ID   G5IIP1_9FIRM            Unreviewed;       313 AA.
AC   G5IIP1;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   28-JAN-2026, entry version 28.
DE   RecName: Full=Tox-PL-2 domain-containing protein {ECO:0000259|Pfam:PF15643};
GN   ORFNames=HMPREF9473_03368 {ECO:0000313|EMBL:EHI58675.1};
OS   Hungatella hathewayi WAL-18680.
OC   Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
OC   Lachnospiraceae; Hungatella.
OX   NCBI_TaxID=742737 {ECO:0000313|EMBL:EHI58675.1, ECO:0000313|Proteomes:UP000005384};
RN   [1] {ECO:0000313|EMBL:EHI58675.1, ECO:0000313|Proteomes:UP000005384}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WAL-18680 {ECO:0000313|EMBL:EHI58675.1,
RC   ECO:0000313|Proteomes:UP000005384};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Finegold S.M., Summanen P.H.,
RA   Molitoris D.R., Song M., Daigneault M., Allen-Vercoe E., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA   Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA   Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A.,
RA   Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA   Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Clostridium hathewayi WAL-18680.";
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EHI58675.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ADLN01000092; EHI58675.1; -; Genomic_DNA.
DR   RefSeq; WP_006781348.1; NZ_CP040506.1.
DR   AlphaFoldDB; G5IIP1; -.
DR   PATRIC; fig|742737.3.peg.3347; -.
DR   HOGENOM; CLU_887887_0_0_9; -.
DR   Proteomes; UP000005384; Unassembled WGS sequence.
DR   InterPro; IPR028910; Tox-PL-2_dom.
DR   Pfam; PF15643; Tox-PL-2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005384};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..31
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           32..313
FT                   /note="Tox-PL-2 domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003478723"
FT   TRANSMEM        106..130
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          219..293
FT                   /note="Tox-PL-2"
FT                   /evidence="ECO:0000259|Pfam:PF15643"
FT   REGION          178..198
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   313 AA;  34020 MW;  665E4132F0B4D7A1 CRC64;
     MSKKRKGLLK RTVAFLLTAV MCINMTVYSM AAGEQAAGTN AVITPQGTLE ITSDSIIIDG
     HVYSKAQFTQ ALEQIKRLPS EQVPEQPAGR SAVVALEFVG LGLGGVFAQI AFTLLMAGLI
     VSVLGIIYEL KAGTLPGLNR SIQIEIKDSQ SIYIDNVRVG ANWVTMATAE YLSEHYEEIE
     EAEGESDSGN NNMGDPNKNP DPTIMAGIIA KISDNLKDKV GTCDEFAKAL VEKLNQAGIK
     FEIIRIDSRV GIYSDKYGSS IGDKFHYGIR IGNMVYDNLT LAGMKCEDWL ADLGANGEFA
     DITWRIVKEI LNN
//