51208};
GN OrderedLocusNames=ESA_00894 {ECO:0000313|EMBL:ABU76164.1};
OS Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii).
OC Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
OC Enterobacterales; Enterobacteriaceae; Cronobacter.
OX NCBI_TaxID=290339 {ECO:0000313|EMBL:ABU76164.1, ECO:0000313|Proteomes:UP000000260};
RN [1] {ECO:0000313|EMBL:ABU76164.1, ECO:0000313|Proteomes:UP000000260}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-894 {ECO:0000313|EMBL:ABU76164.1,
RC ECO:0000313|Proteomes:UP000000260};
RX PubMed=20221447; DOI=10.1371/journal.pone.0009556;
RA Kucerova E., Clifton S.W., Xia X.Q., Long F., Porwollik S., Fulton L.,
RA Fronick C., Minx P., Kyung K., Warren W., Fulton R., Feng D., Wollam A.,
RA Shah N., Bhonagiri V., Nash W.E., Hallsworth-Pepin K., Wilson R.K.,
RA McClelland M., Forsythe S.J.;
RT "Genome sequence of Cronobacter sakazakii BAA-894 and comparative genomic
RT hybridization analysis with other Cronobacter species.";
RL PLoS ONE 5:E9556-E9556(2010).
CC -!- SIMILARITY: Belongs to the peptidase S8 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01240}.
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DR EMBL; CP000783; ABU76164.1; -; Genomic_DNA.
DR AlphaFoldDB; A7MH61; -.
DR MEROPS; S08.160; -.
DR KEGG; esa:ESA_00894; -.
DR PATRIC; fig|290339.8.peg.794; -.
DR HOGENOM; CLU_005887_0_0_6; -.
DR Proteomes; UP000000260; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:TreeGrafter.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016485; P:protein processing; IEA:TreeGrafter.
DR CDD; cd04848; Peptidases_S8_Autotransporter_serine_protease_like; 1.
DR Gene3D; 2.40.128.130; Autotransporter beta-domain; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR005546; Autotransporte_beta.
DR InterPro; IPR036709; Autotransporte_beta_dom_sf.
DR InterPro; IPR013425; Autotrns_rpt.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034061; Peptidases_S8_Autotransporter.
DR NCBIfam; TIGR02601; autotrns_rpt; 1.
DR PANTHER; PTHR42884:SF14; NEUROENDOCRINE CONVERTASE 1; 1.
DR PANTHER; PTHR42884; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED; 1.
DR Pfam; PF03797; Autotransporter; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SMART; SM00869; Autotransporter; 1.
DR SUPFAM; SSF103515; Autotransporter; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51208; AUTOTRANSPORTER; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000000260};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..32
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 33..924
FT /note="Autotransporter domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002710995"
FT DOMAIN 645..924
FT /note="Autotransporter"
FT /evidence="ECO:0000259|PROSITE:PS51208"
FT ACT_SITE 87
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 123
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 303
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 924 AA; 96615 MW; 953EA1B9184DBD12 CRC64;
MPTDVSLGKG TFLTTGKVIP LIILACSGAA SASAKKNADD TFTYVPSVAA ADVVTRTNYN
RPLFITSAAT ARAAGINGAG IKVGVADTGI LTTHPALLGV VKGTLNYVDP SANNLSVGDV
RGHGTMVAQT LAGRATGLFT GGTAPGATLI SARIIPDVAN TRQSLNFGQI NYDLARAGAK
IINNSWGIPD WNPTSTATTT YFVNAWKPFI SSYNGLIVFA SGNDGAANPV GVAKLPSLAP
ASGLDKGWLV ATAVDTFNPS YIASYANRCG VMKNSCLAAP GSVYVQSTDS TGKPVLRLVS
GTSFAAPQVS GVAAMVWQKY PYFTNDLVRQ TVLGTATDIG APGVDAVFGY GLLNAAKAIN
GPAKFNWGTV SVAFNSYTST WSNAISGSGG LIKGGTGKLV LTQDASYTGT TQVLGGSLSS
AKSLASAVNI GRAGTLDVRT VKGNVDNSGF VLLRDGKTRF MTNYTQRTTG GLAFMLGSTL
DVAGRATLAG NLHLLGVPAG YITQARQPVV NAGAVSGKFS RFTQSAGVFL TGSLGYSTKQ
VWLNIKRLQV TQTKVASTSA ATQSAAVRLE QAFTQLDKQV ATGVAVRASS FASAAGELQH
ISNNTSARAA LESLSGQLPA ATAALTWQAI NVNQRSSANH INALLDAPQS RSWSDTLSWN
GSLGRSGYSP VSYSMKGWVT GQDRFIDEHT FIGTSLSRTD TFSALSSGGE RNTGTLSEAA
LYGGKIYGGY YLTGRLASGY YDGQQRRMLW LGSRSERVSS RQSGSWMSLG SETGYRFNVD
GLAVTPFIDT QYITLKQDAF SEKSGSGFGL RADNQTTTRW QAGAGLRAAY TFDLQTHGRL
DLSFQTHLQR ALSQDEGRYQ ASFTGVDQPV PLHGVTAPEK TLTSAVSLGW QVNPALNLNL
TGEQETSDGR NSNRSVMAGV SLSF
//
