ID I0HDN8_ACTM4 Unreviewed; 579 AA.
AC I0HDN8;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 28-JAN-2026, entry version 64.
DE SubName: Full=Putative selenocysteine-specific translation elongation factor {ECO:0000313|EMBL:BAL91125.1};
GN OrderedLocusNames=AMIS_59050 {ECO:0000313|EMBL:BAL91125.1};
OS Actinoplanes missouriensis (strain ATCC 14538 / DSM 43046 / CBS 188.64 /
OS JCM 3121 / NBRC 102363 / NCIMB 12654 / NRRL B-3342 / UNCC 431).
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=512565 {ECO:0000313|EMBL:BAL91125.1, ECO:0000313|Proteomes:UP000007882};
RN [1] {ECO:0000313|EMBL:BAL91125.1, ECO:0000313|Proteomes:UP000007882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14538 / DSM 43046 / CBS 188.64 / JCM 3121 / NBRC 102363 /
RC NCIMB 12654 / NRRL B-3342 / UNCC 431
RC {ECO:0000313|Proteomes:UP000007882};
RA Ohnishi Y., Ishikawa J., Sekine M., Hosoyama A., Harada T., Narita H.,
RA Hata T., Konno Y., Tutikane K., Fujita N., Horinouchi S., Hayakawa M.;
RT "Complete genome sequence of Actinoplanes missouriensis 431 (= NBRC
RT 102363).";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; AP012319; BAL91125.1; -; Genomic_DNA.
DR RefSeq; WP_014446013.1; NC_017093.1.
DR AlphaFoldDB; I0HDN8; -.
DR STRING; 512565.AMIS_59050; -.
DR KEGG; ams:AMIS_59050; -.
DR PATRIC; fig|512565.3.peg.5901; -.
DR eggNOG; COG3276; Bacteria.
DR HOGENOM; CLU_023030_1_1_11; -.
DR OrthoDB; 9803139at2; -.
DR Proteomes; UP000007882; Chromosome.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:BAL91125.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000007882}.
FT DOMAIN 1..170
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 579 AA; 61494 MW; 156F976B460BBE57 CRC64;
MFVVATAGHV DHGKSTVVRA LTGMEPDRWA EERRRGMTID LGFAWTTLDS GATVAFVDVP
GHERFVPNML AGIGPVPAAM IVVAADEGWM PQSAEHLAAL HALDVRHGLL VVTRSDLAAP
GPALRDATER IAGSSLGAVE AVTVSGRTGA GLPDLRAALR RLTDRLPPPV TDEPVRLWID
RSFTIKGAGT VVTGTLGGGV LTRGDELELV GTRVRIRGLQ TLGSPAGRVE AVARVAVNLR
GTDRGAITRG TALLTPGRFR HTDLIDVRGH GDPVTGLPAT IMLHIGSAAV PVRVRPLGPD
TARLRLSRPL PLRIGDRALI RDPGRHHVAG GVTILDVAPP PLTRRGAASA RAEELAGMDG
AADPVAELRR RRLISRAELA GMGVPVDAIA PVTGEWLADP EHWAALRRRL VEEVGSYATE
QPLEPGAPLE ALRHRLDLPD RALVEALVSP PLTSRSGRVT RGTAEIPEML MKAVNQAFAG
AEPFTAPEAT RLTQLGLGPR QIAAAARAGL LIRLADTVVL APEAPSRAAE ILAGLPQPFT
MSEAKNALRT TRRVAVPLLE FLDRKGITRR LPDDRRETT
//
