ID   G0MMG6_CAEBE            Unreviewed;       402 AA.
AC   G0MMG6;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   02-APR-2025, entry version 52.
DE   RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE            EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
GN   ORFNames=CAEBREN_22382 {ECO:0000313|EMBL:EGT37351.1};
OS   Caenorhabditis brenneri (Nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN   [1] {ECO:0000313|Proteomes:UP000008068}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG   Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA   Wilson R.K.;
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC         [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC         cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC         EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
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DR   EMBL; GL379802; EGT37351.1; -; Genomic_DNA.
DR   AlphaFoldDB; G0MMG6; -.
DR   STRING; 135651.G0MMG6; -.
DR   EnsemblMetazoa; CBN22382.1; CBN22382.1; WBGene00161107.
DR   eggNOG; KOG1815; Eukaryota.
DR   HOGENOM; CLU_009823_4_3_1; -.
DR   InParanoid; G0MMG6; -.
DR   OrthoDB; 1431934at2759; -.
DR   Proteomes; UP000008068; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR   Gene3D; 1.20.120.1750; -; 1.
DR   InterPro; IPR031127; E3_UB_ligase_RBR.
DR   InterPro; IPR002867; IBR_dom.
DR   InterPro; IPR044066; TRIAD_supradom.
DR   PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR   Pfam; PF01485; IBR; 1.
DR   Pfam; PF22191; IBR_1; 1.
DR   SMART; SM00647; IBR; 2.
DR   SUPFAM; SSF57850; RING/U-box; 2.
DR   PROSITE; PS51873; TRIAD; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008068};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   TRANSMEM        336..358
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        382..401
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..172
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51873"
SQ   SEQUENCE   402 AA;  46322 MW;  E72C83E2F7141A30 CRC64;
     MEDGNCLIKC MDPKCKLLIG KSFVNEFLND SAFYEKLIVN TFVKATHTIT KCPDATCKLF
     AKTSSAEPQT VTCTCDRIFC SSCSQDPHFP ATCRQQQLWI KKCDLLAPKI DDDSQQWLLE
     HTKECPRCLM AVEKQGGCTL MTCSNKKCRL KFCWSCRSDI ATHGIYYCNS SQLKAEKARL
     DARADLANFI THYNRFEYYQ TFVKNITPII NDALESSEPL LQKAAYSYFN ARKMLTNSVV
     FGFFLCSGEY SDKLKKLQHE LELSTDRLES SLIYALPTQR FRKCRSKLVQ NYRDMEKCQK
     DILQFCANAQ KFEDLDGQSN REAWKRAHDA RVTYDWVSLF LSYFVFAFVI PLALHVLLPD
     FSVVYGKTLG IELRNCSLQT NLRLIFLSLV TFFVASFFDL ID
//