ID I1I9R8_BRADI Unreviewed; 498 AA.
AC I1I9R8;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 28-JAN-2026, entry version 65.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN Name=LOC100821416 {ECO:0000313|EnsemblPlants:KQJ99511};
GN ORFNames=BRADI_3g43630v3 {ECO:0000313|EMBL:KQJ99511.1};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EnsemblPlants:KQJ99511};
RN [1] {ECO:0000313|EMBL:KQJ99511.1, ECO:0000313|EnsemblPlants:KQJ99511}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQJ99511.1}, and cv. Bd21
RC {ECO:0000313|EnsemblPlants:KQJ99511};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:KQJ99511.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQJ99511.1};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQJ99511}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQJ99511};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR EMBL; CM000882; KQJ99511.1; -; Genomic_DNA.
DR RefSeq; XP_003572534.1; XM_003572486.4.
DR AlphaFoldDB; I1I9R8; -.
DR STRING; 15368.I1I9R8; -.
DR EnsemblPlants; KQJ99511; KQJ99511; BRADI_3g43630v3.
DR GeneID; 100821416; -.
DR Gramene; KQJ99511; KQJ99511; BRADI_3g43630v3.
DR KEGG; bdi:100821416; -.
DR eggNOG; KOG0167; Eukaryota.
DR HOGENOM; CLU_032955_0_0_1; -.
DR OMA; FHDVPQM; -.
DR OrthoDB; 655609at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000008810; Chromosome 3.
DR ExpressionAtlas; I1I9R8; baseline.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR23315; U BOX DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR23315:SF260; U-BOX DOMAIN-CONTAINING PROTEIN 73; 1.
DR Pfam; PF04564; U-box; 1.
DR SMART; SM00504; Ubox; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51698; U_BOX; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008810};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 122..182
FT /note="U-box"
FT /evidence="ECO:0000259|PROSITE:PS51698"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..25
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 498 AA; 55417 MW; A5ED5B1746204330 CRC64;
MNSPRSAARS VRQQQAPSDV VSTSGLVPVQ AARTGIHKKD SSKQQPVVHT RSEFAATMQS
ALVKIQEAAA AGSKGEAAFA EMEQAMTGLM AVSYKEAEPA KLPRVFATRW AQDDANPLME
NVMDDPVTLA SGYSVDQTYY QWFVSQKNTC PVSGHSLPHS ISVPNHLLRD MIAAWCLDHS
KLAPSTTADI LSVPWIPPSE EQIQVILEKL SGSSGPPKET LHLIQLMSKT SKGVQPCLEK
WPDLAAVLLD LKKKWKLLWT PDLEEERITI ILNLSMHRPN REILAEQRKL PGVLLKVIEK
ADSLGSSASL LAMVASIIFL LSEFGMFRKK MLDIRGMKML RDLLKIEDVV VRKESGTAIL
ALCTDEEGKT LAEDYNVADT LLECFMVTDE FLLLLERLPK SPHALDKICD RAVEWVNIIM
GEHASGMVTS RGIHSAISLI SIIAERDVGK LKVKNLEDFK ERLRELTSKR MPMQTMFLVD
RIMKTLSEMF PAHSQLQN
//
