ID F8KR23_HELBC Unreviewed; 429 AA.
AC F8KR23;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 28-JAN-2026, entry version 61.
DE SubName: Full=Apolipoprotein N-acyltransferase {ECO:0000313|EMBL:CCB79194.1};
GN OrderedLocusNames=HBZC1_02080 {ECO:0000313|EMBL:CCB79194.1};
OS Helicobacter bizzozeronii (strain CIII-1).
OC Bacteria; Pseudomonadati; Campylobacterota; Epsilonproteobacteria;
OC Campylobacterales; Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1002804 {ECO:0000313|EMBL:CCB79194.1, ECO:0000313|Proteomes:UP000008387};
RN [1] {ECO:0000313|EMBL:CCB79194.1, ECO:0000313|Proteomes:UP000008387}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CIII-1 {ECO:0000313|EMBL:CCB79194.1,
RC ECO:0000313|Proteomes:UP000008387};
RX PubMed=21705603; DOI=10.1128/JB.05439-11;
RA Schott T., Rossi M., Hanninen M.L.;
RT "Genome sequence of Helicobacter bizzozeronii strain CIII-1, an isolate
RT from human gastric mucosa.";
RL J. Bacteriol. 193:4565-4566(2011).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC -!- SIMILARITY: Belongs to the CN hydrolase family. Apolipoprotein N-
CC acyltransferase subfamily. {ECO:0000256|ARBA:ARBA00010065}.
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DR EMBL; FR871757; CCB79194.1; -; Genomic_DNA.
DR AlphaFoldDB; F8KR23; -.
DR STRING; 1002804.HBZC1_02080; -.
DR KEGG; hbi:HBZC1_02080; -.
DR eggNOG; COG0815; Bacteria.
DR HOGENOM; CLU_050649_0_0_7; -.
DR Proteomes; UP000008387; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016410; F:N-acyltransferase activity; IEA:InterPro.
DR GO; GO:0042158; P:lipoprotein biosynthetic process; IEA:InterPro.
DR Gene3D; 3.60.110.10; Carbon-nitrogen hydrolase; 1.
DR InterPro; IPR004563; Apolipo_AcylTrfase.
DR InterPro; IPR003010; C-N_Hydrolase.
DR InterPro; IPR036526; C-N_Hydrolase_sf.
DR InterPro; IPR059110; Lnt_campylobact.
DR InterPro; IPR059109; Lnt_membrane_dom.
DR NCBIfam; TIGR00546; lnt; 1.
DR NCBIfam; NF008934; PRK12291.1; 1.
DR PANTHER; PTHR38686; APOLIPOPROTEIN N-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR38686:SF1; APOLIPOPROTEIN N-ACYLTRANSFERASE; 1.
DR Pfam; PF26365; ApoNAT_membrane; 1.
DR Pfam; PF00795; CN_hydrolase; 1.
DR SUPFAM; SSF56317; Carbon-nitrogen hydrolase; 1.
DR PROSITE; PS50263; CN_HYDROLASE; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000313|EMBL:CCB79194.1};
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Lipoprotein {ECO:0000313|EMBL:CCB79194.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008387};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:CCB79194.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 40..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 149..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 210..429
FT /note="CN hydrolase"
FT /evidence="ECO:0000259|PROSITE:PS50263"
SQ SEQUENCE 429 AA; 49307 MW; 4E96B548140AB90C CRC64;
MVLCLCDRYW RGYGFVCVCV LLFLLPVYGS LLLAHHPMPL VIFGSFSAPL SVWAYLSVPA
KRRFFFGFWV GLGLFYWCAL SFRYNDNVFL LPLIMVLIAL CYAVVFYGLL YFNSLLYRIA
TLWLSSYIHP FGFDWFVPDA FFAYSGFKVD RLSFLGVIVA IALFMQRYKN FMFFKPLYAP
SKIFAVVLLV LSINWKQSAS ALDPNALKVV QTNTNQKTKW QPEFLDATIA FNLTTIQQAI
QEKKQVVILP ETAFPIALNK SNLIPTLLSL SQQITIIAGA LYEENDTIYN STYVFDHGDY
HYAHKVILAP FGERMPLPSF LADYLDRFFF GADVFKLGNA PHFSDMKTQH LDFRPLVCYE
GTSKPAYENS PPNLVVISNN AWFVPSIEPF LQRMLLKYYA RRFDKTIIHS VNFSPSYILT
PALLGDRLY
//
