ID M1SUW2_MORMO Unreviewed; 240 AA.
AC M1SUW2;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 28-JAN-2026, entry version 65.
DE RecName: Full=RNA polymerase sigma factor FliA {ECO:0000256|HAMAP-Rule:MF_00962};
DE AltName: Full=RNA polymerase sigma factor for flagellar operon {ECO:0000256|HAMAP-Rule:MF_00962};
DE AltName: Full=Sigma F {ECO:0000256|HAMAP-Rule:MF_00962};
DE AltName: Full=Sigma-28 {ECO:0000256|HAMAP-Rule:MF_00962};
GN Name=fliA {ECO:0000256|HAMAP-Rule:MF_00962};
GN ORFNames=MU9_1816 {ECO:0000313|EMBL:AGG30862.1};
OS Morganella morganii subsp. morganii KT.
OC Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
OC Enterobacterales; Morganellaceae; Morganella.
OX NCBI_TaxID=1124991 {ECO:0000313|EMBL:AGG30862.1, ECO:0000313|Proteomes:UP000011834};
RN [1] {ECO:0000313|EMBL:AGG30862.1, ECO:0000313|Proteomes:UP000011834}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KT {ECO:0000313|EMBL:AGG30862.1,
RC ECO:0000313|Proteomes:UP000011834};
RX PubMed=23282187;
RA Chen Y.T., Peng H.L., Shia W.C., Hsu F.R., Ken C.F., Tsao Y.M., Chen C.H.,
RA Liu C.E., Hsieh M.F., Chen H.C., Tang C.Y., Ku T.H.;
RT "Whole-genome sequencing and identification of Morganella morganii KT
RT pathogenicity-related genes.";
RL BMC Genomics 13:S4-S4(2012).
CC -!- FUNCTION: Sigma factors are initiation factors that promote the
CC attachment of RNA polymerase to specific initiation sites and are then
CC released. This sigma factor controls the expression of flagella-related
CC genes. {ECO:0000256|HAMAP-Rule:MF_00962}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00962}.
CC -!- SIMILARITY: Belongs to the sigma-70 factor family. FliA subfamily.
CC {ECO:0000256|HAMAP-Rule:MF_00962}.
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DR EMBL; CP004345; AGG30862.1; -; Genomic_DNA.
DR RefSeq; WP_004240062.1; NC_020418.1.
DR AlphaFoldDB; M1SUW2; -.
DR GeneID; 93360871; -.
DR KEGG; mmk:MU9_1816; -.
DR eggNOG; COG1191; Bacteria.
DR HOGENOM; CLU_014793_8_1_6; -.
DR Proteomes; UP000011834; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed RNA polymerase activity; IEA:InterPro.
DR GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:UniProtKB-UniRule.
DR CDD; cd06171; Sigma70_r4; 1.
DR FunFam; 1.10.1740.10:FF:000002; RNA polymerase sigma factor FliA; 1.
DR FunFam; 1.20.140.160:FF:000001; RNA polymerase sigma factor FliA; 1.
DR Gene3D; 1.10.1740.10; -; 1.
DR Gene3D; 1.20.140.160; -; 1.
DR HAMAP; MF_00962; Sigma70_FliA; 1.
DR InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR InterPro; IPR000943; RNA_pol_sigma70.
DR InterPro; IPR007627; RNA_pol_sigma70_r2.
DR InterPro; IPR007624; RNA_pol_sigma70_r3.
DR InterPro; IPR007630; RNA_pol_sigma70_r4.
DR InterPro; IPR012845; RNA_pol_sigma_FliA_WhiG.
DR InterPro; IPR013325; RNA_pol_sigma_r2.
DR InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR InterPro; IPR028617; Sigma70_FliA.
DR NCBIfam; TIGR02479; FliA_WhiG; 1.
DR NCBIfam; NF005413; PRK06986.1; 1.
DR NCBIfam; TIGR02937; sigma70-ECF; 1.
DR PANTHER; PTHR30385:SF7; RNA POLYMERASE SIGMA FACTOR FLIA; 1.
DR PANTHER; PTHR30385; SIGMA FACTOR F FLAGELLAR; 1.
DR Pfam; PF04542; Sigma70_r2; 1.
DR Pfam; PF04539; Sigma70_r3; 1.
DR Pfam; PF04545; Sigma70_r4; 1.
DR PIRSF; PIRSF000770; RNA_pol_sigma-SigE/K; 1.
DR PRINTS; PR00046; SIGMA70FCT.
DR SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 2.
DR PROSITE; PS00715; SIGMA70_1; 1.
DR PROSITE; PS00716; SIGMA70_2; 1.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000313|EMBL:AGG30862.1};
KW Cilium {ECO:0000313|EMBL:AGG30862.1};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_00962};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_00962}; Flagellum {ECO:0000313|EMBL:AGG30862.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000011834};
KW Sigma factor {ECO:0000256|ARBA:ARBA00023082, ECO:0000256|HAMAP-
KW Rule:MF_00962};
KW Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|HAMAP-
KW Rule:MF_00962};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015, ECO:0000256|HAMAP-
KW Rule:MF_00962}.
FT DOMAIN 43..56
FT /note="RNA polymerase sigma-70"
FT /evidence="ECO:0000259|PROSITE:PS00715"
FT DOMAIN 206..232
FT /note="RNA polymerase sigma-70"
FT /evidence="ECO:0000259|PROSITE:PS00716"
FT DNA_BIND 207..226
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00962"
FT REGION 16..88
FT /note="Sigma-70 factor domain-2"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00962"
FT REGION 96..166
FT /note="Sigma-70 factor domain-3"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00962"
FT REGION 185..233
FT /note="Sigma-70 factor domain-4"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00962"
FT MOTIF 43..46
FT /note="Interaction with polymerase core subunit RpoC"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00962"
SQ SEQUENCE 240 AA; 27308 MW; 1F97A6D29AA9553D CRC64;
MSDLYTAEGV INKNSLWERY YPLIRHEALK LQVRLPASVD IDDLIQAGGI GLLHAVERFD
AMQGATFATY AVQRIRGAML DELRGRDWAP RSVRRQAREI TKAVRALEQS LGRAAAEQEI
ADSLQMDIAE YRQVLTDTNN SQLFSYDEWH EIHGESCEPV RDDDDGGNPL GLLVDESLRH
QVVEAIKQLP EREKLVLTLY YQEELNLKEI GAVLEVGESR VSQLHSQAIK RLRARLKSMK
//
