ID Q0BZB1_HYPNA Unreviewed; 623 AA.
AC Q0BZB1;
DT 17-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 17-OCT-2006, sequence version 1.
DT 28-JAN-2026, entry version 130.
DE SubName: Full=Selenocysteine-specific translation elongation factor {ECO:0000313|EMBL:ABI76610.1};
GN Name=selB {ECO:0000313|EMBL:ABI76610.1};
GN OrderedLocusNames=HNE_2488 {ECO:0000313|EMBL:ABI76610.1};
OS Hyphomonas neptunium (strain ATCC 15444).
OC Bacteria; Pseudomonadati; Pseudomonadota; Alphaproteobacteria;
OC Hyphomonadales; Hyphomonadaceae; Hyphomonas.
OX NCBI_TaxID=228405 {ECO:0000313|EMBL:ABI76610.1, ECO:0000313|Proteomes:UP000001959};
RN [1] {ECO:0000313|EMBL:ABI76610.1, ECO:0000313|Proteomes:UP000001959}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15444 {ECO:0000313|EMBL:ABI76610.1,
RC ECO:0000313|Proteomes:UP000001959};
RX PubMed=16980487; DOI=10.1128/JB.00111-06;
RA Badger J.H., Hoover T.R., Brun Y.V., Weiner R.M., Laub M.T., Alexandre G.,
RA Mrazek J., Ren Q., Paulsen I.T., Nelson K.E., Khouri H.M., Radune D.,
RA Sosa J., Dodson R.J., Sullivan S.A., Rosovitz M.J., Madupu R.,
RA Brinkac L.M., Durkin A.S., Daugherty S.C., Kothari S.P., Giglio M.G.,
RA Zhou L., Haft D.H., Selengut J.D., Davidsen T.M., Yang Q., Zafar N.,
RA Ward N.L.;
RT "Comparative genomic evidence for a close relationship between the
RT dimorphic prosthecate bacteria Hyphomonas neptunium and Caulobacter
RT crescentus.";
RL J. Bacteriol. 188:6841-6850(2006).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; CP000158; ABI76610.1; -; Genomic_DNA.
DR RefSeq; WP_011647480.1; NC_008358.1.
DR AlphaFoldDB; Q0BZB1; -.
DR STRING; 228405.HNE_2488; -.
DR KEGG; hne:HNE_2488; -.
DR eggNOG; COG3276; Bacteria.
DR HOGENOM; CLU_023030_2_0_5; -.
DR Proteomes; UP000001959; Chromosome.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0004020; F:adenylylsulfate kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd15491; selB_III; 1.
DR Gene3D; 1.10.10.2770; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:ABI76610.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000001959}.
FT DOMAIN 1..171
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 623 AA; 64225 MW; 857C1CB5B42812F0 CRC64;
MKSCPVIVIG HVDHGKTSLV GALTGIETDR LPEEKARGLS ITSGFAYLKG GDANIDLVDA
PGHQNFIRAM VGGAAGARSA ALVVSAAEGV EAQTLEHIAV IETLGIHAGI VVLSKADLVA
PSERPGRKVA LQAALAGTAF RDAPLIFCSA VTGEGLEDIA AALRGLAALP AGAGPAGAFL
AIDRVFVAEG HGTVVTGTLL GRSLKPADEL LLAPSGEIVT IRRIEVRGET VSMAQPGERT
ALNLRGVAAS KIKPGDVVHA ADAGAASLNL DAAISVSARA GRPVRHMEEI RVLYGTGNGV
ATLRLLGRKE VSPGETGFAQ LRFTAPAAAF AGQRAVLRSL SPSQTLGGAI ILDPAATPLT
ASKALRLATL EAAYRGDTLA LAAALAAEQG GVARLGDVCR LARAPEASVR ASLGEAFTQI
ADGFVSPAAV VAEARDAYLA RLCAYHAEHR LRPQAPRSEI LAGHVSLLLN LHVEESLAAA
GVIRLSGGGV ALAIHDAAAN LTPDQTARMH GLARQLQADG LTPSGTAALI RSPEDAELLE
LLVERGEVIR LSNVSLKQTI WLHAEAVSSA IQMLRTGFPG ETAFTTGEAR EALKTSRKHI
VPLLEYLDAA GITQRQGDTR CMV
//
