ID   G0S4M1_CHATD            Unreviewed;       528 AA.
AC   G0S4M1;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   28-JAN-2026, entry version 45.
DE   RecName: Full=DAGKc domain-containing protein {ECO:0000259|PROSITE:PS50146};
GN   ORFNames=CTHT_0031500 {ECO:0000313|EMBL:EGS21296.1};
OS   Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)
OS   (Thermochaetoides thermophila).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Chaetomiaceae; Thermochaetoides.
OX   NCBI_TaxID=759272 {ECO:0000313|Proteomes:UP000008066};
RN   [1] {ECO:0000313|EMBL:EGS21296.1, ECO:0000313|Proteomes:UP000008066}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 1495 / CBS 144.50 / IMI 039719
RC   {ECO:0000313|Proteomes:UP000008066};
RX   PubMed=21784248; DOI=10.1016/j.cell.2011.06.039;
RA   Amlacher S., Sarges P., Flemming D., van Noort V., Kunze R., Devos D.P.,
RA   Arumugam M., Bork P., Hurt E.;
RT   "Insight into structure and assembly of the nuclear pore complex by
RT   utilizing the genome of a eukaryotic thermophile.";
RL   Cell 146:277-289(2011).
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DR   EMBL; GL988041; EGS21296.1; -; Genomic_DNA.
DR   RefSeq; XP_006693592.1; XM_006693529.1.
DR   AlphaFoldDB; G0S4M1; -.
DR   STRING; 759272.G0S4M1; -.
DR   GeneID; 18257188; -.
DR   KEGG; cthr:CTHT_0031500; -.
DR   eggNOG; KOG1116; Eukaryota.
DR   HOGENOM; CLU_013399_0_1_1; -.
DR   OMA; TIWTLYR; -.
DR   OrthoDB; 3853857at2759; -.
DR   Proteomes; UP000008066; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR   GO; GO:0016020; C:membrane; IEA:TreeGrafter.
DR   GO; GO:0001727; F:lipid kinase activity; IEA:UniProtKB-ARBA.
DR   GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:UniProtKB-ARBA.
DR   GO; GO:0046512; P:sphingosine biosynthetic process; IEA:TreeGrafter.
DR   Gene3D; 2.60.200.40; -; 1.
DR   Gene3D; 3.40.50.10330; Probable inorganic polyphosphate/atp-NAD kinase, domain 1; 1.
DR   InterPro; IPR017438; ATP-NAD_kinase_N.
DR   InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR   InterPro; IPR055916; DUF7493.
DR   InterPro; IPR050187; Lipid_Phosphate_FormReg.
DR   InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR   PANTHER; PTHR12358:SF31; ACYLGLYCEROL KINASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR12358; SPHINGOSINE KINASE; 1.
DR   Pfam; PF00781; DAGK_cat; 1.
DR   Pfam; PF24321; DUF7493; 1.
DR   SMART; SM00046; DAGKc; 1.
DR   SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
DR   PROSITE; PS50146; DAGK; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008066}.
FT   DOMAIN          141..280
FT                   /note="DAGKc"
FT                   /evidence="ECO:0000259|PROSITE:PS50146"
FT   REGION          350..374
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   528 AA;  57400 MW;  E285CA125E363253 CRC64;
     MALSAPSGQI DRSQLRDAAN GANGLNAANS AKHLSSDTDR VLVLSPGVTL TLGSDALLLS
     SANDTPNRIP YYNILWAEIV DDCRWLVIDY AGQTRAHHVE ARRAKFAIPD QTLEQSPAGI
     VDQVASWLEC LLDHAYAGGA ARRKRAWVLV NPHAGPGGAD KIWEKQVRPI FEAARMTLTV
     VRTSYSGQAV ELAQELNIDD YDVAVPCSGD GLPHEVFNGL AKRPDARRAL SKIAVCHIPC
     GSGNAMSCNL YGTHRPSLAA LAIVKGVPTP LDLVSITQGD RRIISFLSQA FGLIAEVDLG
     TEHLRWMGAA RFTFGFLKLA FQKKTYPCDI AVKVEIDDKQ AVKKHYRERI TSAASDRPND
     KQPSDPNGDG DALGLPPLKY GTVKDELPEG WELIRCEKLG SLYCGNMAYM APDANFFSAA
     LANDGLIDLI TTDGDISPFK AIGLQLSIES GHFFDNPLVT YRKISAFRII PRTKTAGYIS
     IDGEAIPWEP FQAEVHQGLG LTLSKKGIFE APGPRDWDSV TITERLLA
//