ID B5DQN2_DROPS Unreviewed; 795 AA.
AC B5DQN2; A0A6I8V1E1;
DT 14-OCT-2008, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 2.
DT 28-JAN-2026, entry version 95.
DE SubName: Full=Collagen alpha-1(XVIII) chain isoform X16 {ECO:0000313|RefSeq:XP_002134828.2};
GN Name=Mp {ECO:0000313|RefSeq:XP_002134828.2};
OS Drosophila pseudoobscura pseudoobscura (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=46245 {ECO:0000313|Proteomes:UP000001819, ECO:0000313|RefSeq:XP_002134828.2};
RN [1] {ECO:0000313|RefSeq:XP_002134828.2}
RP IDENTIFICATION.
RC STRAIN=MV-25-SWS-2005 {ECO:0000313|RefSeq:XP_002134828.2};
RC TISSUE=Whole body {ECO:0000313|RefSeq:XP_002134828.2};
RG RefSeq;
RL Submitted (AUG-2025) to UniProtKB.
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DR RefSeq; XP_002134828.2; XM_002134792.4.
DR AlphaFoldDB; B5DQN2; -.
DR GeneID; 6900437; -.
DR KEGG; dpo:6900437; -.
DR eggNOG; KOG3544; Eukaryota.
DR eggNOG; KOG3546; Eukaryota.
DR HOGENOM; CLU_014222_0_0_1; -.
DR Proteomes; UP000001819; Chromosome X.
DR Bgee; FBgn0244988; Expressed in insect adult head and 1 other cell type or tissue.
DR ExpressionAtlas; B5DQN2; baseline.
DR GO; GO:0005594; C:collagen type IX trimer; IEA:TreeGrafter.
DR GO; GO:0005615; C:extracellular space; IEA:TreeGrafter.
DR GO; GO:0030020; F:extracellular matrix structural constituent conferring tensile strength; IEA:TreeGrafter.
DR GO; GO:0030198; P:extracellular matrix organization; IEA:TreeGrafter.
DR CDD; cd00247; Endostatin-like; 1.
DR FunFam; 3.10.100.10:FF:000048; Multiplexin collagen isoform Ap3; 1.
DR FunFam; 3.40.1620.70:FF:000001; Multiplexin collagen isoform Ap3; 1.
DR Gene3D; 3.40.1620.70; -; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR050149; Collagen_superfamily.
DR InterPro; IPR010515; Collagenase_NC10/endostatin.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR045463; XV/XVIII_trimerization_dom.
DR PANTHER; PTHR24023; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24023:SF1116; MACROPHAGE RECEPTOR WITH COLLAGENOUS STRUCTURE; 1.
DR Pfam; PF01391; Collagen; 3.
DR Pfam; PF20010; Collagen_trimer; 1.
DR Pfam; PF06482; Endostatin; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
PE 4: Predicted;
KW Collagen {ECO:0000256|ARBA:ARBA00023119,
KW ECO:0000313|RefSeq:XP_002134828.2};
KW Reference proteome {ECO:0000313|Proteomes:UP000001819}.
FT DOMAIN 483..531
FT /note="Collagen type XV/XVIII trimerization"
FT /evidence="ECO:0000259|Pfam:PF20010"
FT DOMAIN 581..746
FT /note="Collagenase NC10/endostatin"
FT /evidence="ECO:0000259|Pfam:PF06482"
FT REGION 56..110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 148..456
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 753..778
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 69..90
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 94..103
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 200..211
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 220..233
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 239..256
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 338..350
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..375
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 402..413
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 795 AA; 82781 MW; 30269A5081FBD563 CRC64;
MAMVISTRAK LVITALILFF LLGIVLVTGS TKGWFNPNRY NGERVAARIQ ATDIFDASGM
QPPGQTQYTH ERPYRGIKGE KGERGPKGDS IRGPPGPPGP PGPKGEAAAY PPFVETTSAG
AKYTGECTCN ASDILEAIKD NESLRETLRG APGTQGKDGK PGTPGHTGAT GVPGARGARG
SEGAQGQKGE PGVDGLPGVA GPPGPAGPPG LPENYDESLM VNSMGTFRGT TQPGPKGVSG
EKGEAGQKGE RGDPGHKGAH GSNGAKGEPG EPGTPGLPGL PGQAGQPGGL EGLSANGTKG
EKGEKGMRGR RGGTGSTGPI GPPGKPGAMG DIGHSGRPGM TGPKGEMGPK GPKGDTGGRE
GPKGDKGDTG QDGRDGLPGP PGLPASGGGD GDSSGVQYIP MAGPPGPPGP PGLPGLSITG
PKGEPGMDSR SFFGDASYYG RPEAPRQPGH SHKHEEALGP AVGEEPYFSA SSSNINMKIV
PGAVTFQNID EMTKKSALNP PGTLAYITEE EALLVRVNKG WQYIALGTLV PIATPAPPTT
VAPSMRFDLQ SKNLLNSPPP PLNTPTFTTA PEYETWYPRM LRVAALNEPS VGDLQGIRGA
DFACYRQGRR AGLLGTFKAF LSSRVQNLDS IVRPADRDLP VVNTRGDVLF NSWKGIFNGQ
GGFFSQAPRI YSFSGKNVMT DPLWPLKMVW HGSLPNGERS MDTYCDAWHS SAHDKSGYAS
DLAGHKLLEQ KRQPCDGKLI VLCVEALSQD RKRKKRDASD SHSYGHSHSR GPSRSQNLEF
RTAEEYAAHL DDLLL
//
