ID Q2GSG6_CHAGB Unreviewed; 1365 AA.
AC Q2GSG6;
DT 21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2006, sequence version 1.
DT 18-JUN-2025, entry version 84.
DE RecName: Full=DBF4-type domain-containing protein {ECO:0000259|PROSITE:PS51265};
GN ORFNames=CHGG_09088 {ECO:0000313|EMBL:EAQ85074.1};
OS Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 /
OS NRRL 1970) (Soil fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Chaetomiaceae; Chaetomium.
OX NCBI_TaxID=306901 {ECO:0000313|EMBL:EAQ85074.1, ECO:0000313|Proteomes:UP000001056};
RN [1] {ECO:0000313|Proteomes:UP000001056}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970
RC {ECO:0000313|Proteomes:UP000001056};
RX PubMed=25720678; DOI=10.1128/genomeA.00021-15;
RA Cuomo C.A., Untereiner W.A., Ma L.-J., Grabherr M., Birren B.W.;
RT "Draft genome sequence of the cellulolytic fungus Chaetomium globosum.";
RL Genome Announc. 3:E0002115-E0002115(2015).
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DR EMBL; CH408034; EAQ85074.1; -; Genomic_DNA.
DR RefSeq; XP_001227015.1; XM_001227014.1.
DR STRING; 306901.Q2GSG6; -.
DR GeneID; 4395595; -.
DR VEuPathDB; FungiDB:CHGG_09088; -.
DR eggNOG; KOG4139; Eukaryota.
DR HOGENOM; CLU_256712_0_0_1; -.
DR InParanoid; Q2GSG6; -.
DR OrthoDB; 21380at2759; -.
DR Proteomes; UP000001056; Unassembled WGS sequence.
DR GO; GO:0031431; C:Dbf4-dependent protein kinase complex; IEA:TreeGrafter.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR GO; GO:0043539; F:protein serine/threonine kinase activator activity; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0010571; P:positive regulation of nuclear cell cycle DNA replication; IEA:TreeGrafter.
DR GO; GO:1901987; P:regulation of cell cycle phase transition; IEA:TreeGrafter.
DR FunFam; 6.10.250.3410:FF:000001; Protein DBF4 homolog A; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 6.10.250.3410; DBF zinc finger; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR055116; DBF4_BRCT.
DR InterPro; IPR000683; Gfo/Idh/MocA-like_OxRdtase_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR013939; Regulatory_Dfp1/Him1.
DR InterPro; IPR051590; Replication_Regulatory_Kinase.
DR InterPro; IPR006572; Znf_DBF.
DR InterPro; IPR038545; Znf_DBF_sf.
DR PANTHER; PTHR15375; ACTIVATOR OF S-PHASE KINASE-RELATED; 1.
DR PANTHER; PTHR15375:SF26; PROTEIN CHIFFON; 1.
DR Pfam; PF22437; DBF4_BRCT; 1.
DR Pfam; PF08630; Dfp1_Him1_M; 1.
DR Pfam; PF01408; GFO_IDH_MocA; 1.
DR Pfam; PF07535; zf-DBF; 1.
DR SMART; SM00586; ZnF_DBF; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51265; ZF_DBF4; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001056};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00600}.
FT DOMAIN 572..621
FT /note="DBF4-type"
FT /evidence="ECO:0000259|PROSITE:PS51265"
FT REGION 162..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 544..569
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 941..965
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1086..1146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1287..1323
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 166..188
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 544..555
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1091..1107
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1291..1303
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1365 AA; 147461 MW; BC0087EB44007051 CRC64;
MSTKRIPLSA SNPNVANSPM RALAGINGLK KGRLHADTVR EEPYGQPPPA KRQMIERGVA
SPSRPKTRTI VHRAAGAATR TTASTATTQR ASVASLIPAT EEELANLRTW HNQIRSRFPK
MVFYFEGIIE DELRAKLAKK IGRLGAHEEK FFSINITHVV TNRPIPPEKT KGEHEGETDP
HGDNEQPKTI DPSLLNRPAD PTRRKLTYDT APVSRKPSVL NQDDPLGRPK TRSTDVLDRA
RDMGKKIWSL EKLTKILELA LYPNRYINTR GLGTMQSTSK AADGERNLAR LLEHEREHGP
TDRDLTVSSN DLVKFTGPYI YVYDLEEKTK PIMIKEYRKA ADPKDQEWPQ FRVTSQGRCP
FVLDESHDHP EKEVRTRTRA AKVAGEAAEP AAPKHKASEI LLKNTAGKRT LAEMEDGHNR
GTAGTRLTES FDRSKIANPP SLEFRSQNAF ISHAKAGRFL AGEPVASGLQ PSNVTSAIRS
QMISSTTGGV LGAKAGTSKE IHGLQRKVVI SQDPSSRRMV ELSHDNGTFV RSTSFSQTIQ
RKLDPVHEEG TSRQREKLRR TASVPVPQAR KRDLKPGYCE NCQDKFADFE EHILSRKHRK
FAEDDNNWVD LDNLLSQLAL YPMVSKSNSR AGRRRFASTR RMYRFWIKLP EPAEKDANPL
LTFGIMGAER AAYTLLIKPA ERRSDVIVRA IACTYPPAAE KFRSRNDIPI AYTSYDRILQ
DQEINAVLIC LPLDLRYEWA YKALASGRHV LLDSPGTGNL RDMFLLYCDY KELYSTFLAP
PVLLKASPYL FHPSWQEFES KLDRPKLVKV TVNILLPTTI TEDKEARFRY EHAGGCGMGV
MHAMSLLRDF PRGAIGEVRG RSRMSMRGGY PHGSTAAGVT IDALHRADHP NPPPGQRVIE
ERTVTLRYSR GGPSHHVIRV RTDREHKNAR NGRTLQRSIT TQTHKAYEPR RNPKQLPPVP
QPKADWTAPM YQLDAFVRRA RNPLPPGIEP LHPPPWVEAD AACGLGATLG GGVELGSGVA
EGAGSEAEFG AGGGFGSGAG AGFGGGAGPG SVAERVSRTE LVPAATGGFG PEAEFGSGAE
FGSGAAARFG SGEHRVPDAA ADPEAKSGSR AKFSSGAGAG WFGSGAERIP DAAADPEAKS
GSEAEFGSGA ELVSGAELVS RAELASGTEL VPAAGSGCGA EFGTGAEFCA GTKLVPGTEF
VPAAAADSGP KTEFDSGTEF HPGAKLISGA ELVPGTELVP TGGSDPKAFF GSGAGFALNT
NAANTAGAAG AAGNGGRAFP GRKLVTGTEY GSGTVSDSGT DSGPRARPYS EATAGSGARP
DSVAGALSRA WDDLAPGVEL DKLAKPTPCN REIRQFVVIK GVEKH
//
