ID F1LZA7_RAT Unreviewed; 776 AA.
AC F1LZA7;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 08-OCT-2025, sequence version 5.
DT 10-JUN-2026, entry version 75.
DE SubName: Full=Junctional cadherin complex regulator {ECO:0000313|Ensembl:ENSRNOP00000010743.9};
GN Name=Jhy {ECO:0000313|Ensembl:ENSRNOP00000010743.9,
GN ECO:0000313|RGD:1309108};
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116 {ECO:0000313|Ensembl:ENSRNOP00000010743.9, ECO:0000313|Proteomes:UP000002494};
RN [1] {ECO:0000313|Ensembl:ENSRNOP00000010743.9}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000010743.9};
RA Doris P.A., Kalbfleisch T., Li K., Howe K., Wood J.;
RT "GRCr8: a new rat reference genome assembly contstructed from accurate long
RT reads and long range scaffolding.";
RL Submitted (JAN-2024) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSRNOP00000010743.9}
RP IDENTIFICATION.
RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000010743.9};
RG Ensembl;
RL Submitted (JAN-2026) to UniProtKB.
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DR RefSeq; NP_001416378.1; NM_001429449.1.
DR AlphaFoldDB; F1LZA7; -.
DR FunCoup; F1LZA7; 5.
DR STRING; 10116.ENSRNOP00000010743; -.
DR PaxDb; 10116-ENSRNOP00000010743; -.
DR Ensembl; ENSRNOT00000010743.9; ENSRNOP00000010743.9; ENSRNOG00000008138.9.
DR GeneID; 315578; -.
DR AGR; RGD:1309108; -.
DR CTD; 79864; -.
DR RGD; 1309108; Jhy.
DR VEuPathDB; HostDB:ENSRNOG00000008138; -.
DR eggNOG; ENOG502S6KC; Eukaryota.
DR GeneTree; ENSGT00390000002823; -.
DR HOGENOM; CLU_407472_0_0_1; -.
DR InParanoid; F1LZA7; -.
DR OMA; WKFHPSS; -.
DR Proteomes; UP000002494; Chromosome 8.
DR Bgee; ENSRNOG00000008138; Expressed in testis and 5 other cell types or tissues.
DR GO; GO:0005576; C:extracellular region; IEA:GOC.
DR GO; GO:0035082; P:axoneme assembly; ISO:RGD.
DR GO; GO:0007420; P:brain development; ISO:RGD.
DR GO; GO:0030154; P:cell differentiation; ISO:RGD.
DR GO; GO:0090660; P:cerebrospinal fluid circulation; ISO:RGD.
DR GO; GO:0044458; P:motile cilium assembly; ISO:RGD.
DR GO; GO:0090175; P:regulation of establishment of planar polarity; ISO:RGD.
DR InterPro; IPR027968; JHY.
DR PANTHER; PTHR14726; JHY PROTEIN HOMOLOG; 1.
DR PANTHER; PTHR14726:SF1; JHY PROTEIN HOMOLOG; 1.
DR Pfam; PF15261; JHY; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002494}.
FT REGION 1..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 321..438
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 496..533
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 597..651
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 719..745
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..24
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 53..74
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 75..87
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 110..132
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 220..230
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 341..355
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 356..367
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 380..397
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 413..432
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 512..523
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 524..533
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 629..648
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 776 AA; 88563 MW; 5B442BF2BC6A37C5 CRC64;
MPLWMNKYKP VPKRSSRSPV HHTNLRTPPS GRAFKEEDFN LISKDSLESD SESLPREAKF
WSDIKDQIQD KDMEPDSLEE DSSSETEEAA HGTNREGLGA QGAGANHSHH QVEDKYSDLR
YDPNWKNKKE EGQLLAVEAL PESADSSSDN LPGAPLYPSR EPSMRLSVGK GKEKRSPQSE
ASLLGSEFLS PKYECGTRQN EFFSELSDSD QEDQEEKSSD LSPYLKSSSS HNEVFLPGSR
GPRRRKSRQY FVEKNKLTLG LPAPKTDSYL QLHNKKRGET RLEQISYPIR DAGKMTVQDD
KGVENTFMDP EDKWHQRAKQ LKNYQEHLSQ CEDTKSGNVP RGQSSNAANV QQPSRRTAKA
RVQKQKKYQN GLKSLGTKEQ VVSQNNQNNS LQQPQTQRLP MDTSSKHEPA AQMTASNPNL
QDPRTLTHNP KVTSDPFFPP KETFDRVVYK NSVLGLNTNK RRGHRYKEEK RILYQQQPIY
IFSDGDLQDF NELSHRHESL SQRGPQSDYR MNTHRSRSTK TKKPSKEPEA ETKYKNIEML
WKLHSSSDME PVSASPDSRL AQIMEQHQQA LLQLAEVQPS EGSLSSTVFP PILSRVESES
QLDSERSHKH QMRMARSNSE GYLLQLEKGK RHRKRSQSRT KSSKLKGYQK RDVKLGGLGP
DFASIRDKMQ TLLQQKEYAK QVKEYNMKTL SVLSKPQTSK TDSKSTISRK KALDYAKTIP
KPKPPNLPYQ TMKKTNNSKH SEKEGSLPEI SLLEILQSRH EREKQAVAAF KVLHIV
//
