ID G1Q170_MYOLU Unreviewed; 832 AA.
AC G1Q170;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 28-JAN-2026, entry version 49.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMLUP00000017453.1};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000017453.1, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000017453.1, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000017453.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (AUG-2025) to UniProtKB.
RN [3] {ECO:0000313|Ensembl:ENSMLUP00000017453.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2025) to UniProtKB.
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DR EMBL; AAPE02039770; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1Q170; -.
DR STRING; 59463.ENSMLUP00000017453; -.
DR Ensembl; ENSMLUT00000025392.1; ENSMLUP00000017453.1; ENSMLUG00000030553.1.
DR eggNOG; KOG2231; Eukaryota.
DR HOGENOM; CLU_015828_0_0_1; -.
DR InParanoid; G1Q170; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR GO; GO:0043022; F:ribosome binding; IEA:TreeGrafter.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:TreeGrafter.
DR GO; GO:0072344; P:rescue of stalled ribosome; IEA:InterPro.
DR InterPro; IPR057634; PAH_ZNF598/HEL2.
DR InterPro; IPR044288; ZNF598/HEL2.
DR InterPro; IPR059042; Znf_C2H2_ZNF598.
DR PANTHER; PTHR22938:SF0; E3 UBIQUITIN-PROTEIN LIGASE ZNF598; 1.
DR PANTHER; PTHR22938; ZINC FINGER PROTEIN 598; 1.
DR Pfam; PF23202; PAH_ZNF598; 1.
DR Pfam; PF23208; zf_C2H2_ZNF598; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001074}.
FT DOMAIN 684..755
FT /note="ZNF598/HEL2 PAH"
FT /evidence="ECO:0000259|Pfam:PF23202"
FT DOMAIN 789..822
FT /note="ZNF598 C2H2 zinc finger"
FT /evidence="ECO:0000259|Pfam:PF23208"
FT REGION 264..379
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 481..505
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 753..789
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 264..279
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 282..291
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 306..321
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 774..789
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 832 AA; 89591 MW; 04AA768CF6094246 CRC64;
DLEAKALGCW HLCCATYHCS TRYECAGTVT LCRESCASGT SGTPWPQSHP PAALGAYSIY
FADGKFALYK QPPQHKCPRC PALPPSGLFD LEQTMRQQHE FFAKLCLKPL RIFRNERAWS
SHQALVQHRL LGPGDTQHRA PQPCMVCRER CLHKDERLST NKNVFYLCAS ATSDGGAAQG
CYSDSPYLHK HFPETHVLRG GRCSTSGRAP CLLHLWAPTS SHRTACIAPR TIRSTGKLAT
CGTGEGLLSG QDLEEVNKCN LTHQAGQVSG QGARQSRGSW RQRREGDREG AAIRASMALQ
QQQETCRSED RRGNALKKEE AGVWGPQGPR GGLRPVRGSG GRPGPKEAWA NGPESQEAFP
APSPAEDHTS EHPPAPTLKL KGTGFPVSTL PLPLLLQGAA LGPVGLVLLS PVLARGPAPA
GKATHLPDIL HLQAQHSPPP SPPLCPEEQW QLQGGAAHPS GPGCWGSQPP GRLRWGEGQL
EGRVTPHGGR GSEEEVEEEE KEGPTWHGRC LLPVALASTQ TFTKVSKNTK VGSEKLGAAS
PRQCPLRMMP PGAEQPPPPP GLHGLSPGAS SCHGQWTSRG LGLKSFPKEP PELPWPQGPP
IPHVPALRGP LPFRIPPPPG FSTAVLLRGT LSPLLDVVPS VSKSSLSFPR LPSPLPACVP
STTTRKAPRL TPVPRTYLGP ERGKNLRLTR SIKGFLQTGL QGVHDSLGEF RWGVISTAQY
YKSCSNLLWK KFQKIVNVAV LQPNRAQRQE LLSAHPGAEA KLGCPTEAKE NKKSSWQTSP
GQASTQQTGM DCCVRPTYQQ VPPNGEVSSH QALHTVQDGD FPSLPAVARA LT
//
