ID G3P3X7_GASAC Unreviewed; 497 AA.
AC G3P3X7;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 10-JUN-2026, entry version 67.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGACP00000012300.1};
OS Gasterosteus aculeatus aculeatus (three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=481459 {ECO:0000313|Ensembl:ENSGACP00000012300.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000012300.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lake Benthic {ECO:0000313|Ensembl:ENSGACP00000012300.1,
RC ECO:0000313|Proteomes:UP000007635};
RX PubMed=33598708;
RA Nath S., Shaw D.E., White M.A.;
RT "Improved contiguity of the threespine stickleback genome using long-read
RT sequencing.";
RL G3 (Bethesda) 11:0-0(2021).
RN [2] {ECO:0000313|Ensembl:ENSGACP00000012300.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JAN-2026) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome {ECO:0000256|ARBA:ARBA00004300}.
CC -!- SIMILARITY: Belongs to the translokin family.
CC {ECO:0000256|ARBA:ARBA00008179}.
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DR RefSeq; XP_040054899.1; XM_040198965.1.
DR AlphaFoldDB; G3P3X7; -.
DR STRING; 69293.ENSGACP00000012300; -.
DR Ensembl; ENSGACT00000012324.2; ENSGACP00000012300.1; ENSGACG00000009314.2.
DR eggNOG; ENOG502QTZR; Eukaryota.
DR GeneTree; ENSGT00530000063695; -.
DR InParanoid; G3P3X7; -.
DR OMA; TQNNAEM; -.
DR Proteomes; UP000007635; Chromosome I.
DR Bgee; ENSGACG00000009314; Expressed in embryo and 4 other cell types or tissues.
DR GO; GO:0005813; C:centrosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0043015; F:gamma-tubulin binding; IEA:InterPro.
DR GO; GO:0042802; F:identical protein binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR Gene3D; 1.20.58.90; -; 1.
DR InterPro; IPR051756; Centrosomal_MT-associated.
DR InterPro; IPR025913; Cep57_CLD.
DR InterPro; IPR024957; Cep57_MT-bd_dom.
DR PANTHER; PTHR19336:SF11; CENTROSOMAL PROTEIN OF 57 KDA; 1.
DR PANTHER; PTHR19336; UNCHARACTERIZED DUF1167; 1.
DR Pfam; PF14073; Cep57_CLD; 1.
DR Pfam; PF06657; Cep57_MT_bd; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635}.
FT DOMAIN 77..264
FT /note="Cep57 centrosome localisation"
FT /evidence="ECO:0000259|Pfam:PF14073"
FT DOMAIN 361..433
FT /note="Cep57 centrosome microtubule-binding"
FT /evidence="ECO:0000259|Pfam:PF06657"
FT REGION 1..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 268..295
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 346..371
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 445..478
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 74..101
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 148..182
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 208..249
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 376..426
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 8..19
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..60
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 61..72
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 348..358
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 360..371
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 445..456
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 497 AA; 56165 MW; B5F0F8DED5C29934 CRC64;
METLSKTADA DATREREPPA PRGVVSDSFS LPSYKDYPPH RPFINTLLHH TPKTRSHQPR
RSSSPGNAFP ETSSAEILSA LRNLQEKIMR LELEKGHAER GLHAVGQNVP YAPLQREEVA
QRLSGDHGEP EREISGESNN NQVLITHLAA AESRCLKLER QLDHMRRMLR SAKAERSSLL
RQQVSMETAR SAEKQPDTVC EQAQLETLER LEQEYLRLTH TQNNAEMKMR QLEIKLLEEE
HQRKLVQDKA NQLQTGLETN RILLQSVSPC LSSRPSKEKK SYSKKSSPQH SSCTQPHYRL
SLRDVPFVAG TSVGCSHSVR ANVQSVLSLL KRHQPHLCNR RVLSSDANGH ETGCRRPSDA
SSSSASASGG ELSELLQALE EELRLMSLER DELTGQVEAS VTDQERKELQ REQERLLQKM
ERKGEQINKL HKHRTHIKKL RKEANSRRSC GSERRVASTT SARGRCPAPV KVGPGERSKG
NLRLLRDMRA LQTSLRT
//
