ID E0CXQ2_MOUSE Unreviewed; 571 AA.
AC E0CXQ2;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 28-JAN-2026, entry version 74.
DE SubName: Full=Proline rich 35 {ECO:0000313|Ensembl:ENSMUSP00000125106.2};
GN Name=Prr35 {ECO:0000313|Ensembl:ENSMUSP00000125106.2,
GN ECO:0000313|MGI:MGI:2442713};
GN Synonyms=A930017K11Rik {ECO:0000313|MGI:MGI:2442713};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000125106.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000125106.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000125106.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RG Mouse Genome Sequencing Consortium;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000125106.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000125106.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=21750661;
RA Church D.M., Schneider V.A., Graves T., Auger K., Cunningham F., Bouk N.,
RA Chen H.C., Agarwala R., McLaren W.M., Ritchie G.R., Albracht D.,
RA Kremitzki M., Rock S., Kotkiewicz H., Kremitzki C., Wollam A., Trani L.,
RA Fulton L., Fulton R., Matthews L., Whitehead S., Chow W., Torrance J.,
RA Dunn M., Harden G., Threadgold G., Wood J., Collins J., Heath P.,
RA Griffiths G., Pelan S., Grafham D., Eichler E.E., Weinstock G.,
RA Mardis E.R., Wilson R.K., Howe K., Flicek P., Hubbard T.;
RT "Modernizing reference genome assemblies.";
RL PLoS Biol. 9:e1001091-e1001091(2011).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000125106.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000125106.2};
RG Ensembl;
RL Submitted (AUG-2025) to UniProtKB.
RN [4] {ECO:0000313|Ensembl:ENSMUSP00000125106.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000125106.2};
RG Ensembl;
RL Submitted (SEP-2025) to UniProtKB.
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DR RefSeq; NP_001344948.1; NM_001358019.1.
DR RefSeq; XP_030105253.1; XM_030249393.2.
DR RefSeq; XP_030105254.1; XM_030249394.2.
DR AlphaFoldDB; E0CXQ2; -.
DR SMR; E0CXQ2; -.
DR FunCoup; E0CXQ2; 22.
DR STRING; 10090.ENSMUSP00000125106; -.
DR PaxDb; 10090-ENSMUSP00000125106; -.
DR ProteomicsDB; 311887; -.
DR Antibodypedia; 68294; 6 antibodies from 6 providers.
DR Ensembl; ENSMUST00000162431.2; ENSMUSP00000125106.2; ENSMUSG00000025727.9.
DR GeneID; 100034748; -.
DR KEGG; mmu:100034748; -.
DR UCSC; uc008bcv.1; mouse.
DR AGR; MGI:2442713; -.
DR CTD; 146325; -.
DR MGI; MGI:2442713; Prr35.
DR VEuPathDB; HostDB:ENSMUSG00000025727; -.
DR eggNOG; ENOG502QRT7; Eukaryota.
DR GeneTree; ENSGT00530000063870; -.
DR HOGENOM; CLU_022992_0_0_1; -.
DR InParanoid; E0CXQ2; -.
DR OMA; WKPGMGG; -.
DR OrthoDB; 9885698at2759; -.
DR Proteomes; UP000000589; Chromosome 17.
DR RNAct; E0CXQ2; protein.
DR Bgee; ENSMUSG00000025727; Expressed in placenta labyrinth and 33 other cell types or tissues.
DR InterPro; IPR039363; ZNF750.
DR InterPro; IPR039064; ZNF750_Znf.
DR PANTHER; PTHR14678:SF2; PROLINE-RICH PROTEIN 35; 1.
DR PANTHER; PTHR14678; PROLINE-RICH PROTEIN 35-RELATED; 1.
DR Pfam; PF15269; zf-C2H2_7; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|ProteomicsDB:E0CXQ2};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 18..68
FT /note="Zinc finger protein 750-like zinc finger"
FT /evidence="ECO:0000259|Pfam:PF15269"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 80..155
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 271..345
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 363..396
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 513..571
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..26
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 91..103
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 312..322
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 547..560
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 571 AA; 60301 MW; 6648A442C25D582C CRC64;
MSREAGSCRV GTGTRARSRK PKKPHYIPRP WGKPYNYKCF QCPFTCLEKS HLYNHMKYSL
CKDSLSLLLD SPDWACRRAP PSPRPRVPTP NCSTDFSDPS SKPTEPDLIV TDSFSQRRSG
RGPKPGPEES PGSLPPLARP IRKGPGTSGL LAESWKPGLS GGMLSGTLGT IASTPGSESS
VPCYPPPAQG EFPEAQSLHL SLLGVNYPLG PGLFSYLGPS LAAAAAHMPF LASASPLLPP
TAFPAPQTPE RPGLAPRLYY PLLLEHSLGQ SSGRAAPAKS SVPLKGPPGA LSAPGLLKVP
VPGPGGPWPH GTSRDPGHEG ELGRVTQSNP QKRLPTGNMP ELPKAPLNLA KFGCQSSLPT
GSSLLLWPED KEPGDPEASG PEFHLLQHPQ GQGLGSTVPV GEDLTQAFGD YARVEQCLGQ
LAPAGGLAPR PLREQLGKIR RELFTIHQAL ARAARPLDTP LDLSVKRVPT KGTEAPSESW
RLHDPGPVLA RGTSEPSSIL GPVLESFSSR TTKCEADSSV PPPVLPLQAP EDPVIPGSGW
GNRLGAGSSQ TPKDTPSLQI LPSADFCSQP P
//
