ID   L8G341_PSED2            Unreviewed;       242 AA.
AC   L8G341;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   10-JUN-2026, entry version 36.
DE   RecName: Full=Prephenate dehydrogenase (NADP(+)) {ECO:0008006|Google:ProtNLM};
GN   ORFNames=GMDG_02123 {ECO:0000313|EMBL:ELR06406.1};
OS   Pseudogymnoascus destructans (strain ATCC MYA-4855 / 20631-21) (Bat
OS   white-nose syndrome fungus) (Geomyces destructans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Thelebolales; Thelebolaceae; Pseudogymnoascus.
OX   NCBI_TaxID=658429 {ECO:0000313|EMBL:ELR06406.1, ECO:0000313|Proteomes:UP000011064};
RN   [1] {ECO:0000313|Proteomes:UP000011064}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4855 / 20631-21 {ECO:0000313|Proteomes:UP000011064};
RG   The Broad Institute Genome Sequencing Platform;
RA   Cuomo C.A., Blehert D.S., Lorch J.M., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA   Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA   Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA   Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA   Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The genome sequence of Geomyces destructans 20631-21.";
RL   Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GL573196; ELR06406.1; -; Genomic_DNA.
DR   AlphaFoldDB; L8G341; -.
DR   FunCoup; L8G341; 218.
DR   STRING; 658429.L8G341; -.
DR   VEuPathDB; FungiDB:GMDG_02123; -.
DR   HOGENOM; CLU_031403_0_0_1; -.
DR   InParanoid; L8G341; -.
DR   OrthoDB; 1139at34379; -.
DR   Proteomes; UP000011064; Unassembled WGS sequence.
DR   GO; GO:0070403; F:NAD+ binding; IEA:TreeGrafter.
DR   GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:TreeGrafter.
DR   GO; GO:0006571; P:L-tyrosine biosynthetic process; IEA:TreeGrafter.
DR   FunFam; 1.10.3660.10:FF:000002; Prephenate dehydrogenase [NADP(+)]; 1.
DR   Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 2.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR050812; Preph/Arog_dehydrog.
DR   PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR   Pfam; PF27505; 6PGD_Tyr1_C; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 2.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011064}.
SQ   SEQUENCE   242 AA;  28077 MW;  C96E0C8F6B24B0E8 CRC64;
     MGKAWHANAQ FPWEIARYVG GIENVKINLT LRIYSQKWHV YAGLAILNPY AKEQIRQYSQ
     SVTDLFKLML GGNREEFERR IRAAGAAVFD AQKSHHGILL EDEVLDRFSL GKKPDEPTPN
     NHLSLLAMVD CWSRMGIVPY DHMICSTPLF RLWLGVTEYL FRQPALLDDV IRIAIEDNTF
     RSDDLEFTFA ARGWSDCVTF GDFESYKDRF ESTRKFFEPR FADATKVGNE MMKTILMNTM
     RE
//