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Database: UniProt
Entry: P12875
LinkDB: P12875
Original site: P12875 
ID   RL14_BACSU              Reviewed;         122 AA.
AC   P12875;
DT   01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1989, sequence version 1.
DT   29-SEP-2021, entry version 141.
DE   RecName: Full=50S ribosomal protein L14 {ECO:0000255|HAMAP-Rule:MF_01367};
GN   Name=rplN {ECO:0000255|HAMAP-Rule:MF_01367}; OrderedLocusNames=BSU01260;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=2508062; DOI=10.1093/nar/17.18.7469;
RA   Henkin T.M., Moon S.H., Mattheakis L.C., Nomura M.;
RT   "Cloning and analysis of the spc ribosomal protein operon of Bacillus
RT   subtilis: comparison with the spc operon of Escherichia coli.";
RL   Nucleic Acids Res. 17:7469-7486(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168 / Marburg / ATCC 6051 / DSM 10 / JCM 1465 / NBRC 13719 / NCIMB
RC   3610 / NRRL NRS-744 / VKM B-501;
RX   PubMed=8635744; DOI=10.1016/0378-1119(95)00757-1;
RA   Suh J.-W., Boylan S.A., Oh S.H., Price C.W.;
RT   "Genetic and transcriptional organization of the Bacillus subtilis spc-
RT   alpha region.";
RL   Gene 169:17-23(1996).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [4] {ECO:0007744|PDB:6HA1, ECO:0007744|PDB:6HA8}
RP   STRUCTURE BY ELECTRON MICROSCOPY (3.10 ANGSTROMS) OF 1-122 WITH AND WITHOUT
RP   VIRGINIAMYCIN M.
RX   PubMed=30126986; DOI=10.1073/pnas.1808535115;
RA   Crowe-McAuliffe C., Graf M., Huter P., Takada H., Abdelshahid M.,
RA   Novacek J., Murina V., Atkinson G.C., Hauryliuk V., Wilson D.N.;
RT   "Structural basis for antibiotic resistance mediated by the Bacillus
RT   subtilis ABCF ATPase VmlR.";
RL   Proc. Natl. Acad. Sci. U.S.A. 115:8978-8983(2018).
CC   -!- FUNCTION: Binds to 23S rRNA. Forms part of two intersubunit bridges in
CC       the 70S ribosome. {ECO:0000255|HAMAP-Rule:MF_01367}.
CC   -!- SUBUNIT: Part of the 50S ribosomal subunit (PubMed:30126986). Forms a
CC       cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19
CC       interact and together make contacts with the 16S rRNA in bridges B5 and
CC       B8 (By similarity). {ECO:0000255|HAMAP-Rule:MF_01367,
CC       ECO:0000269|PubMed:30126986}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL14 family.
CC       {ECO:0000255|HAMAP-Rule:MF_01367}.
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DR   EMBL; X15664; CAA33701.1; -; Genomic_DNA.
DR   EMBL; L47971; AAB06809.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB11902.1; -; Genomic_DNA.
DR   PIR; S05992; R5BS4B.
DR   RefSeq; NP_388007.1; NC_000964.3.
DR   RefSeq; WP_003225805.1; NZ_JNCM01000029.1.
DR   PDB; 3J3V; EM; 13.30 A; K=1-122.
DR   PDB; 3J3W; EM; 10.70 A; K=1-122.
DR   PDB; 3J9W; EM; 3.90 A; BN=1-122.
DR   PDB; 5NJT; EM; 3.80 A; d=1-122.
DR   PDB; 6HA1; EM; 3.10 A; K=1-122.
DR   PDB; 6HA8; EM; 3.50 A; K=1-122.
DR   PDB; 6HTQ; EM; 4.50 A; K=1-122.
DR   PDB; 6PPF; EM; 3.40 A; K=1-122.
DR   PDB; 6PPK; EM; 4.40 A; K=1-122.
DR   PDB; 6PVK; EM; 3.40 A; K=1-122.
DR   PDB; 6TNN; EM; 3.07 A; d=1-122.
DR   PDB; 6TPQ; EM; 3.07 A; d=1-122.
DR   PDB; 7AQC; EM; 2.99 A; K=1-122.
DR   PDB; 7AQD; EM; 3.10 A; K=1-122.
DR   PDB; 7AS8; EM; 2.90 A; O=1-122.
