ID F4RA15_MELLP Unreviewed; 707 AA.
AC F4RA15;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 08-OCT-2025, entry version 58.
DE RecName: Full=DBF4-type domain-containing protein {ECO:0000259|PROSITE:PS51265};
GN ORFNames=MELLADRAFT_103324 {ECO:0000313|EMBL:EGG10646.1};
OS Melampsora larici-populina (strain 98AG31 / pathotype 3-4-7) (Poplar leaf
OS rust fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Pucciniomycetes; Pucciniales; Melampsoraceae; Melampsora.
OX NCBI_TaxID=747676 {ECO:0000313|Proteomes:UP000001072};
RN [1] {ECO:0000313|Proteomes:UP000001072}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=98AG31 / pathotype 3-4-7 {ECO:0000313|Proteomes:UP000001072};
RX PubMed=21536894; DOI=10.1073/pnas.1019315108;
RA Duplessis S., Cuomo C.A., Lin Y.-C., Aerts A., Tisserant E.,
RA Veneault-Fourrey C., Joly D.L., Hacquard S., Amselem J., Cantarel B.L.,
RA Chiu R., Coutinho P.M., Feau N., Field M., Frey P., Gelhaye E.,
RA Goldberg J., Grabherr M.G., Kodira C.D., Kohler A., Kuees U.,
RA Lindquist E.A., Lucas S.M., Mago R., Mauceli E., Morin E., Murat C.,
RA Pangilinan J.L., Park R., Pearson M., Quesneville H., Rouhier N.,
RA Sakthikumar S., Salamov A.A., Schmutz J., Selles B., Shapiro H.,
RA Tanguay P., Tuskan G.A., Henrissat B., Van de Peer Y., Rouze P.,
RA Ellis J.G., Dodds P.N., Schein J.E., Zhong S., Hamelin R.C.,
RA Grigoriev I.V., Szabo L.J., Martin F.;
RT "Obligate biotrophy features unraveled by the genomic analysis of rust
RT fungi.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:9166-9171(2011).
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DR EMBL; GL883094; EGG10646.1; -; Genomic_DNA.
DR RefSeq; XP_007406115.1; XM_007406053.1.
DR AlphaFoldDB; F4RA15; -.
DR FunCoup; F4RA15; 78.
DR STRING; 747676.F4RA15; -.
DR GeneID; 18921939; -.
DR KEGG; mlr:MELLADRAFT_103324; -.
DR VEuPathDB; FungiDB:MELLADRAFT_103324; -.
DR eggNOG; KOG4139; Eukaryota.
DR HOGENOM; CLU_017715_1_0_1; -.
DR InParanoid; F4RA15; -.
DR OrthoDB; 21380at2759; -.
DR Proteomes; UP000001072; Unassembled WGS sequence.
DR GO; GO:0031431; C:Dbf4-dependent protein kinase complex; IEA:TreeGrafter.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0043539; F:protein serine/threonine kinase activator activity; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0010571; P:positive regulation of nuclear cell cycle DNA replication; IEA:TreeGrafter.
DR GO; GO:1901987; P:regulation of cell cycle phase transition; IEA:TreeGrafter.
DR CDD; cd00027; BRCT; 1.
DR FunFam; 6.10.250.3410:FF:000001; Protein DBF4 homolog A; 1.
DR Gene3D; 6.10.250.3410; DBF zinc finger; 1.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR055116; DBF4_BRCT.
DR InterPro; IPR013939; Regulatory_Dfp1/Him1.
DR InterPro; IPR051590; Replication_Regulatory_Kinase.
DR InterPro; IPR006572; Znf_DBF.
DR InterPro; IPR038545; Znf_DBF_sf.
DR PANTHER; PTHR15375; ACTIVATOR OF S-PHASE KINASE-RELATED; 1.
DR PANTHER; PTHR15375:SF26; PROTEIN CHIFFON; 1.
DR Pfam; PF22437; DBF4_BRCT; 1.
DR Pfam; PF08630; Dfp1_Him1_M; 1.
DR Pfam; PF07535; zf-DBF; 1.
DR SMART; SM00586; ZnF_DBF; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR PROSITE; PS51265; ZF_DBF4; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001072};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00600}.
FT DOMAIN 593..642
FT /note="DBF4-type"
FT /evidence="ECO:0000259|PROSITE:PS51265"
FT REGION 1..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 172..223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 325..345
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 383..417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 677..707
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..31
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..57
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 331..341
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 396..405
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 707 AA; 80842 MW; 7FBE3B68CBF0E07C CRC64;
MKLSHQNQNQ QNPKSFSIHS PDSQPKSQSQ SFLPPPPPTT TTTTTTTLTT KPITPITNHT
LPNLINEKDS RSHFNRDKQR VKDELRRETL QWQEKYRVAI KSFVFYLDRL DSKTESELSN
ELESWGARVD QFFSKDVTHV ITNIPVPVNL PILSPSVTNS IKRNTAYQLP VPSPSPSTLH
VHPSHPLHFN NKENGPLTRR SSKRILEPNL VSPDPKDGIL TDPPQIDPFM RKALEMKIKI
WRTEKLRNVL ERLEDRRSPM KPLPLMKPSL PSLLAKEAQQ GHTHERDPIS IRSDYHYFSK
QSNFILVEDS NQEFKPIIIK EFTKSKVKDP SASTSTSAST SNQTWPVLFG GTEGKSAFSK
YNSKHSLNHV HLRIKQMFEE RFKESNTNSN LEDNPNRTPN PNQNRDYLSI PTSQPTQSLR
RTMSMNILQR KQTVQLNPTH SKANHQEGLY PDLVNITALE HQRGPGKVFL GASGNSVTIT
STNTPSTRSS LAYQSNFLVD KRLNELVKRP TFKILDNLKK ENQLVGGGEK NLKRCQSLDQ
ALLEQKKQTD GIGCTNKNQE SRRRRGGRKG LGVRDKLGEG FELLDLSNLV GEEEAKAGYC
ENCRTKYGDF KRHVITRKHR KFATNEDNWW ELDKLLERTC RRLRVDCGDL PPSLRELIEL
RDQRMGLEDE DEEIKIMNND NDDNSNDDNN NINDDGDNDG GNLWVGF
//
