ID A9UP59_MONBE Unreviewed; 480 AA.
AC A9UP59;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 08-OCT-2025, entry version 54.
DE RecName: Full=Pru domain-containing protein {ECO:0000259|PROSITE:PS51917};
GN ORFNames=MONBRDRAFT_30775 {ECO:0000313|EMBL:EDQ92817.1};
OS Monosiga brevicollis (Choanoflagellate).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ92817.1, ECO:0000313|Proteomes:UP000001357};
RN [1] {ECO:0000313|EMBL:EDQ92817.1, ECO:0000313|Proteomes:UP000001357}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX PubMed=18273011; DOI=10.1038/nature06617;
RG JGI Sequencing;
RA King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT metazoans.";
RL Nature 451:783-788(2008).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; CH991543; EDQ92817.1; -; Genomic_DNA.
DR RefSeq; XP_001742579.1; XM_001742527.1.
DR AlphaFoldDB; A9UP59; -.
DR STRING; 81824.A9UP59; -.
DR GeneID; 5887541; -.
DR KEGG; mbr:MONBRDRAFT_30775; -.
DR eggNOG; KOG3037; Eukaryota.
DR InParanoid; A9UP59; -.
DR Proteomes; UP000001357; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008541; C:proteasome regulatory particle, lid subcomplex; IBA:GO_Central.
DR GO; GO:0061133; F:endopeptidase activator activity; IBA:GO_Central.
DR GO; GO:0070628; F:proteasome binding; IBA:GO_Central.
DR FunFam; 1.10.2020.20:FF:000013; -; 1.
DR Gene3D; 1.10.2020.20; -; 1.
DR Gene3D; 2.30.29.70; Proteasomal ubiquitin receptor Rpn13/ADRM1; 1.
DR InterPro; IPR006773; Rpn13/ADRM1.
DR InterPro; IPR044868; Rpn13/ADRM1_Pru.
DR InterPro; IPR038633; Rpn13/ADRM1_Pru_sf.
DR InterPro; IPR032368; RPN13_DEUBAD.
DR InterPro; IPR038108; RPN13_DEUBAD_sf.
DR PANTHER; PTHR12225; ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN; 1.
DR PANTHER; PTHR12225:SF0; PROTEASOMAL UBIQUITIN RECEPTOR ADRM1; 1.
DR Pfam; PF04683; Rpn13_ADRM1_Pru; 1.
DR Pfam; PF16550; RPN13_C; 1.
DR PROSITE; PS51917; PRU; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW Reference proteome {ECO:0000313|Proteomes:UP000001357}.
FT DOMAIN 65..178
FT /note="Pru"
FT /evidence="ECO:0000259|PROSITE:PS51917"
FT REGION 209..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 218..234
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 480 AA; 53819 MW; 7DA6A1E590809F4F CRC64;
MLQMLKLAPH EQQGFQWQSW HVTNIRPCCL AQTAAESFDL RTFEDTSTMS LFANSTPGGR
GMARPANANL FEFKAGRMTQ EGNTVTAVPG KGLVFLKRDG DLLMWHYKSR DSGREEEEPI
VLFPGEQTFQ LCKSAPASSR VYYLKFSGGR RDFFWMQSPD AAGDALICQR VNRLIDGGSI
DEEGVNDHPM GVDASEEQQA IMQMLRDDVS TPGHASGAAQ RPPAAPTRQR AQQRSGNAEA
GGEDQPLSQD NMQGLVQNFA REMMVSQATS LTDVLSASNV EPLLDNPETV QRLLAHLPDG
DNASVGNIRS TLRSPQYAQH EAPLQHGKKQ SYARLHKENN NNKVCNALMH GPLRRPTSED
LVTHSDSNIL SLFPHVTREL PDLHYDVVLH LSLSLSFVFR LFLSLFVLFR LSLSLSVLSL
SYLHPLLLES VFLCELFEVS AFFPVSRRRT TGIILRGSRR TIRWHSANRF RFSYHCQKLH
//
