ID H8Z0A4_9GAMM Unreviewed; 353 AA.
AC H8Z0A4;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 02-APR-2025, entry version 37.
DE SubName: Full=Sialic acid synthase {ECO:0000313|EMBL:EIC22312.1};
GN ORFNames=Thi970DRAFT_02565 {ECO:0000313|EMBL:EIC22312.1};
OS Thiorhodovibrio frisius.
OC Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
OC Chromatiales; Chromatiaceae; Thiorhodovibrio.
OX NCBI_TaxID=631362 {ECO:0000313|EMBL:EIC22312.1, ECO:0000313|Proteomes:UP000002964};
RN [1] {ECO:0000313|Proteomes:UP000002964}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=970 {ECO:0000313|Proteomes:UP000002964};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Land M.L., Hauser L., Vogl K., Liu Z., Overmann J.,
RA Frigaard N.-U., Bryant D.A., Woyke T.J.;
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EIC22312.1, ECO:0000313|Proteomes:UP000002964}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=970 {ECO:0000313|EMBL:EIC22312.1,
RC ECO:0000313|Proteomes:UP000002964};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Zhang X., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Vogl K., Liu Z.,
RA Overmann J., Frigaard N.-U., Bryant D., Woyke T.;
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; JH603169; EIC22312.1; -; Genomic_DNA.
DR RefSeq; WP_009149033.1; NZ_CP121471.1.
DR AlphaFoldDB; H8Z0A4; -.
DR STRING; 631362.Thi970DRAFT_02565; -.
DR eggNOG; COG2089; Bacteria.
DR HOGENOM; CLU_040465_0_1_6; -.
DR Proteomes; UP000002964; Unassembled WGS sequence.
DR GO; GO:0047444; F:N-acylneuraminate-9-phosphate synthase activity; IEA:TreeGrafter.
DR GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR GO; GO:0070085; P:glycosylation; IEA:TreeGrafter.
DR CDD; cd11615; SAF_NeuB_like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 3.90.1210.10; Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain; 1.
DR InterPro; IPR006190; AFP_Neu5c_C.
DR InterPro; IPR036732; AFP_Neu5c_C_sf.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR013132; Neu5Ac_N.
DR InterPro; IPR051690; Nonulosonic_Acid_Synth.
DR InterPro; IPR013974; SAF.
DR PANTHER; PTHR42966; N-ACETYLNEURAMINATE SYNTHASE; 1.
DR PANTHER; PTHR42966:SF1; SIALIC ACID SYNTHASE; 1.
DR Pfam; PF03102; NeuB; 1.
DR Pfam; PF08666; SAF; 1.
DR SMART; SM00858; SAF; 1.
DR SUPFAM; SSF51269; AFP III-like domain; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS50844; AFP_LIKE; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002964}.
FT DOMAIN 296..353
FT /note="AFP-like"
FT /evidence="ECO:0000259|PROSITE:PS50844"
SQ SEQUENCE 353 AA; 39703 MW; 6788FF2DE2E5C659 CRC64;
MKLTEIIVSP NAKTPFPTPP YLIAEAGVNH EGNMDLAYRL INEAKEGGAD AIKFQTYKAE
TLAAKESPAY WDLTQEPTPS QYELFQKYDK FWKTEYEALA RHCQTVGIEF LSTPFDLASA
RFLNDLMSVF KIASSDLNNK PLIDALCSYG KPILLSTGAA HLWEIEQTLS WIDTQGNPVA
LLHCILNYPT EDSNANLAMI PTLARKFPER VIGYSDHTLP KDMKTLEVAT LLGAQILEKH
FTYDKTRPGN DHYHAMDKAD LQRFHGRMNR LLPLLGNPRK QPLPSEAPAR AYARRSLVAA
RAIPAGKRID PADLTWKRPA TGIDPRDYDQ LLGQMAAVEI AADHILQWNL FRD
//
