ID J5RGL9_SACK1 Unreviewed; 389 AA.
AC J5RGL9;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 05-FEB-2025, entry version 36.
DE SubName: Full=CBS2-like protein {ECO:0000313|EMBL:EJT41501.1};
GN Name=YDR197W {ECO:0000313|EMBL:EJT41501.1};
GN Synonyms=SKDI04G4180 {ECO:0000313|EMBL:CAI4058479.1};
GN ORFNames=SKDI_04G4180 {ECO:0000313|EMBL:CAI4058479.1}, SKUD_191808
GN {ECO:0000313|EMBL:EJT41501.1};
OS Saccharomyces kudriavzevii (strain ATCC MYA-4449 / AS 2.2408 / CBS 8840 /
OS NBRC 1802 / NCYC 2889) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=226230 {ECO:0000313|EMBL:EJT41501.1, ECO:0000313|Proteomes:UP000002753};
RN [1] {ECO:0000313|EMBL:EJT41501.1, ECO:0000313|Proteomes:UP000002753}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4449 / AS 2.2408 / CBS 8840 / NBRC 1802 / NCYC 2889
RC {ECO:0000313|Proteomes:UP000002753}, and IFO 1802
RC {ECO:0000313|EMBL:EJT41501.1};
RX PubMed=12775844; DOI=10.1126/science.1084337;
RA Cliften P.F., Sudarsanam P., Desikan A., Fulton L., Fulton B., Majors J.,
RA Waterston R., Cohen B.A., Johnston M.;
RT "Finding functional features in Saccharomyces genomes by phylogenetic
RT footprinting.";
RL Science 301:71-76(2003).
RN [2] {ECO:0000313|EMBL:EJT41501.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=IFO 1802 {ECO:0000313|EMBL:EJT41501.1};
RA Cliften P.F., Johnston M.;
RL Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000002753}
RP GENOME REANNOTATION.
RC STRAIN=ATCC MYA-4449 / AS 2.2408 / CBS 8840 / NBRC 1802 / NCYC 2889
RC {ECO:0000313|Proteomes:UP000002753};
RX PubMed=22384314; DOI=10.1534/g3.111.000273;
RA Scannell D.R., Zill O.A., Rokas A., Payen C., Dunham M.J., Eisen M.B.,
RA Rine J., Johnston M., Hittinger C.T.;
RT "The awesome power of yeast evolutionary genetics: New genome sequences and
RT strain resources for the Saccharomyces sensu stricto genus.";
RL G3 (Bethesda) 1:11-25(2011).
RN [4] {ECO:0000313|EMBL:EJT41501.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=IFO 1802 {ECO:0000313|EMBL:EJT41501.1};
RA Cliften P., Hittinger C.T., Wang B., Sudarsanam P., Desikan A., Fulton L.,
RA Fulton B., Majors J., Waterston R., Cohen B.A., Johnston M.;
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|EMBL:CAI4058479.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=IFO1802 {ECO:0000313|EMBL:CAI4058479.1};
RA Byrne P K.;
RL Submitted (OCT-2022) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; OX365899; CAI4058479.1; -; Genomic_DNA.
DR EMBL; AACI03002015; EJT41501.1; -; Genomic_DNA.
DR STRING; 226230.J5RGL9; -.
DR HOGENOM; CLU_031468_10_2_1; -.
DR OrthoDB; 73846at2759; -.
DR Proteomes; UP000002753; Unassembled WGS sequence.
DR Proteomes; UP001162087; Chromosome 4.
DR GO; GO:0005739; C:mitochondrion; IEA:TreeGrafter.
DR GO; GO:0008677; F:2-dehydropantoate 2-reductase activity; IEA:TreeGrafter.
DR GO; GO:0050661; F:NADP binding; IEA:TreeGrafter.
DR Gene3D; 1.10.1040.10; N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR050838; Ketopantoate_reductase.
DR InterPro; IPR013752; KPA_reductase.
DR PANTHER; PTHR43765; 2-DEHYDROPANTOATE 2-REDUCTASE-RELATED; 1.
DR PANTHER; PTHR43765:SF4; CYTOCHROME B TRANSLATIONAL ACTIVATOR PROTEIN CBS2; 1.
DR Pfam; PF08546; ApbA_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002753}.
FT DOMAIN 247..375
FT /note="Ketopantoate reductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08546"
SQ SEQUENCE 389 AA; 45223 MW; 1D823D70D3F3C611 CRC64;
MSNPIPRVYF LGNSSMTYLL ALRIAQLPSQ PKVPSIVLLL NDQKKLNRFL SNDSKIVVKS
NSSDKEIHHR QFMASCVPPI LNNSEIAPIE NLIISDASSK FITAQLSKYS RSLKPETNIL
FLNPSLNLLE YLHRYRWRSD QTRPNLFMGF TSPVEIGTIH QEFQLVIKMK ERMKFHIAKI
DDFPPMGHVY RKAGPPLIDD RPKNEKENNT LYKLFREMSK LRSGIGSKLV NFDLIIHTFH
DLFFIELENL IIESCTEPLL AVYDCVFKKE LLKVPGAQDI IHKLIKEQLS IIDQSYSSLK
NYPNYSVIFE EERMFNLVIR DLKVNGHKRA KLAQSLRQLN QTNIDELNGY FVTLGKYKKC
NCRWNEMILT LIKGKWSIAK QKALDYHYL
//
