ID K8E0P1_9FIRM Unreviewed; 440 AA.
AC K8E0P1;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 18-JUN-2025, entry version 65.
DE SubName: Full=Flagellum-specific ATPase drives type III flagellar export {ECO:0000313|EMBL:CCO09167.1};
DE EC=3.6.3.14 {ECO:0000313|EMBL:CCO09167.1};
GN Name=fliI {ECO:0000313|EMBL:CCO09167.1};
GN ORFNames=DESHY_60339 {ECO:0000313|EMBL:CCO09167.1};
OS Desulforamulus hydrothermalis Lam5 = DSM 18033.
OC Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Peptococcaceae;
OC Desulforamulus.
OX NCBI_TaxID=1121428 {ECO:0000313|EMBL:CCO09167.1, ECO:0000313|Proteomes:UP000009315};
RN [1] {ECO:0000313|EMBL:CCO09167.1, ECO:0000313|Proteomes:UP000009315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lam5 / DSM 18033 {ECO:0000313|Proteomes:UP000009315};
RX PubMed=23405336; DOI=10.1128/genomeA.00114-12;
RA Amin O., Fardeau M.L., Valette O., Hirschler-Rea A., Barbe V., Medigue C.,
RA Vacherie B., Ollivier B., Bertin P.N., Dolla A.;
RT "Genome Sequence of the Sulfate-Reducing Bacterium Desulfotomaculum
RT hydrothermale Lam5(T).";
RL Genome Announc. 1:e00114-e00112(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O + cellular proteinSide 1 = ADP + phosphate +
CC cellular proteinSide 2.; EC=7.4.2.8;
CC Evidence={ECO:0000256|ARBA:ARBA00034006};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCO09167.1}.
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DR EMBL; CAOS01000013; CCO09167.1; -; Genomic_DNA.
DR RefSeq; WP_008413033.1; NZ_CAOS01000013.1.
DR AlphaFoldDB; K8E0P1; -.
DR STRING; 1121428.DESHY_60339; -.
DR eggNOG; COG1157; Bacteria.
DR OrthoDB; 9802718at2; -.
DR Proteomes; UP000009315; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0030257; C:type III protein secretion system complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:TreeGrafter.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IEA:InterPro.
DR GO; GO:0030254; P:protein secretion by the type III secretion system; IEA:InterPro.
DR CDD; cd18114; ATP-synt_flagellum-secretory_path_III_C; 1.
DR CDD; cd18117; ATP-synt_flagellum-secretory_path_III_N; 1.
DR CDD; cd01136; ATPase_flagellum-secretory_path_III; 1.
DR FunFam; 3.40.50.12240:FF:000002; Flagellum-specific ATP synthase FliI; 1.
DR Gene3D; 3.40.50.12240; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR020003; ATPase_a/bsu_AS.
DR InterPro; IPR050053; ATPase_alpha/beta_chains.
DR InterPro; IPR004100; ATPase_F1/V1/A1_a/bsu_N.
DR InterPro; IPR000194; ATPase_F1/V1/A1_a/bsu_nucl-bd.
DR InterPro; IPR005714; ATPase_T3SS_FliI/YscN.
DR InterPro; IPR022425; FliI_clade2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR040627; T3SS_ATPase_C.
DR NCBIfam; TIGR03497; FliI_clade2; 1.
DR NCBIfam; TIGR01026; fliI_yscN; 1.
DR PANTHER; PTHR15184; ATP SYNTHASE; 1.
DR PANTHER; PTHR15184:SF9; SPI-1 TYPE 3 SECRETION SYSTEM ATPASE; 1.
DR Pfam; PF00006; ATP-synt_ab; 1.
DR Pfam; PF02874; ATP-synt_ab_N; 1.
DR Pfam; PF18269; T3SS_ATPase_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00152; ATPASE_ALPHA_BETA; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell projection {ECO:0000313|EMBL:CCO09167.1};
KW Cilium {ECO:0000313|EMBL:CCO09167.1};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Flagellum {ECO:0000313|EMBL:CCO09167.1};
KW Hydrolase {ECO:0000313|EMBL:CCO09167.1};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000009315};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 160..341
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 440 AA; 47309 MW; 63E39019B6475648 CRC64;
MQEQVAINLA PYKERVSRAR VIKPIGQVTR VIGLMIEVQG IIARIGEVCD IVVQDAAPVK
AEVVGFRDRH SLLMPLGELR GIYPGSAVVP TGRQLTVKVG RHLLGKVLDG LGRPFNAAAD
EPGEDFPVDN RPPQPLQRQR IQTVLPTGVR AVDGLLTCGR GQRMGIFAGS GVGKSTLLGM
IARHGSADVN VIGLIGERGR EVLEFLEEDL GPAGLAKSVI VAATSDQPAL VRLKGAFVAT
AIAEYFRDQG LDVMLLMDSV TRFAMAQREV GLAVGEPPAT KGYTPSVFAL LPRLLERSGM
GQRGSVTAFY TVLVDGDDLN EPIADAVRGI LDGHIVLTRR LAAANHYPAI DVLQSVSRLM
PELAAEEHKA RAGLLRDLLA TYNQAEDLIN IGAYVKGSNP KIDEAIEKHD SIIRFLKQTP
SEYSSYEETL NQLAALAGRG
//
