ID   H2NPK2_PONAB            Unreviewed;       571 AA.
AC   H2NPK2; A0A2J8R1L0;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   25-MAY-2022, sequence version 2.
DT   28-JAN-2026, entry version 50.
DE   SubName: Full=PRR35 isoform 1 {ECO:0000313|EMBL:PNJ02404.1};
DE   SubName: Full=Proline rich 35 {ECO:0000313|Ensembl:ENSPPYP00000007827.2};
GN   Name=PRR35 {ECO:0000313|Ensembl:ENSPPYP00000007827.2};
GN   ORFNames=CR201_G0054905 {ECO:0000313|EMBL:PNJ02404.1};
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000007827.2, ECO:0000313|Proteomes:UP000001595};
RN   [1] {ECO:0000313|Ensembl:ENSPPYP00000007827.2, ECO:0000313|Proteomes:UP000001595}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Wilson R.K., Mardis E.;
RT   "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:PNJ02404.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Susie {ECO:0000313|EMBL:PNJ02404.1};
RA   Pollen A., Hastie A., Hormozdiari F., Dougherty M., Liu R., Chaisson M.,
RA   Hoppe E., Hill C., Pang A., Hillier L., Baker C., Armstrong J.,
RA   Shendure J., Paten B., Wilson R., Chao H., Schneider V., Ventura M.,
RA   Kronenberg Z., Murali S., Gordon D., Cantsilieris S., Munson K., Nelson B.,
RA   Raja A., Underwood J., Diekhans M., Fiddes I., Haussler D., Eichler E.;
RT   "High-resolution comparative analysis of great ape genomes.";
RL   Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSPPYP00000007827.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAY-2025) to UniProtKB.
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DR   EMBL; NDHI03003828; PNJ02404.1; -; Genomic_DNA.
DR   AlphaFoldDB; H2NPK2; -.
DR   STRING; 9601.ENSPPYP00000007827; -.
DR   Ensembl; ENSPPYT00000008154.2; ENSPPYP00000007827.2; ENSPPYG00000006912.2.
DR   eggNOG; KOG2177; Eukaryota.
DR   GeneTree; ENSGT00530000063870; -.
DR   HOGENOM; CLU_333144_0_0_1; -.
DR   OMA; WKPGMGG; -.
DR   Proteomes; UP000001595; Chromosome 16.
DR   InterPro; IPR039363; ZNF750.
DR   InterPro; IPR039064; ZNF750_Znf.
DR   PANTHER; PTHR14678:SF2; PROLINE-RICH PROTEIN 35; 1.
DR   PANTHER; PTHR14678; PROLINE-RICH PROTEIN 35-RELATED; 1.
DR   Pfam; PF15269; zf-C2H2_7; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001595}.
FT   DOMAIN          18..68
FT                   /note="Zinc finger protein 750-like zinc finger"
FT                   /evidence="ECO:0000259|Pfam:PF15269"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          78..193
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          308..408
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          476..571
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        16..26
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        165..175
FT                   /note="Gly residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        325..336
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        351..367
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        380..399
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        525..538
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   571 AA;  59538 MW;  5F840D16336C8EB9 CRC64;
     MSREAGSCHV GTGARARSRK PKKPHYIPRP WGKPYNYKCF QCPFTCLEKS HLYNHMKYSL
     CKDSLSLLLD SPDWACRRGS ATPRPRAPTP DRPGESDPGR QPQGAQPTGA APTPDLVVAD
     VCSLHRGGGP KPRAEGSPGP PPPVARATRK GPGPSGLLPE SWKPGMGGDP RGVGAGDMAS
     AGPEGSVPCY PPPAPGEFPE AHSLHLSLLG VNYPLSPGLF SYLGPSLAAA AHVPFLASAS
     PLLPPAAAFP AVQPPQRPTP APRLYYPLLL EHTLGLPAGK AALAKAPVSP RSPSGTLAPG
     LLKVPVPGLG PWPQVTPRDP GQEGELERAA QSDPRRRLSL GSRLELPKAS PSLTRFCSRS
     SLPTGSSVML WPEDREPGSP ETPGPEGPLP PQPRGPVPGS PEHVGEDLTR ALGDYARVEQ
     RLGQLGPAGG LAPRPLREQL GKIRLELLTI HQALERAVRP PDVPLDLSVK RAPAKGPQAL
     GEAWGRPELG PVLTGGTPQP PSMLGPAAPQ PFSGHTTKCE ADSSVPPPGL PLPAPDDPVI
     PGSGWGTCVA TRSSQTPEAV CGLQSPQGAE V
//