ID D7G089_ECTSI Unreviewed; 483 AA.
AC D7G089;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 28-JAN-2026, entry version 40.
DE SubName: Full=Similar to 3-Dehydroquinate Synthase {ECO:0000313|EMBL:CBJ32971.1};
DE EC=4.2.3.4 {ECO:0000313|EMBL:CBJ32971.1};
GN ORFNames=Esi_0398_0021 {ECO:0000313|EMBL:CBJ32971.1};
OS Ectocarpus siliculosus (Brown alga) (Conferva siliculosa).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; PX clade; Phaeophyceae;
OC Ectocarpales; Ectocarpaceae; Ectocarpus.
OX NCBI_TaxID=2880 {ECO:0000313|EMBL:CBJ32971.1, ECO:0000313|Proteomes:UP000002630};
RN [1] {ECO:0000313|EMBL:CBJ32971.1, ECO:0000313|Proteomes:UP000002630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ec32 / CCAP1310/4 {ECO:0000313|Proteomes:UP000002630};
RX PubMed=20520714; DOI=10.1038/nature09016;
RA Cock J.M., Sterck L., Rouze P., Scornet D., Allen A.E., Amoutzias G.,
RA Anthouard V., Artiguenave F., Aury J.M., Badger J.H., Beszteri B.,
RA Billiau K., Bonnet E., Bothwell J.H., Bowler C., Boyen C., Brownlee C.,
RA Carrano C.J., Charrier B., Cho G.Y., Coelho S.M., Collen J., Corre E.,
RA Da Silva C., Delage L., Delaroque N., Dittami S.M., Doulbeau S., Elias M.,
RA Farnham G., Gachon C.M., Gschloessl B., Heesch S., Jabbari K., Jubin C.,
RA Kawai H., Kimura K., Kloareg B., Kupper F.C., Lang D., Le Bail A.,
RA Leblanc C., Lerouge P., Lohr M., Lopez P.J., Martens C., Maumus F.,
RA Michel G., Miranda-Saavedra D., Morales J., Moreau H., Motomura T.,
RA Nagasato C., Napoli C.A., Nelson D.R., Nyvall-Collen P., Peters A.F.,
RA Pommier C., Potin P., Poulain J., Quesneville H., Read B., Rensing S.A.,
RA Ritter A., Rousvoal S., Samanta M., Samson G., Schroeder D.C., Segurens B.,
RA Strittmatter M., Tonon T., Tregear J.W., Valentin K., von Dassow P.,
RA Yamagishi T., Van de Peer Y., Wincker P.;
RT "The Ectocarpus genome and the independent evolution of multicellularity in
RT brown algae.";
RL Nature 465:617-621(2010).
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DR EMBL; FN649760; CBJ32971.1; -; Genomic_DNA.
DR AlphaFoldDB; D7G089; -.
DR STRING; 2880.D7G089; -.
DR eggNOG; ENOG502QSUR; Eukaryota.
DR InParanoid; D7G089; -.
DR OrthoDB; 3275at2759; -.
DR Proteomes; UP000002630; Unassembled WGS sequence.
DR GO; GO:0003856; F:3-dehydroquinate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0008652; P:amino acid biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR InterPro; IPR002812; DHQS.
DR InterPro; IPR030960; DHQS/DOIS_N.
DR InterPro; IPR056179; DHQS_C.
DR PANTHER; PTHR33563; -; 1.
DR PANTHER; PTHR33563:SF1; 3-DEHYDROQUINATE SYNTHASE; 1.
DR Pfam; PF01959; DHQS; 1.
DR Pfam; PF26558; DHQS_2nd; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Aromatic amino acid biosynthesis {ECO:0000256|ARBA:ARBA00023141};
KW Lyase {ECO:0000313|EMBL:CBJ32971.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002630};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..483
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003095651"
FT DOMAIN 96..235
FT /note="3-dehydroquinate synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01959"
FT DOMAIN 284..423
FT /note="3-dehydroquinate synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF26558"
FT REGION 418..450
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 483 AA; 50225 MW; C5A7B9BE674F6684 CRC64;
MRDRPRSHML SSSTPCVLMA LAGVNHGVLG FVSQSIAPTT SVLSTCRACL RTCGTAAAAA
GLSHPAAVRH AVKRRRFDSA LGCASAATGT SRPLELWLDA RGAKADGAVS ESALFQDQAD
TVLRDDNTTG KLRSTSKRSL VVKDDGKLMD EKGTVVGASL EVTDPKSQSR ALSLVGSVDW
IQVTCSDWTM IPAENLVSAA GGTPTRIAVE LSEPSQVQGA AFALQIGVDA LLLGPDPDLW
EAAVSAREQR GTDGPATGVL PAPADHGEGG AGGGLDVVAL STGRVTRTRE GGVGDRVCVD
LIQSLNAGEG MLVGSSAKML ALVHAETFET GFVPARPFRI NAGPVHSYAL LGDGSTKYLS
ELCAGDQVLV TNWKGESRKV AIGRLKVETR PMIMVEFQGE GGSTGQLFLQ QAETVRLISP
TQPETTAEKN SNESESEADS SGSGGGWVPL SVTDIEGGED LLLREISRGT HVGRAIDAVV
TET
//
