ID C2KVU0_9FIRM Unreviewed; 665 AA.
AC C2KVU0;
DT 16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT 16-JUN-2009, sequence version 1.
DT 08-OCT-2025, entry version 76.
DE SubName: Full=Selenocysteine-specific translation elongation factor {ECO:0000313|EMBL:EEJ52114.1};
GN Name=selB {ECO:0000313|EMBL:EEJ52114.1};
GN ORFNames=HMPREF6123_0609 {ECO:0000313|EMBL:EEJ52114.1};
OS Oribacterium sinus F0268.
OC Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
OC Lachnospiraceae; Oribacterium.
OX NCBI_TaxID=585501 {ECO:0000313|EMBL:EEJ52114.1, ECO:0000313|Proteomes:UP000004121};
RN [1] {ECO:0000313|EMBL:EEJ52114.1, ECO:0000313|Proteomes:UP000004121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0268 {ECO:0000313|EMBL:EEJ52114.1,
RC ECO:0000313|Proteomes:UP000004121};
RA Qin X., Bachman B., Battles P., Bell A., Bess C., Bickham C., Chaboub L.,
RA Chen D., Coyle M., Deiros D.R., Dinh H., Forbes L., Fowler G.,
RA Francisco L., Fu Q., Gubbala S., Hale W., Han Y., Hemphill L.,
RA Highlander S.K., Hirani K., Hogues M., Jackson L., Jakkamsetti A.,
RA Javaid M., Jiang H., Korchina V., Kovar C., Lara F., Lee S., Mata R.,
RA Mathew T., Moen C., Morales K., Munidasa M., Nazareth L., Ngo R.,
RA Nguyen L., Okwuonu G., Ongeri F., Patil S., Petrosino J., Pham C., Pham P.,
RA Pu L.-L., Puazo M., Raj R., Reid J., Rouhana J., Saada N., Shang Y.,
RA Simmons D., Thornton R., Warren J., Weissenberger G., Zhang J., Zhang L.,
RA Zhou C., Zhu D., Muzny D., Worley K., Gibbs R.;
RL Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEJ52114.1}.
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DR EMBL; ACKX01000063; EEJ52114.1; -; Genomic_DNA.
DR RefSeq; WP_007156073.1; NZ_GG668533.1.
DR AlphaFoldDB; C2KVU0; -.
DR STRING; 585501.HMPREF6123_0609; -.
DR eggNOG; COG3276; Bacteria.
DR HOGENOM; CLU_023030_3_0_9; -.
DR InParanoid; C2KVU0; -.
DR OrthoDB; 9804504at2; -.
DR Proteomes; UP000004121; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR CDD; cd15491; selB_III; 1.
DR Gene3D; 1.10.10.2770; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR PANTHER; PTHR43721:SF11; SELENOCYSTEINE-SPECIFIC ELONGATION FACTOR; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:EEJ52114.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000004121}.
FT DOMAIN 24..199
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..14
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 665 AA; 75681 MW; 5023A31025E5DE0D CRC64;
MESTQNPDVQ QLSNVEKPEG KKESKHLIIG TAGHIDHGKT ALIKALTGYD ADRLEEEKKR
GMTIELGFTS LSLPDGQKIG IVDTPGHEKF VKTMVAGAVG MDLVMVVISA KEGIMPQTRE
HLSILSLLGI KNFIICLTMI DLVSPEEVEQ RKMEITEYLE KQFSFTVPIF PLSSYTREGI
PALTNYLSTL HEFIQGKPEQ GIFRMFVDRV FSIAGAGTIL TGTAMSGRIE LKKEYALYPK
NLPVKVRNLQ VHGKDSDFAV GGERVAVNLS SIDKSLCQKG DVLAEKDLLY PSSLLDCRVQ
VDNALEQSIK NNRKLELLLG TRHVLCKLVC LEGEEIPNKS SALVQLQCEE PVVALSGDRF
ILRDESQKLS IGGGKVIDPL PRGRHRRGRF QTERLRSLED ADEGSLLQNF FHKKKGIFLA
LSAIRKAFPG YGNIENTLRD KEEKGELISI LLQGEKYLIP GEDLEEKEKQ IQYYMKDFYQ
RNPYKIGEKT SVLYSRFFSS YNRNIYKALL EYWREKEIFR ISHDILAIKD YKMKKDEKYT
KIANTLITLM QKAKFSFPKI TEPLWSKEEE KILLDIVACL EEKGTLVQLE GEYYTLGNLF
SKLKEFTLEK LQSKGEITVE DLREEFSLSR KNSKLFFKAC DRLHITKDNG FESARKPYPK
LDETE
//
