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Database: UniProt
Entry: P42316
LinkDB: P42316
Original site: P42316 
ID   SCOB_BACSU              Reviewed;         216 AA.
AC   P42316;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   02-JUN-2021, entry version 125.
DE   RecName: Full=Probable succinyl-CoA:3-ketoacid coenzyme A transferase subunit B;
DE            EC=2.8.3.5;
DE   AltName: Full=OXCT B;
DE   AltName: Full=Succinyl-CoA:3-oxoacid CoA-transferase;
GN   Name=scoB; Synonyms=yxjE; OrderedLocusNames=BSU38980; ORFNames=N15L;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168 / BGSC1A1;
RX   PubMed=8969509; DOI=10.1099/13500872-142-11-3113;
RA   Yoshida K., Shindo K., Sano H., Seki S., Fujimura M., Yanai N., Miwa Y.,
RA   Fujita Y.;
RT   "Sequencing of a 65 kb region of the Bacillus subtilis genome containing
RT   the lic and cel loci, and creation of a 177 kb contig covering the gnt-
RT   sacXY region.";
RL   Microbiology 142:3113-3123(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate;
CC         Xref=Rhea:RHEA:24564, ChEBI:CHEBI:30031, ChEBI:CHEBI:35973,
CC         ChEBI:CHEBI:57292, ChEBI:CHEBI:90726; EC=2.8.3.5;
CC         Evidence={ECO:0000255|PROSITE-ProRule:PRU10034};
CC   -!- SUBUNIT: Heterodimer of a subunit A and a subunit B. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the 3-oxoacid CoA-transferase subunit B family.
CC       {ECO:0000305}.
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DR   EMBL; D83026; BAA11706.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB15924.1; -; Genomic_DNA.
DR   PIR; C70079; C70079.
DR   RefSeq; NP_391777.1; NC_000964.3.
DR   RefSeq; WP_003243049.1; NZ_JNCM01000034.1.
DR   PDB; 3CDK; X-ray; 2.59 A; B/D=1-216.
DR   PDBsum; 3CDK; -.
DR   SMR; P42316; -.
DR   STRING; 224308.BSU38980; -.
DR   PaxDb; P42316; -.
DR   PRIDE; P42316; -.
DR   DNASU; 937453; -.
DR   EnsemblBacteria; CAB15924; CAB15924; BSU_38980.
DR   GeneID; 937453; -.
DR   KEGG; bsu:BSU38980; -.
DR   PATRIC; fig|224308.179.peg.4218; -.
DR   eggNOG; COG2057; Bacteria.
DR   InParanoid; P42316; -.
DR   OMA; ANWRVGS; -.
DR   PhylomeDB; P42316; -.
DR   BioCyc; BSUB:BSU38980-MONOMER; -.
DR   EvolutionaryTrace; P42316; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0008260; F:3-oxoacid CoA-transferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008775; F:acetate CoA-transferase activity; IBA:GO_Central.
DR   GO; GO:0008410; F:CoA-transferase activity; IBA:GO_Central.
DR   InterPro; IPR012791; 3-oxoacid_CoA-transf_B.
DR   InterPro; IPR004165; CoA_trans_fam_I.
DR   InterPro; IPR004164; CoA_transf_AS.
DR   InterPro; IPR037171; NagB/RpiA_transferase-like.
DR   PANTHER; PTHR13707; PTHR13707; 1.
DR   Pfam; PF01144; CoA_trans; 1.
DR   SMART; SM00882; CoA_trans; 1.
DR   SUPFAM; SSF100950; SSF100950; 1.
DR   TIGRFAMs; TIGR02428; pcaJ_scoB_fam; 1.
DR   PROSITE; PS01274; COA_TRANSF_2; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Reference proteome; Transferase.
FT   CHAIN           1..216
FT                   /note="Probable succinyl-CoA:3-ketoacid coenzyme A
FT                   transferase subunit B"
FT                   /id="PRO_0000157920"
FT   ACT_SITE        47
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10034"
FT   HELIX           2..13
FT                   /evidence="ECO:0007829|PDB:3CDK"
FT   STRAND          21..24
FT                   /evidence="ECO:0007829|PDB:3CDK"
FT   HELIX           28..33
FT                   /evidence="ECO:0007829|PDB:3CDK"
FT   STRAND          43..46
FT                   /evidence="ECO:0007829|PDB:3CDK"
FT   TURN            47..49
FT                   /evidence="ECO:0007829|PDB:3CDK"
FT   STRAND          50..54
FT                   /evidence="ECO:0007829|PDB:3CDK"
FT   TURN            59..61
FT                   /evidence="ECO:0007829|PDB:3CDK"
FT   STRAND          71..73
FT                   /evidence="ECO:0007829|PDB:3CDK"
FT   STRAND          75..82
FT                   /evidence="ECO:0007829|PDB:3CDK"
FT   HELIX           85..93
FT                   /evidence="ECO:0007829|PDB:3CDK"
FT   STRAND          99..102
FT                   /evidence="ECO:0007829|PDB:3CDK"
FT   STRAND          105..108
FT                   /evidence="ECO:0007829|PDB:3CDK"
FT   HELIX           129..135
FT                   /evidence="ECO:0007829|PDB:3CDK"
FT   STRAND          136..142
FT                   /evidence="ECO:0007829|PDB:3CDK"
FT   STRAND          152..157
FT                   /evidence="ECO:0007829|PDB:3CDK"
FT   STRAND          163..166
FT                   /evidence="ECO:0007829|PDB:3CDK"
FT   STRAND          169..172
FT                   /evidence="ECO:0007829|PDB:3CDK"
FT   STRAND          174..181
FT                   /evidence="ECO:0007829|PDB:3CDK"
FT   STRAND          184..190
FT                   /evidence="ECO:0007829|PDB:3CDK"
FT   HELIX           196..201
FT                   /evidence="ECO:0007829|PDB:3CDK"
SQ   SEQUENCE   216 AA;  23331 MW;  2D0E402D7A62C0F5 CRC64;
     MKEARKRMVK RAVQEIKDGM NVNLGIGMPT LVANEIPDGV HVMLQSENGL LGIGPYPLEG
     TEDADLINAG KETITEVTGA SYFDSAESFA MIRGGHIDLA ILGGMEVSEQ GDLANWMIPG
     KMVKGMGGAM DLVNGAKRIV VIMEHVNKHG ESKVKKTCSL PLTGQKVVHR LITDLAVFDF
     VNGRMTLTEL QDGVTIEEVY EKTEADFAVS QSVLNS
//
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