ID H6C8I9_EXODN Unreviewed; 403 AA.
AC H6C8I9;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 08-OCT-2025, entry version 41.
DE RecName: Full=Pru domain-containing protein {ECO:0000259|PROSITE:PS51917};
GN ORFNames=HMPREF1120_08378 {ECO:0000313|EMBL:EHY60416.1};
OS Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656) (Black
OS yeast) (Wangiella dermatitidis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=858893 {ECO:0000313|EMBL:EHY60416.1, ECO:0000313|Proteomes:UP000007304};
RN [1] {ECO:0000313|EMBL:EHY60416.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NIH/UT8656 {ECO:0000313|EMBL:EHY60416.1};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Wang Z., Hunicke-Smith S., Szanislo P.J., Earl A., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Exophiala (Wangiella) dermatitidis NIH/UT8656.";
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; JH226136; EHY60416.1; -; Genomic_DNA.
DR RefSeq; XP_009160877.1; XM_009162629.1.
DR AlphaFoldDB; H6C8I9; -.
DR STRING; 858893.H6C8I9; -.
DR GeneID; 20313017; -.
DR VEuPathDB; FungiDB:HMPREF1120_08378; -.
DR eggNOG; KOG3037; Eukaryota.
DR HOGENOM; CLU_041798_4_0_1; -.
DR InParanoid; H6C8I9; -.
DR OMA; RSPQFMQ; -.
DR OrthoDB; 340431at2759; -.
DR Proteomes; UP000007304; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008541; C:proteasome regulatory particle, lid subcomplex; IEA:TreeGrafter.
DR GO; GO:0061133; F:endopeptidase activator activity; IEA:TreeGrafter.
DR GO; GO:0070628; F:proteasome binding; IEA:TreeGrafter.
DR FunFam; 1.10.2020.20:FF:000004; WGS project CABT00000000 data, contig 2.6; 1.
DR Gene3D; 1.10.2020.20; -; 1.
DR Gene3D; 2.30.29.70; Proteasomal ubiquitin receptor Rpn13/ADRM1; 1.
DR InterPro; IPR006773; Rpn13/ADRM1.
DR InterPro; IPR044868; Rpn13/ADRM1_Pru.
DR InterPro; IPR038633; Rpn13/ADRM1_Pru_sf.
DR InterPro; IPR032368; RPN13_DEUBAD.
DR InterPro; IPR038108; RPN13_DEUBAD_sf.
DR PANTHER; PTHR12225; ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN; 1.
DR PANTHER; PTHR12225:SF0; PROTEASOMAL UBIQUITIN RECEPTOR ADRM1; 1.
DR Pfam; PF04683; Rpn13_ADRM1_Pru; 1.
DR Pfam; PF16550; RPN13_C; 1.
DR PROSITE; PS51917; PRU; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW Reference proteome {ECO:0000313|Proteomes:UP000007304}.
FT DOMAIN 1..140
FT /note="Pru"
FT /evidence="ECO:0000259|PROSITE:PS51917"
FT REGION 150..213
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 157..170
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 403 AA; 43596 MW; 9813E8F8FD2D2817 CRC64;
MSIAPIITFK AGLCELDTSS SPPRVKPLPT PGYLYLYAED ELLHLCWRPR TAPLDRPELD
LLMLPGDGSF VPYHPSSAEN PSNPKKPTDG RIYVLKFSSS SQRYLFWLQS RSQHPQGDPA
WFSARDLKLG QIVNNLLQGE EVDVQQQMAE LPKDQNPPDD DDDEPMEEVE GTDHRINRRP
SQGPGAGPDA TGGDFREEGE ESREGGAEGG RAAAATDANA IIQNFIQSLG NSAGNNANNQ
GNESSPQEKL FTTLADLLTP AATIPWIDSA DAKLVDGLLQ YLPPALVTLA QEADDMSALN
TDHASIEAAE QALSLDQKKD ILRRVLRSPQ FSQSLSSLTI ALRDGGLPSI SEALDIPVGN
GGYMRRGGVP LGGGEAVEVF LQGVKDKVTK EKDNEGGDRM DTE
//
