ID A7TH76_VANPO Unreviewed; 577 AA.
AC A7TH76;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 10-JUN-2026, entry version 59.
DE RecName: Full=Mitotic check point protein BFA1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=Kpol_1013p28 {ECO:0000313|EMBL:EDO18357.1};
OS Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX NCBI_TaxID=436907 {ECO:0000313|EMBL:EDO18357.1, ECO:0000313|Proteomes:UP000000267};
RN [1] {ECO:0000313|EMBL:EDO18357.1, ECO:0000313|Proteomes:UP000000267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 /
RC NRRL Y-8283 / UCD 57-17 {ECO:0000313|Proteomes:UP000000267};
RX PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT species descended from a whole-genome duplication.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
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DR EMBL; DS480390; EDO18357.1; -; Genomic_DNA.
DR RefSeq; XP_001646215.1; XM_001646165.1.
DR AlphaFoldDB; A7TH76; -.
DR FunCoup; A7TH76; 357.
DR STRING; 436907.A7TH76; -.
DR GeneID; 5546640; -.
DR KEGG; vpo:Kpol_1013p28; -.
DR eggNOG; ENOG502R6H5; Eukaryota.
DR HOGENOM; CLU_037140_0_0_1; -.
DR InParanoid; A7TH76; -.
DR OMA; QEIDHNT; -.
DR OrthoDB; 19159at2759; -.
DR PhylomeDB; A7TH76; -.
DR Proteomes; UP000000267; Unassembled WGS sequence.
DR GO; GO:1990334; C:Bfa1-Bub2 complex; IEA:EnsemblFungi.
DR GO; GO:0044732; C:mitotic spindle pole body; IEA:TreeGrafter.
DR GO; GO:0005092; F:GDP-dissociation inhibitor activity; IEA:EnsemblFungi.
DR GO; GO:0005096; F:GTPase activator activity; IEA:EnsemblFungi.
DR GO; GO:0031578; P:mitotic spindle orientation checkpoint signaling; IEA:EnsemblFungi.
DR InterPro; IPR034586; Bfa1/Byr4.
DR PANTHER; PTHR35140; MITOTIC CHECK POINT PROTEIN BFA1; 1.
DR PANTHER; PTHR35140:SF1; MITOTIC CHECK POINT PROTEIN BFA1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000267}.
FT REGION 27..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 177..205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 474..512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 180..192
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 485..494
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 495..504
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 577 AA; 67299 MW; D171B5063C163F78 CRC64;
MSIRPMNFAE FPETSFEDLD TTLNKVSKEE NENGNNNGNV KQSSPLRQAF MNNTPSITAS
SEGTVFSNML DKYSSGSKTD DEGQHRMQLQ EQGQLGPFED DEEDFLNDFE EFQNKKDDFD
EALKLHFQLR GQSSPNTNKD GLQYRTDNVI GKLSDRFERN FSISNRLKQP RSMMDIKSNG
RYNLANSRSS GSLRERSNNG LKNKKSMPLL SRFQPTIEEI DDNSTVDSDV YDEESLPRND
RYDQRNAQFL NNFQEEDELT EDEDFKLDEG LIKPQFLNSR RQSVVPMRLS PSEYDIVADD
TLLTPRLHKR SKDWNGRSKL NSFKERKIRN YPSLSKIKTI KQEIDHNTPI KKGRMYYNPQ
TMMWEGNEKI LEKFQSVDSN DKKPLLIRTK SQLSPKNKDL KLRKSTTQLT NPSREEFRNR
PSVNNPRIVG NMMFDDVNLR WVSTSREDEE HDPFKNIPEL KSLSLKQARY KSAPSNDVNS
PFLRSKSHQI KRKSNNNNNT INSRFLSTGH NNNTHEVEDE EIFELNAKML EKFYHEEHKW
YKKIGSWIIL SSDGKANKKS NNYKYEIRSM VMNSSRG
//
