ID M7ZME2_TRIUA Unreviewed; 950 AA.
AC M7ZME2;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 28-JAN-2026, entry version 64.
DE SubName: Full=Disease resistance protein RPM1 {ECO:0000313|EMBL:EMS61282.1};
GN Name=LOC125528840
GN {ECO:0000313|EnsemblPlants:TuG1812S0001191900.01.T01};
GN ORFNames=TRIUR3_12847 {ECO:0000313|EMBL:EMS61282.1};
OS Triticum urartu (Red wild einkorn) (Crithodium urartu).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4572 {ECO:0000313|EMBL:EMS61282.1};
RN [1] {ECO:0000313|EMBL:EMS61282.1, ECO:0000313|Proteomes:UP000015106}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. G1812 {ECO:0000313|Proteomes:UP000015106};
RX PubMed=23535596; DOI=10.1038/nature11997;
RA Ling H.Q., Zhao S., Liu D., Wang J., Sun H., Zhang C., Fan H., Li D.,
RA Dong L., Tao Y., Gao C., Wu H., Li Y., Cui Y., Guo X., Zheng S., Wang B.,
RA Yu K., Liang Q., Yang W., Lou X., Chen J., Feng M., Jian J., Zhang X.,
RA Luo G., Jiang Y., Liu J., Wang Z., Sha Y., Zhang B., Wu H., Tang D.,
RA Shen Q., Xue P., Zou S., Wang X., Liu X., Wang F., Yang Y., An X., Dong Z.,
RA Zhang K., Zhang X., Luo M.C., Dvorak J., Tong Y., Wang J., Yang H., Li Z.,
RA Wang D., Zhang A., Wang J.;
RT "Draft genome of the wheat A-genome progenitor Triticum urartu.";
RL Nature 496:87-90(2013).
RN [2] {ECO:0000313|EnsemblPlants:TuG1812S0001191900.01.T01}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (JUN-2022) to UniProtKB.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; KD098087; EMS61282.1; -; Genomic_DNA.
DR RefSeq; XP_048549229.1; XM_048693272.1.
DR AlphaFoldDB; M7ZME2; -.
DR STRING; 4572.M7ZME2; -.
DR EnsemblPlants; TuG1812S0001191900.01.T01; TuG1812S0001191900.01.T01; TuG1812S0001191900.01.
DR GeneID; 125528840; -.
DR Gramene; TuG1812S0001191900.01.T01; TuG1812S0001191900.01.T01; TuG1812S0001191900.01.
DR KEGG; tua:125528840; -.
DR eggNOG; KOG4658; Eukaryota.
DR OMA; HEWEMIS; -.
DR OrthoDB; 613494at2759; -.
DR Proteomes; UP000015106; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-ARBA.
DR GO; GO:0002758; P:innate immune response-activating signaling pathway; IEA:UniProtKB-ARBA.
DR GO; GO:0009626; P:plant-type hypersensitive response; IEA:UniProtKB-ARBA.
DR CDD; cd14798; RX-CC_like; 1.
DR FunFam; 3.40.50.300:FF:001091; Probable disease resistance protein At1g61300; 1.
DR FunFam; 1.10.10.10:FF:000322; Probable disease resistance protein At1g63360; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR055414; LRR_R13L4/SHOC2-like.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR058922; WHD_DRP.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1167; OS08G0412100 PROTEIN; 1.
DR Pfam; PF23598; LRR_14; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR Pfam; PF23559; WHD_DRP; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000015106};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 11..98
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 191..348
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT DOMAIN 437..508
FT /note="Disease resistance protein winged helix"
FT /evidence="ECO:0000259|Pfam:PF23559"
FT DOMAIN 558..917
FT /note="Disease resistance R13L4/SHOC-2-like LRR"
FT /evidence="ECO:0000259|Pfam:PF23598"
FT REGION 931..950
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 936..950
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 950 AA; 106827 MW; 87E178AF84746B41 CRC64;
MEVVVSASHG VMGPLLGKLA DLLAGKYGRI RGVRGEILSL QAELTSMHAA LKNYTMLEDL
DVQVKAWISL LRELAYDTED CIDKFIRRLG KRRRRGGFKE LLRETTRFLK SLDSRSGIAD
QIDELKARIK HVKELKDCYK LSEIPCSKTE HAAVDPRLCA LFAEEAHLVG VEGPRDDLVK
WMLKEETNNS TKDRKVLSIV GFGGLGKTTL ANEVYRKIHG NFDCQAFVSV SQKPYIKNII
KDVISQVPCQ DGSTKDTSDW DEKKSIAKLR ELLQDKRYLV IVDDIWSTQA WNNIKCAFPY
NNCSSRIITT TRIIDVAKSC CPGSDDRVYE MAALSDLHSK RLFLKRIFGS EDHCPDMLKE
SSNEILKKCG GLPLAIVSIS SLLANRPAVK EEWEKIRRSI GSALENNQSL EGMSKILLLS
YNDLPPNLKT CLLYLSVFPE DYVIDRERLV RRWIAEGFIS EERGQSQQEV AERYFYELVN
KSMVQPEDIG YDGKARACRV HDMMLEIIIS KSNEHNFIIV IGGGQTSLAN RQGFIRRLSI
QHIDHELAHL LAQEDLSHVR SLTVTCSACI KHLPSLAKFE ALRVLDFAGC EGLEKYDMKS
IGKLFHLKYL NFPATRIPKL PSGIVLLRDL ETLHFGATPV EELPTGFAQL TKLQHLIGGG
WTIIPKKIGN MRNLREISGF SVTKSPADVV EDLGNLPGLE EIDIYLNGGE SDEFRRHEEM
LLSSLCKLGS CKLRSLRIRG NDGSLEFLGS WSPLPFTLQE FHMVGDYYFT KVPEWIAPAL
TSLSFLDINL AELTEEGLVT LGELPALLHL VLWFRKIPDD RVIVRGFPSL KQFTIYSNDA
SAYVTFVKGS MPKLKKLDFL INVSMAKTYG FYLGIEHLTC LKQATARLDN KGATPSERKA
AEAVIRVEAG AHPNHPAVTI CEEYQCSEED SEDICGDEKK SKEDGGTDEN
//
