ID D3DJX9_HYDTT Unreviewed; 311 AA.
AC D3DJX9;
DT 23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 23-MAR-2010, sequence version 1.
DT 02-APR-2025, entry version 83.
DE RecName: Full=Sulfur carrier protein FdhD {ECO:0000256|HAMAP-Rule:MF_00187};
GN Name=fdsC {ECO:0000313|EMBL:BAI70131.1};
GN Synonyms=fdhD {ECO:0000256|HAMAP-Rule:MF_00187};
GN OrderedLocusNames=HTH_1684 {ECO:0000313|EMBL:BAI70131.1};
OS Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6).
OC Bacteria; Pseudomonadati; Aquificota; Aquificia; Aquificales; Aquificaceae;
OC Hydrogenobacter.
OX NCBI_TaxID=608538 {ECO:0000313|EMBL:BAI70131.1, ECO:0000313|Proteomes:UP000002574};
RN [1] {ECO:0000313|EMBL:BAI70131.1, ECO:0000313|Proteomes:UP000002574}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 6534 / IAM 12695 / TK-6 [Tokyo]
RC {ECO:0000313|Proteomes:UP000002574};
RX PubMed=20348262; DOI=10.1128/JB.00158-10;
RA Arai H., Kanbe H., Ishii M., Igarashi Y.;
RT "Complete genome sequence of the thermophilic, obligately
RT chemolithoautotrophic hydrogen-oxidizing bacterium Hydrogenobacter
RT thermophilus TK-6.";
RL J. Bacteriol. 192:2651-2652(2010).
CC -!- FUNCTION: Required for formate dehydrogenase (FDH) activity. Acts as a
CC sulfur carrier protein that transfers sulfur from IscS to the
CC molybdenum cofactor prior to its insertion into FDH.
CC {ECO:0000256|HAMAP-Rule:MF_00187}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00187}.
CC -!- SIMILARITY: Belongs to the FdhD family. {ECO:0000256|HAMAP-
CC Rule:MF_00187}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|HAMAP-Rule:MF_00187}.
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DR EMBL; AP011112; BAI70131.1; -; Genomic_DNA.
DR RefSeq; WP_012964311.1; NC_013799.1.
DR AlphaFoldDB; D3DJX9; -.
DR STRING; 608538.HTH_1684; -.
DR KEGG; hte:Hydth_1669; -.
DR KEGG; hth:HTH_1684; -.
DR PATRIC; fig|608538.5.peg.1700; -.
DR eggNOG; COG1526; Bacteria.
DR OrthoDB; 9782042at2; -.
DR Proteomes; UP000002574; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0097163; F:sulfur carrier activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016783; F:sulfurtransferase activity; IEA:InterPro.
DR GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.10.20.10; -; 1.
DR Gene3D; 3.40.140.10; Cytidine Deaminase, domain 2; 1.
DR HAMAP; MF_00187; FdhD; 1.
DR InterPro; IPR016193; Cytidine_deaminase-like.
DR InterPro; IPR003786; FdhD.
DR NCBIfam; TIGR00129; fdhD_narQ; 1.
DR PANTHER; PTHR30592; FORMATE DEHYDROGENASE; 1.
DR PANTHER; PTHR30592:SF1; SULFUR CARRIER PROTEIN FDHD; 1.
DR Pfam; PF02634; FdhD-NarQ; 1.
DR PIRSF; PIRSF015626; FdhD; 1.
DR SUPFAM; SSF53927; Cytidine deaminase-like; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_00187};
KW Molybdenum cofactor biosynthesis {ECO:0000256|ARBA:ARBA00023150,
KW ECO:0000256|HAMAP-Rule:MF_00187};
KW Reference proteome {ECO:0000313|Proteomes:UP000002574}.
FT ACT_SITE 132
FT /note="Cysteine persulfide intermediate"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00187"
SQ SEQUENCE 311 AA; 35502 MW; 101CF84F4DDC76C4 CRC64;
MKKNPKIYRR DAYYEIPTLI LHRPNIPLWR KDLIVSEEPL EIRLVYPKGV DNWESLTLYT
TMRTPGEDED LVLGLLFSEG VIKSYKDVEY ISYCENVEEE KIGNVVNVFI KKYIDVEDFS
SLLRVSYMSS ACGLCGKLTI EYLKRIIPTC VKDDMFKLCD EYFYSLPDIL RKHQEKFLLT
GGTHACAAFD VEGNLIGVRE DVGRHNAMDK LIGYMLRIGK IPLKRTCIVV SGRASYELVQ
KALMAGVPIL ASIGAPSTLA VKLAKEFGMT LVGFLSRKRF VVYNDVGRLD LDKWLHETNL
LSMFKNSQSN D
//
