ID H0EPI3_GLAL7 Unreviewed; 413 AA.
AC H0EPI3;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 10-JUN-2026, entry version 42.
DE SubName: Full=Putative prephenate dehydrogenase {ECO:0000313|EMBL:EHK99551.1};
GN ORFNames=M7I_4562 {ECO:0000313|EMBL:EHK99551.1};
OS Glarea lozoyensis (strain ATCC 74030 / MF5533).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Helotiaceae; Glarea.
OX NCBI_TaxID=1104152 {ECO:0000313|EMBL:EHK99551.1, ECO:0000313|Proteomes:UP000005446};
RN [1] {ECO:0000313|EMBL:EHK99551.1, ECO:0000313|Proteomes:UP000005446}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 74030 / MF5533 {ECO:0000313|Proteomes:UP000005446};
RX PubMed=22302591; DOI=10.1128/EC.05302-11;
RA Youssar L., Gruening B.A., Erxleben A., Guenther S., Huettel W.;
RT "Genome sequence of the fungus Glarea lozoyensis: the first genome sequence
RT of a species from the Helotiaceae family.";
RL Eukaryot. Cell 11:250-250(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHK99551.1}.
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DR EMBL; AGUE01000112; EHK99551.1; -; Genomic_DNA.
DR AlphaFoldDB; H0EPI3; -.
DR FunCoup; H0EPI3; 154.
DR HOGENOM; CLU_031403_1_0_1; -.
DR InParanoid; H0EPI3; -.
DR OrthoDB; 5399569at2759; -.
DR Proteomes; UP000005446; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:TreeGrafter.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:L-tyrosine biosynthetic process; IEA:InterPro.
DR FunFam; 1.10.3660.10:FF:000002; Prephenate dehydrogenase [NADP(+)]; 1.
DR FunFam; 1.10.3660.10:FF:000004; Prephenate dehydrogenase [NADP(+)]; 1.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 2.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR050812; Preph/Arog_dehydrog.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF27505; 6PGD_Tyr1_C; 1.
DR Pfam; PF20463; PDH_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 2.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000005446}.
FT DOMAIN 1..240
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 413 AA; 46522 MW; 68C9D3233155DAB4 CRC64;
MASTQVITGP DDMSNFSIGI IGLGDMGKMY ARRLSDNGWR SATKQNAIVG GQTSCKAPEI
AAFEKYLPAD VDIISCHSLH GPAVDPHNQP LVITLTLVWV FVFEKVKKVL SCLGSTHVYL
SAAQHDRITA DTQAVTHAAF LSMGKAWHAN AQFPWELARY VGGIENVKIN LTLRIYSQKW
HVYAGLAILN PYAKEQIRQY AQSVTDLYKL MLGGHEKEFR ERVIGAGKKV FGNQPFDGEL
LLKDEILDRF SLGKKPETPM PNNHLSLLAM VDCWSCLNIV PYDHMICSTP LFRLWLGVTE
YLFRKPALLD DVCRIAIEDN TFRSDDLEFT FAARGWSDAV SFGDFEGWKD RFVSTQKFFE
PRFPDATKVG NEMMKTILEN MKNPQACFAR LAVSNSDAQN FLWRFNVLFL NSA
//
