ID K0YJ34_9ACTN Unreviewed; 249 AA.
AC K0YJ34;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 02-APR-2025, entry version 42.
DE SubName: Full=ComEA protein {ECO:0000313|EMBL:EJZ83466.1};
GN ORFNames=HMPREF9451_00971 {ECO:0000313|EMBL:EJZ83466.1};
OS Slackia piriformis YIT 12062.
OC Bacteria; Bacillati; Actinomycetota; Coriobacteriia; Eggerthellales;
OC Eggerthellaceae; Slackia.
OX NCBI_TaxID=742818 {ECO:0000313|EMBL:EJZ83466.1, ECO:0000313|Proteomes:UP000006069};
RN [1] {ECO:0000313|EMBL:EJZ83466.1, ECO:0000313|Proteomes:UP000006069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIT 12062 {ECO:0000313|EMBL:EJZ83466.1,
RC ECO:0000313|Proteomes:UP000006069};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Morotomi M., Walker B.,
RA Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A.,
RA Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J.,
RA McCowen C., Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Slackia piriformis YIT 12062.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJZ83466.1}.
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DR EMBL; ADMD01000007; EJZ83466.1; -; Genomic_DNA.
DR RefSeq; WP_009139185.1; NZ_JH815198.1.
DR AlphaFoldDB; K0YJ34; -.
DR PATRIC; fig|742818.3.peg.1030; -.
DR eggNOG; COG1555; Bacteria.
DR HOGENOM; CLU_052011_1_2_11; -.
DR InParanoid; K0YJ34; -.
DR Proteomes; UP000006069; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0015627; C:type II protein secretion system complex; IEA:TreeGrafter.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0015628; P:protein secretion by the type II secretion system; IEA:TreeGrafter.
DR Gene3D; 1.10.150.280; AF1531-like domain; 1.
DR Gene3D; 3.10.560.10; Outer membrane lipoprotein wza domain like; 1.
DR InterPro; IPR004509; Competence_ComEA_HhH.
DR InterPro; IPR051675; Endo/Exo/Phosphatase_dom_1.
DR InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR InterPro; IPR010994; RuvA_2-like.
DR InterPro; IPR019554; Soluble_ligand-bd.
DR NCBIfam; TIGR00426; competence protein ComEA helix-hairpin-helix repeat region; 1.
DR PANTHER; PTHR21180; ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR21180:SF32; ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE FAMILY DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF12836; HHH_3; 1.
DR Pfam; PF10531; SLBB; 1.
DR SMART; SM00278; HhH1; 2.
DR SUPFAM; SSF142984; Nqo1 middle domain-like; 1.
DR SUPFAM; SSF47781; RuvA domain 2-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006069};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 197..216
FT /note="Helix-hairpin-helix DNA-binding motif class 1"
FT /evidence="ECO:0000259|SMART:SM00278"
FT DOMAIN 227..246
FT /note="Helix-hairpin-helix DNA-binding motif class 1"
FT /evidence="ECO:0000259|SMART:SM00278"
FT REGION 59..93
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 162..184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 79..91
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 163..180
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 249 AA; 25022 MW; 3267BF267B6DDDEC CRC64;
MPFSRSAYNL KSRLHISHIP TPALVGAGVL LIAALAGVAA GFVSFSGKSP TFEVVASEDA
EGSFEAKEGA DASEEGQAAP SSEPSQRSGA DQDSAVLPTL AVHVSGAVAS PGVYELEEGA
RVRDAVEAAG GFAAEASQES VNLARKVSDG EQIFVLTVEE FEASPSSSSP SSGSSDAGAQ
GSSGAGGLVN INTAGLEALD SLPGVGPATA QAILDEREAN GPFASIEDIQ RVSGIGEKKY
EKLKGSICV
//
