ID J3K7X5_COCIM Unreviewed; 993 AA.
AC J3K7X5;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 2.
DT 02-APR-2025, entry version 50.
DE SubName: Full=Cytokinesis regulator {ECO:0000313|EMBL:EAS30849.3};
GN ORFNames=CIMG_06328 {ECO:0000313|EMBL:EAS30849.3};
OS Coccidioides immitis (strain RS) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=246410 {ECO:0000313|EMBL:EAS30849.3, ECO:0000313|Proteomes:UP000001261};
RN [1] {ECO:0000313|Proteomes:UP000001261}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
RN [2] {ECO:0000313|Proteomes:UP000001261}
RP GENOME REANNOTATION.
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
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DR EMBL; GG704912; EAS30849.3; -; Genomic_DNA.
DR RefSeq; XP_001242432.2; XM_001242431.2.
DR AlphaFoldDB; J3K7X5; -.
DR STRING; 246410.J3K7X5; -.
DR GeneID; 4561804; -.
DR KEGG; cim:CIMG_06328; -.
DR VEuPathDB; FungiDB:CIMG_06328; -.
DR InParanoid; J3K7X5; -.
DR OMA; DWGEGSL; -.
DR OrthoDB; 19159at2759; -.
DR Proteomes; UP000001261; Unassembled WGS sequence.
DR GO; GO:1990334; C:Bfa1-Bub2 complex; IEA:InterPro.
DR GO; GO:0044732; C:mitotic spindle pole body; IEA:TreeGrafter.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0031578; P:mitotic spindle orientation checkpoint signaling; IEA:TreeGrafter.
DR InterPro; IPR034586; Bfa1/Byr4.
DR PANTHER; PTHR35140; MITOTIC CHECK POINT PROTEIN BFA1; 1.
DR PANTHER; PTHR35140:SF1; MITOTIC CHECK POINT PROTEIN BFA1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001261}.
FT REGION 44..68
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 212..271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 327..372
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 398..652
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 680..801
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 912..934
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..68
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 228..240
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 409..418
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 461..487
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..503
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 519..539
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 580..589
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 607..617
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 638..647
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 711..720
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 925..934
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 993 AA; 108569 MW; ED51D22254DEB5E5 CRC64;
MDISPLRLRR PEDEAIECWD DDEDLQCGDE IYFRTVSSAT SVTGCSVRPS GHRDSISSRR
SCRSDRESNY GDEESWQLLL NDQDEFGTDD AIASAKNAGI PIPNGIPRSA LLGGTIKRLG
GRKGKKALGD DWSEDLDLAG LSGEIQLRFK HEATSPESLL HLSSLPTSPS KSRELEYFTD
IINHPPAPKQ QLFNDLDKFK DTEEDASFDD VPTIKLGKSR PPPISNPFAA STATEPGTQD
DNMETDLVLP SDGEPLRLST RRETSKTPDA FGDEFDAEWA EGSIGVRFGG TKREGFSTRS
STVSALSPSV SSCLTAESDD EGFNDFVLPD GPLDLGKSLQ KRQESALPVD LDFPPEPEAS
KQPDPAADDF FSGIEIGDGE LFDTEKLTLN RNIKRKVERP ASPARRGATT ITFTSRTPGT
RIPRLSDRPH STQLEPVSES GAPVSKFVRP ASRLSGHATH SSLSNISISS AGSASSNPPT
RRPSSSRSSK DTIQSTSTNS QLLKTKRSIP GLRNYNAGMA STLQRSPGRQ ESNLKTRATV
SPRPKTPVNQ STAETRLGPQ RRHHVPFIPA GASPNQSHHV SLKTSRHFRR ADSDSSGDMF
THHRSNSRVS SSSALSDTTR RGSTDLPTGS FTAAAKHAVT KPNRKRHFGD GTELDIFDDL
PTSATAESKY VKVPIKKGPP RALRNRLSQS GIPLPCKTET TGSSLPTSPP HQDHTPRFAR
DTNASRNARE QRIASMTHNQ RERENGPLTP ISVNWRSPPF SRPPSSPTMV KSRPGHKHRD
SISRPHLIKP MGSGVHEPKS VKGMKYNPTL YRWEGNETAT AAFDPPALGT PPKSTLALIS
NIGGISGAQV VGSMVFDPQR MCWLKLASPG KTGATIPPEE DDVFAGLEDL DDRPQKSNTT
SRIASAVCDI EANDPLTGDD KSGDSSDDWP ITEEFDVGPE FIKRQRAEEE KWRRKVSKWA
SGDRNKLGDS WRWAIRDLVK TDAPIDIPLS YKR
//
