ID G8BGL5_LODP3 Unreviewed; 573 AA.
AC G8BGL5; A0AAJ8W4S5;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 04-NOV-2026, entry version 48.
DE RecName: Full=SUI1 domain-containing protein {ECO:0000259|PROSITE:PS50296};
GN OrderedLocusNames=CPAR2_502370 {ECO:0000313|CGD:CAL0000145917,
GN ECO:0000313|EMBL:CCE44012.1};
OS Lodderomyces parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Candida
OS parapsilosis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Pichiomycetes;
OC Debaryomycetaceae; Lodderomyces.
OX NCBI_TaxID=578454 {ECO:0000313|EMBL:CCE44012.1, ECO:0000313|Proteomes:UP000005221};
RN [1] {ECO:0000313|Proteomes:UP000005221}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 317 / ATCC MYA-4646 {ECO:0000313|Proteomes:UP000005221};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
RN [2] {ECO:0000313|Proteomes:UP000005221}
RP GENOME REANNOTATION.
RC STRAIN=CDC 317 / ATCC MYA-4646 {ECO:0000313|Proteomes:UP000005221};
RX PubMed=22192698; DOI=10.1186/1471-2164-12-628;
RA Guida A., Lindstaedt C., Maguire S.L., Ding C., Higgins D.G., Corton N.J.,
RA Berriman M., Butler G.;
RT "Using RNA-seq to determine the transcriptional landscape and the hypoxic
RT response of the pathogenic yeast Candida parapsilosis.";
RL BMC Genomics 12:628-628(2011).
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DR EMBL; HE605207; CCE44012.1; -; Genomic_DNA.
DR AlphaFoldDB; G8BGL5; -.
DR STRING; 578454.G8BGL5; -.
DR CGD; CAL0000145917; CPAR2_502370.
DR VEuPathDB; FungiDB:CPAR2_502370; -.
DR eggNOG; KOG2522; Eukaryota.
DR Proteomes; UP000005221; Chromosome 5.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:InterPro.
DR GO; GO:0001731; P:formation of translation preinitiation complex; IEA:InterPro.
DR CDD; cd11608; eIF2D_C; 1.
DR CDD; cd11610; eIF2D_N; 1.
DR CDD; cd21156; PUA_eIF2d-like; 1.
DR Gene3D; 3.10.400.20; -; 1.
DR Gene3D; 3.30.780.10; SUI1-like domain; 1.
DR InterPro; IPR039757; EIF2D.
DR InterPro; IPR048247; eIF2D_N.
DR InterPro; IPR039759; eIF2D_SUI1.
DR InterPro; IPR041366; Pre-PUA.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR048248; PUA_eIF2d-like.
DR InterPro; IPR001950; SUI1.
DR InterPro; IPR036877; SUI1_dom_sf.
DR InterPro; IPR058886; SWIB_eIF2D.
DR InterPro; IPR036885; SWIB_MDM2_dom_sf.
DR InterPro; IPR057429; WH_eIF2D.
DR PANTHER; PTHR12217; EUKARYOTIC TRANSLATION INITIATION FACTOR 2D; 1.
DR PANTHER; PTHR12217:SF4; EUKARYOTIC TRANSLATION INITIATION FACTOR 2D; 1.
DR Pfam; PF17832; Pre-PUA; 1.
DR Pfam; PF26292; PUA_elF2D; 1.
DR Pfam; PF01253; SUI1; 1.
DR Pfam; PF26291; SWIB_eIF2D; 1.
DR Pfam; PF25304; WHD_eIF2D; 1.
DR SUPFAM; SSF55159; eIF1-like; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR SUPFAM; SSF47592; SWIB/MDM2 domain; 1.
DR PROSITE; PS50890; PUA; 1.
DR PROSITE; PS50296; SUI1; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000005221}.
FT DOMAIN 487..554
FT /note="SUI1"
FT /evidence="ECO:0000259|PROSITE:PS50296"
FT REGION 204..245
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 210..222
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 236..245
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 573 AA; 64158 MW; 784C00C7172C1E03 CRC64;
MFKKPPQVKP AANIKSSDRR KLLSTVCKTY NLPIDEIAKE GLDNLVPPIS KKATFTSPVD
KKLTGTIYFD SNEIPTWFQT RDSQLYPSLF TCWKCPYVLP LVKTHEPVIG VLGKGADLML
PGTIPPFDKR AVKNAVVGIV SKEKPNVIMA VGVCRLNLTQ FDYVVGRSGM AVEIIHHFDD
ELIKLNKEID VVIPEEVDAE FPKAAKEEVV ETGEDETTEI NEEPVSKPPE ADSIAGTDTT
GNENNTEIDD VAEELAQLTA EEVDNFFVRS LLQTIKLETV ELPINASTFM SSYIYKNLPI
LDSSYANIKK TSWKKTSKYL KAMAKSSYLE VKGKDEDLSI IKLMSRTNPT IENFVPHKIN
KVKKPTSSNS DGGSSSSSMM KITTLYKPTS KSRMFFNKLD ARFDHLYTLP ELRTMFNDYI
KLANLVNPTN PKQIIVDEII SNPTNKPNGS QVARDQIFTT FLTNFTPHYS ITSQQHSHLG
KGTPPKIHIV TEMKIGRKVI TRVGNYDKFF IKQGAFAEEL RKLCSGSTTI VDDEQVQVQG
PHGNTIINLL KEKGVPLGCI EFEDKVKKKK KRS
//
