ID F0XIX8_GROCL Unreviewed; 327 AA.
AC F0XIX8;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 10-JUN-2026, entry version 44.
DE SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:EFX02343.1};
GN ORFNames=CMQ_2392 {ECO:0000313|EMBL:EFX02343.1};
OS Grosmannia clavigera (strain kw1407 / UAMH 11150) (Blue stain fungus)
OS (Graphiocladiella clavigera).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Leptographium.
OX NCBI_TaxID=655863 {ECO:0000313|EMBL:EFX02343.1, ECO:0000313|Proteomes:UP000007796};
RN [1] {ECO:0000313|EMBL:EFX02343.1, ECO:0000313|Proteomes:UP000007796}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=kw1407 / UAMH 11150 {ECO:0000313|Proteomes:UP000007796};
RX PubMed=21262841; DOI=10.1073/pnas.1011289108;
RA DiGuistini S., Wang Y., Liao N.Y., Taylor G., Tanguay P., Feau N.,
RA Henrissat B., Chan S.K., Hesse-Orce U., Alamouti S.M., Tsui C.K.M.,
RA Docking R.T., Levasseur A., Haridas S., Robertson G., Birol I., Holt R.A.,
RA Marra M.A., Hamelin R.C., Hirst M., Jones S.J.M., Bohlmann J., Breuil C.;
RT "Genome and transcriptome analyses of the mountain pine beetle-fungal
RT symbiont Grosmannia clavigera, a lodgepole pine pathogen.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:2504-2509(2011).
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DR EMBL; GL629782; EFX02343.1; -; Genomic_DNA.
DR RefSeq; XP_014171825.1; XM_014316350.1.
DR AlphaFoldDB; F0XIX8; -.
DR FunCoup; F0XIX8; 206.
DR STRING; 655863.F0XIX8; -.
DR GeneID; 25975376; -.
DR eggNOG; KOG2380; Eukaryota.
DR HOGENOM; CLU_031403_0_0_1; -.
DR InParanoid; F0XIX8; -.
DR OrthoDB; 5399569at2759; -.
DR Proteomes; UP000007796; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:TreeGrafter.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:EnsemblFungi.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:L-tyrosine biosynthetic process; IEA:EnsemblFungi.
DR FunFam; 1.10.3660.10:FF:000004; Prephenate dehydrogenase [NADP(+)]; 1.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 2.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR050812; Preph/Arog_dehydrog.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF27505; 6PGD_Tyr1_C; 1.
DR Pfam; PF20463; PDH_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 2.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000007796}.
FT DOMAIN 1..182
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 327 AA; 37262 MW; CF72FCE011993891 CRC64;
MKAFEEYLPD DVDIVSCHSL HGPNVDTRGQ PLVMIKHRAS DESFAKVETV LSCLGSKHVY
LTAALHDRIT ADTQAVTHVA FLSMGKAWHA MQQFPWEGAR YVGGIENVKI NLMLRIYAQK
WHVYAGLAIM NPEARKQIAQ YAASTTELYK LMLEGRSDDL RRRVYEAKDR VFGTFENPKW
AEKPLLNDGL LDRFGLGERP ESVLPNNHLS LLAMVDCWSK LGIVPYDHML CSTPLFRLRL
GVTENLFRDS EKLDAALRVA IEDNTFRSDD LEFTFAARGW AECVNLGHFD TWKERFDVTQ
QFFQPRFASA IQVGNEMMRA LLESKTG
//
