ID C3XE46_9HELI Unreviewed; 671 AA.
AC C3XE46;
DT 16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 2.
DT 28-JAN-2026, entry version 54.
DE RecName: Full=CN hydrolase domain-containing protein {ECO:0000259|PROSITE:PS50263};
GN ORFNames=HRAG_00342 {ECO:0000313|EMBL:EEO23285.2};
OS Helicobacter bilis ATCC 43879.
OC Bacteria; Pseudomonadati; Campylobacterota; Epsilonproteobacteria;
OC Campylobacterales; Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=613026 {ECO:0000313|EMBL:EEO23285.2, ECO:0000313|Proteomes:UP000005085};
RN [1] {ECO:0000313|EMBL:EEO23285.2, ECO:0000313|Proteomes:UP000005085}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43879 {ECO:0000313|EMBL:EEO23285.2,
RC ECO:0000313|Proteomes:UP000005085};
RX PubMed=25212613;
RA Shen Z., Sheh A., Young S.K., Abouelliel A., Ward D.V., Earl A.M.,
RA Fox J.G.;
RT "Draft genome sequences of six enterohepatic helicobacter species isolated
RT from humans and one from rhesus macaques.";
RL Genome Announc. 2:e00857-e00814(2014).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC -!- SIMILARITY: Belongs to the CN hydrolase family. Apolipoprotein N-
CC acyltransferase subfamily. {ECO:0000256|ARBA:ARBA00010065}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEO23285.2}.
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DR EMBL; ACDN02000007; EEO23285.2; -; Genomic_DNA.
DR RefSeq; WP_020995500.1; NZ_KI392032.1.
DR AlphaFoldDB; C3XE46; -.
DR eggNOG; COG0815; Bacteria.
DR HOGENOM; CLU_409264_0_0_7; -.
DR OrthoDB; 9804277at2; -.
DR Proteomes; UP000005085; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016410; F:N-acyltransferase activity; IEA:InterPro.
DR GO; GO:0042158; P:lipoprotein biosynthetic process; IEA:InterPro.
DR Gene3D; 3.60.110.10; Carbon-nitrogen hydrolase; 1.
DR InterPro; IPR004563; Apolipo_AcylTrfase.
DR InterPro; IPR003010; C-N_Hydrolase.
DR InterPro; IPR036526; C-N_Hydrolase_sf.
DR InterPro; IPR059109; Lnt_membrane_dom.
DR PANTHER; PTHR38686; APOLIPOPROTEIN N-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR38686:SF1; APOLIPOPROTEIN N-ACYLTRANSFERASE; 1.
DR Pfam; PF26365; ApoNAT_membrane; 1.
DR Pfam; PF00795; CN_hydrolase; 1.
DR SUPFAM; SSF56317; Carbon-nitrogen hydrolase; 1.
DR PROSITE; PS50263; CN_HYDROLASE; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005085};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 37..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 117..140
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 160..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 187..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 237..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 299..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 345..671
FT /note="CN hydrolase"
FT /evidence="ECO:0000259|PROSITE:PS50263"
SQ SEQUENCE 671 AA; 77467 MW; 090D4D17526769E5 CRC64;
MTQNSQQHTN NTIYNFLKTF FITCKTKHFL VLRHATTYLH TTSLLQVLFC YPFYIFSPLL
LSRIMQGGVT QAIPTQTLKK QTRFKKILHK AMVGICFGFL FWLPFWCFIL ESILPPILYG
IFCVFLVAFM LYICAILIRL KVESHNNTLS KKPLIHAKKY VVDTALPFFL VFIILCVGIF
SLLHKNTYIG VSLCYPLSIA IFLFMPRMYR FWFGFFVGIF GFYWMTLSFR FEGLSLLIPF
IVICVGIIYG LFFWILLYFQ NLVWRIIAMA SLFILHPLDF NWLNIAYLSS YSVFEASLLS
LLCVAFACYF IITKSALQLL APLLLLMSLD YDMTRQDPKL QAKIIETQYK QDMRWEEENR
ESIIANNLEA IQQAIDEGYP LVILPETSFP LILNTQTELY HKLLDLSRHI TIVTGAMRVQ
NIELGKFLDS SHCDTNNTDL TQNLDFNACH VEQSEISKSL ESSKDISAMA QNDNKQNLNS
KTNSKTTYNK IDSINTHKKH SSLFTLDTLQ QREKTLDSDS IESSYINTPT KDFGYYNSVY
IFSKGYSLIA DKNALVPFGE TLPFNAILSP IFEEIFGDSF GFNKGDEIIS FITQGLHVAI
ANCYEGTMEL PYNTGAKYIL MLSNNAWFYP STQHFMQQMI VKYYARSFQT FIYHSTNYTP
KAIITPNNGR D
//
