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Database: UniProt
Entry: O34412
LinkDB: O34412
Original site: O34412 
ID   YLBF_BACSU              Reviewed;         149 AA.
AC   O34412;
DT   01-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   29-SEP-2021, entry version 104.
DE   RecName: Full=Regulatory protein YlbF;
GN   Name=ylbF; OrderedLocusNames=BSU14990;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RA   Bertero M., Presecan E., Glaser P., Richou A., Danchin A.;
RT   "Bacillus subtilis chromosomal region downstream nprE.";
RL   Submitted (AUG-1997) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   INVOLVEMENT IN COMPETENCE, AND INVOLVEMENT IN SPORULATION.
RC   STRAIN=168;
RX   PubMed=10712692; DOI=10.1046/j.1365-2958.2000.01779.x;
RA   Tortosa P., Albano M., Dubnau D.;
RT   "Characterization of ylbF, a new gene involved in competence development
RT   and sporulation in Bacillus subtilis.";
RL   Mol. Microbiol. 35:1110-1119(2000).
RN   [4]
RP   ROLE IN FORMATION OF BIOFILMS.
RC   STRAIN=168, and 3610;
RX   PubMed=15175311; DOI=10.1128/jb.186.12.3970-3979.2004;
RA   Branda S.S., Gonzalez-Pastor J.E., Dervyn E., Ehrlich S.D., Losick R.,
RA   Kolter R.;
RT   "Genes involved in formation of structured multicellular communities by
RT   Bacillus subtilis.";
RL   J. Bacteriol. 186:3970-3979(2004).
CC   -!- FUNCTION: Regulates sporulation prior to stage II. Positively controls
CC       the competence regulator ComK at a post-transcriptional level. May
CC       modulate the translation, stability or activity of ComS. May work
CC       together with YmcA to regulate community development.
CC       {ECO:0000269|PubMed:15175311}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
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DR   EMBL; Z98682; CAB11352.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB13372.1; -; Genomic_DNA.
DR   PIR; C69874; C69874.
DR   RefSeq; NP_389382.1; NC_000964.3.
DR   RefSeq; WP_003221370.1; NZ_JNCM01000035.1.
DR   PDB; 6PRK; X-ray; 3.20 A; A=1-121.
DR   PDBsum; 6PRK; -.
DR   SMR; O34412; -.
DR   STRING; 224308.BSU14990; -.
DR   PaxDb; O34412; -.
DR   PRIDE; O34412; -.
DR   EnsemblBacteria; CAB13372; CAB13372; BSU_14990.
DR   GeneID; 64303390; -.
DR   GeneID; 939945; -.
DR   KEGG; bsu:BSU14990; -.
DR   PATRIC; fig|224308.179.peg.1634; -.
DR   eggNOG; COG3679; Bacteria.
DR   OMA; PYQNIKE; -.
DR   PhylomeDB; O34412; -.
DR   BioCyc; BSUB:BSU14990-MONOMER; -.
DR   PRO; PR:O34412; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0030420; P:establishment of competence for transformation; IEA:UniProtKB-KW.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1500.10; -; 1.
DR   InterPro; IPR010368; Com_YlbF.
DR   InterPro; IPR023378; YheA/YmcA-like_dom_sf.
DR   Pfam; PF06133; Com_YlbF; 1.
DR   SUPFAM; SSF158622; SSF158622; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Competence; Cytoplasm; Reference proteome; Sporulation.
FT   CHAIN           1..149
FT                   /note="Regulatory protein YlbF"
FT                   /id="PRO_0000066288"
FT   HELIX           8..22
FT                   /evidence="ECO:0007829|PDB:6PRK"
FT   HELIX           25..39
FT                   /evidence="ECO:0007829|PDB:6PRK"
FT   HELIX           42..63
FT                   /evidence="ECO:0007829|PDB:6PRK"
FT   HELIX           70..86
FT                   /evidence="ECO:0007829|PDB:6PRK"
FT   HELIX           88..116
FT                   /evidence="ECO:0007829|PDB:6PRK"
SQ   SEQUENCE   149 AA;  16914 MW;  F9E273EC4A7800EF CRC64;
     MYATMESVRL QSEAQQLAEM ILQSETAENY RNCYKRLQED EEAGRIIRSF IKIKEQYEDV
     QRFGKYHPDY REISRKMREI KRELDLNDKV ADFKRAENEL QSILDEVSVE IGTAVSEHVK
     VPTGNPYFDG LSSCGGGCGS GGSCGCKVS
//
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