ID J8PQ43_SACAR Unreviewed; 705 AA.
AC J8PQ43;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 18-JUN-2025, entry version 42.
DE SubName: Full=Dbf4p {ECO:0000313|EMBL:EJS44265.1};
GN ORFNames=SU7_0607 {ECO:0000313|EMBL:EJS44265.1};
OS Saccharomyces arboricola (strain H-6 / AS 2.3317 / CBS 10644) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=1160507 {ECO:0000313|EMBL:EJS44265.1, ECO:0000313|Proteomes:UP000006968};
RN [1] {ECO:0000313|EMBL:EJS44265.1, ECO:0000313|Proteomes:UP000006968}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H-6 / AS 2.3317 / CBS 10644
RC {ECO:0000313|Proteomes:UP000006968};
RX PubMed=23368932; DOI=10.1186/1471-2164-14-69;
RA Liti G., Nguyen Ba A.N., Blythe M., Mueller C.A., Bergstroem A.,
RA Cubillos F.A., Dafhnis-Calas F., Khoshraftar S., Malla S., Mehta N.,
RA Siow C.C., Warringer J., Moses A.M., Louis E.J., Nieduszynski C.A.;
RT "High quality de novo sequencing and assembly of the Saccharomyces
RT arboricolus genome.";
RL BMC Genomics 14:69-69(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJS44265.1}.
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DR EMBL; ALIE01000041; EJS44265.1; -; Genomic_DNA.
DR AlphaFoldDB; J8PQ43; -.
DR HOGENOM; CLU_023948_0_0_1; -.
DR OrthoDB; 21380at2759; -.
DR Proteomes; UP000006968; Chromosome IV.
DR GO; GO:0031431; C:Dbf4-dependent protein kinase complex; IEA:TreeGrafter.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0043539; F:protein serine/threonine kinase activator activity; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0010571; P:positive regulation of nuclear cell cycle DNA replication; IEA:TreeGrafter.
DR GO; GO:1901987; P:regulation of cell cycle phase transition; IEA:TreeGrafter.
DR FunFam; 3.40.50.10190:FF:000089; DDK kinase regulatory subunit DBF4; 1.
DR FunFam; 6.10.250.3410:FF:000001; Protein DBF4 homolog A; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 6.10.250.3410; DBF zinc finger; 1.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR055116; DBF4_BRCT.
DR InterPro; IPR013939; Regulatory_Dfp1/Him1.
DR InterPro; IPR051590; Replication_Regulatory_Kinase.
DR InterPro; IPR006572; Znf_DBF.
DR InterPro; IPR038545; Znf_DBF_sf.
DR PANTHER; PTHR15375; ACTIVATOR OF S-PHASE KINASE-RELATED; 1.
DR PANTHER; PTHR15375:SF26; PROTEIN CHIFFON; 1.
DR Pfam; PF22437; DBF4_BRCT; 1.
DR Pfam; PF08630; Dfp1_Him1_M; 1.
DR Pfam; PF07535; zf-DBF; 1.
DR SMART; SM00586; ZnF_DBF; 1.
DR PROSITE; PS51265; ZF_DBF4; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000006968};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00600}.
FT DOMAIN 655..704
FT /note="DBF4-type"
FT /evidence="ECO:0000259|PROSITE:PS51265"
FT COILED 424..454
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 705 AA; 80753 MW; EA4F45DD125E07BB CRC64;
MVSPTKMIIR SPLKETDTNL KHKNGVTVSA ATATAHLNAF SNDNNSINNH NTTESYPKKR
SLERLELQQQ QQHLQEKKRA KLERARSIEG AVQVSKGTGL KNVEPRVTPK ELLEWQTNWK
KIMKRDSRIY FDITDDVEMN TSNKSKMDKR RDLLKRGFLT LGAQITQFFD TTVTIVITRR
SVENIYLLKD TDILSRAKKN YMKVWSYEKA ARFLKNLDVD LDHLSKTKSA SLATPTLSNL
LHNEKLYGPT DRDPRTRRDD IHYFKYPHVY LYDLWQTWAP IITLEWKPQE LTNLEELPYP
ILKLGSFGRC PFIGDKNYDE SSYKRVVKRY SRDKANKKYA LQLRVLFQYH ADTLMNTSSV
NDQTKNLIFI PHTCNDSTKS FKKWMQEKAK TFKKDALKKP EDEAVQEVHD NNDILTNNQN
SILVKEIENG KDGLKEEKEN KQSVVDESKK YLQRKEPLAT PKLNHPILAT FTRQETEEVP
DDLCTLKTKS RQAFEIKASG AHQSNDVATS FGNGLGPTRA SVMSKNMKSL SRLMVDRKLG
VKQPNGNYKN YTTAKTTAME TLNGSKHGLD VNAFQKDETR SKTITKDNTI RTEPNIKVQD
LPTTAIKSAS TNPKFNNETK ISITESVTAS KKITTSTNTT LHPNAPTTLP VKKEALKNSG
YCENCRVKYD SLEQHIVSEK HLSFAENDLN FEAIDSLIES LKFQI
//
