ID H8WGX6_CAEBR Unreviewed; 733 AA.
AC H8WGX6;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 28-JAN-2026, entry version 64.
DE SubName: Full=Protein CBG29115 {ECO:0000313|EMBL:CCG58620.1};
GN ORFNames=CBG29115 {ECO:0000313|EMBL:CCG58620.1,
GN ECO:0000313|WormBase:CBG29115}, CBG_29115
GN {ECO:0000313|EMBL:CCG58620.1};
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238 {ECO:0000313|EMBL:CCG58620.1, ECO:0000313|Proteomes:UP000008549};
RN [1] {ECO:0000313|EMBL:CCG58620.1, ECO:0000313|Proteomes:UP000008549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16 {ECO:0000313|EMBL:CCG58620.1,
RC ECO:0000313|Proteomes:UP000008549};
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
RN [2] {ECO:0000313|EMBL:CCG58620.1, ECO:0000313|Proteomes:UP000008549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16 {ECO:0000313|EMBL:CCG58620.1,
RC ECO:0000313|Proteomes:UP000008549};
RA Ross J.A., Koboldt D.C., Staisch J.E., Chamberlin H.M., Gupta B.P.,
RA Miller R.D., Baird S.E., Haag E.S.;
RT "Caenorhabditis briggsae recombinant inbred line genotypes reveal inter-
RT strain incompatibility and the evolution of recombination.";
RL PLoS Genet. 7:E1002174-E1002174(2011).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004236}.
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DR EMBL; HE600998; CCG58620.1; -; Genomic_DNA.
DR RefSeq; XP_045100881.1; XM_045237674.1.
DR AlphaFoldDB; H8WGX6; -.
DR STRING; 6238.H8WGX6; -.
DR GeneID; 8578980; -.
DR KEGG; cbr:CBG_29115; -.
DR CTD; 8578980; -.
DR WormBase; CBG29115; CBP37855; WBGene00206398; -.
DR eggNOG; KOG4289; Eukaryota.
DR InParanoid; H8WGX6; -.
DR OMA; REVQSHH; -.
DR Proteomes; UP000008549; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 5.
DR FunFam; 2.60.40.60:FF:000104; cadherin-23 isoform X1; 1.
DR FunFam; 2.60.40.60:FF:000135; cadherin-23 isoform X1; 1.
DR FunFam; 2.60.40.60:FF:000080; FAT atypical cadherin 1; 1.
DR FunFam; 2.60.40.60:FF:000365; FlaMIngo (Cadherin plus 7TM domain) homolog; 1.
DR Gene3D; 2.60.40.60; Cadherins; 5.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR055928; Fmi-1_DUF7505.
DR PANTHER; PTHR24026; FAT ATYPICAL CADHERIN-RELATED; 1.
DR PANTHER; PTHR24026:SF51; PROTOCADHERIN-LIKE WING POLARITY PROTEIN STAN; 1.
DR Pfam; PF00028; Cadherin; 4.
DR Pfam; PF24337; DUF7505; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 5.
DR SUPFAM; SSF49313; Cadherin-like; 5.
DR PROSITE; PS00232; CADHERIN_1; 3.
DR PROSITE; PS50268; CADHERIN_2; 5.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000008549};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..733
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003616312"
FT DOMAIN 166..274
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 302..391
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 392..495
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 496..597
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 598..698
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
SQ SEQUENCE 733 AA; 80759 MW; FC6B1DC8A377AF56 CRC64;
MMLNKIMFLP FFITSSLLLV SALTEDKYYS SEPISVVCKP CAVPSSSFVI WLPASRPPCL
HPGQPIIHWP DSSSSDITSC PIPGFPDSIQ SSQLSLLDDG LLLTKERVCF FDGPIDFHYN
YVCDGQIYQS KMRIGHSVAS MKKLEIRRTK RWARRRNPDA NAVHFQQEKY VKELPEDTPI
ETVIASVKAS HASSQPLYYS MVAPQDSRSQ NLFTLDTVSM SGEIRLAKSM DREVLDKHIL
KVSVTAYERV DPTISASTTV VVHVLDVQDN SPIFEKDSYF GEIREDAPVS LFNSSFTPIS
IGTTVLSVFA RDLDSEENGE VEYSLGEGNG KNLLAINSKS GVIQTAAPLD RETLSLIRLD
VIASDKGIPK KESKALVEIT VLDVNDNAPV FASDSYNITI LENITLPTVI ATVKATDEDF
GTNGKVHYSM ASSSGIGGLT IDYSSGEVTL RERIDAKNSP ITAIIRAKDG AQPALSSTVS
LTIHVVDIND HAPTLIAAQK MITLEENVAI GEEVGRVYAI DEDSGPNGII RYSIEGSEDF
IIDEDSGVIK TTKLLDRETT ARYSLKVTAR DMGTPPLNTS TTMTVVLKDI NDNAPIFDKK
EYNVTISEEM PRGSQIIKWK AVDNDEDQKI TYRIEEADRD VFSILDIGDQ GAILSVSGQL
NKQDHKIRVE VSATDQGGLQ GRCVVNVFID DVNSAPYFND HPFSVKIPEH SPIGYPVISM
KVCILLMVFD FNF
//
