ID J7S2Y3_HUIN7 Unreviewed; 454 AA.
AC J7S2Y3;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 28-JAN-2026, entry version 49.
DE RecName: Full=DBF4-type domain-containing protein {ECO:0000259|PROSITE:PS51265};
GN Name=KNAG0J02260 {ECO:0000313|EMBL:CCK72307.1};
GN OrderedLocusNames=KNAG_0J02260 {ECO:0000313|EMBL:CCK72307.1};
OS Huiozyma naganishii (strain ATCC MYA-139 / BCRC 22969 / CBS 8797 / KCTC
OS 17520 / NBRC 10181 / NCYC 3082 / Yp74L-3) (Yeast) (Kazachstania
OS naganishii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Huiozyma.
OX NCBI_TaxID=1071383 {ECO:0000313|EMBL:CCK72307.1, ECO:0000313|Proteomes:UP000006310};
RN [1] {ECO:0000313|EMBL:CCK72307.1, ECO:0000313|Proteomes:UP000006310}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC 22969 / KCTC 17520
RC / NBRC 10181 / NCYC 3082 {ECO:0000313|Proteomes:UP000006310};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., Oheigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
RN [2] {ECO:0000313|Proteomes:UP000006310}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC 22969 / KCTC 17520
RC / NBRC 10181 / NCYC 3082 {ECO:0000313|Proteomes:UP000006310};
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Genome sequence of Kazachstania naganishii.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; HE978323; CCK72307.1; -; Genomic_DNA.
DR RefSeq; XP_022466552.1; XM_022610236.1.
DR AlphaFoldDB; J7S2Y3; -.
DR STRING; 1071383.J7S2Y3; -.
DR GeneID; 34528062; -.
DR KEGG; kng:KNAG_0J02260; -.
DR eggNOG; KOG4139; Eukaryota.
DR HOGENOM; CLU_602785_0_0_1; -.
DR OMA; PFMEHES; -.
DR OrthoDB; 21380at2759; -.
DR Proteomes; UP000006310; Chromosome 10.
DR GO; GO:0031431; C:Dbf4-dependent protein kinase complex; IEA:TreeGrafter.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0043539; F:protein serine/threonine kinase activator activity; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0010571; P:positive regulation of nuclear cell cycle DNA replication; IEA:TreeGrafter.
DR GO; GO:1901987; P:regulation of cell cycle phase transition; IEA:TreeGrafter.
DR CDD; cd00027; BRCT; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 6.10.250.3410; DBF zinc finger; 1.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR013939; Regulatory_Dfp1/Him1.
DR InterPro; IPR051590; Replication_Regulatory_Kinase.
DR InterPro; IPR006572; Znf_DBF.
DR InterPro; IPR038545; Znf_DBF_sf.
DR PANTHER; PTHR15375; ACTIVATOR OF S-PHASE KINASE-RELATED; 1.
DR PANTHER; PTHR15375:SF26; PROTEIN CHIFFON; 1.
DR Pfam; PF08630; Dfp1_Him1_M; 1.
DR Pfam; PF07535; zf-DBF; 1.
DR SMART; SM00586; ZnF_DBF; 1.
DR PROSITE; PS51265; ZF_DBF4; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000006310};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00600}.
FT DOMAIN 405..454
FT /note="DBF4-type"
FT /evidence="ECO:0000259|PROSITE:PS51265"
FT REGION 339..374
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 342..352
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 454 AA; 52703 MW; 2E2C6E7A2783C7B1 CRC64;
MDGELDEQVV DILRANKSIE DFIKSGKSSQ LICEGDTILE GSISNDSFKT KTKWDSLIEW
QREWRGKLRD RRTNLVHLNE NVPKKTPLTV KKNYAKQRLI YKKKFQKFGA EVVPTFHSKV
NFLVLNTDAD TKPIIKNPTV KIWNLDKTSR FFQRLEIDAK KMATAEEDEI GERNSDVQYF
DKDPHVYLYD ILQDYRPLIC LRWTIEELNS KDDLPYPTLT SLGSYGACPF NRRNKSSETN
HNTVRKRYLR DAFNKKYARK LKILYQKQAK PAESLLPAHY DEVACLEIPH NSRDSSKLFN
ELESRMLKRR QSSNFKFMSF TERDDGMVRM KADTGVTRDE LADIYEEDDS DDDRYTNSTS
ETEAGSDEKP LSSSCNFQTR TDLVNGVNAS IHTISDTKCV ELSSAPKEYN YCENCSMKYN
DLKEHRNTVS HTEFSNDNSK FAVLDAFLSR FVKS
//