DR   PDB; 7AS9; EM; 3.50 A; O=1-122.
DR   PDBsum; 3J3V; -.
DR   PDBsum; 3J3W; -.
DR   PDBsum; 3J9W; -.
DR   PDBsum; 5NJT; -.
DR   PDBsum; 6HA1; -.
DR   PDBsum; 6HA8; -.
DR   PDBsum; 6HTQ; -.
DR   PDBsum; 6PPF; -.
DR   PDBsum; 6PPK; -.
DR   PDBsum; 6PVK; -.
DR   PDBsum; 6TNN; -.
DR   PDBsum; 6TPQ; -.
DR   PDBsum; 7AQC; -.
DR   PDBsum; 7AQD; -.
DR   PDBsum; 7AS8; -.
DR   PDBsum; 7AS9; -.
DR   SMR; P12875; -.
DR   STRING; 224308.BSU01260; -.
DR   jPOST; P12875; -.
DR   PaxDb; P12875; -.
DR   PRIDE; P12875; -.
DR   EnsemblBacteria; CAB11902; CAB11902; BSU_01260.
DR   GeneID; 50135133; -.
DR   GeneID; 64301964; -.
DR   GeneID; 935939; -.
DR   KEGG; bsu:BSU01260; -.
DR   PATRIC; fig|224308.179.peg.129; -.
DR   eggNOG; COG0093; Bacteria.
DR   InParanoid; P12875; -.
DR   OMA; AKEVLCI; -.
DR   PhylomeDB; P12875; -.
DR   BioCyc; BSUB:BSU01260-MONOMER; -.
DR   PRO; PR:P12875; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0070180; F:large ribosomal subunit rRNA binding; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.40.150.20; -; 1.
DR   HAMAP; MF_01367; Ribosomal_L14; 1.
DR   InterPro; IPR036853; Ribosomal_L14_sf.
DR   InterPro; IPR000218; Ribosomal_L14P.
DR   InterPro; IPR005745; Ribosomal_L14P_bac-type.
DR   InterPro; IPR019972; Ribosomal_L14P_CS.
DR   PANTHER; PTHR11761; PTHR11761; 1.
DR   Pfam; PF00238; Ribosomal_L14; 1.
DR   SMART; SM01374; Ribosomal_L14; 1.
DR   SUPFAM; SSF50193; SSF50193; 1.
DR   TIGRFAMs; TIGR01067; rplN_bact; 1.
DR   PROSITE; PS00049; RIBOSOMAL_L14; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW   RNA-binding; rRNA-binding.
FT   CHAIN           1..122
FT                   /note="50S ribosomal protein L14"
FT                   /id="PRO_0000128530"
FT   STRAND          7..10
FT                   /evidence="ECO:0007829|PDB:7AS8"
FT   STRAND          12..29
FT                   /evidence="ECO:0007829|PDB:7AS8"
FT   STRAND          38..46
FT                   /evidence="ECO:0007829|PDB:7AS8"
FT   STRAND          48..52
FT                   /evidence="ECO:0007829|PDB:7AS8"
FT   STRAND          57..64
FT                   /evidence="ECO:0007829|PDB:7AS8"
FT   STRAND          72..74
FT                   /evidence="ECO:0007829|PDB:6PPF"
FT   STRAND          76..81
FT                   /evidence="ECO:0007829|PDB:7AS8"
FT   STRAND          83..96
FT                   /evidence="ECO:0007829|PDB:7AS8"
FT   STRAND          100..102
FT                   /evidence="ECO:0007829|PDB:7AS9"
FT   HELIX           104..106
FT                   /evidence="ECO:0007829|PDB:7AS8"
FT   TURN            107..110
FT                   /evidence="ECO:0007829|PDB:7AS8"
FT   HELIX           112..117
FT                   /evidence="ECO:0007829|PDB:7AS8"
FT   STRAND          119..121
FT                   /evidence="ECO:0007829|PDB:7AS9"
SQ   SEQUENCE   122 AA;  13154 MW;  1C54AECFD7F87E72 CRC64;
     MIQQETRLKV ADNSGAREVL TIKVLGGSGR KTANIGDVIV CTVKQATPGG VVKKGEVVKA
     VIVRTKSGAR RSDGSYISFD ENACVIIRDD KSPRGTRIFG PVARELRENN FMKIVSLAPE
     VI
//
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