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Database: UniProt
Entry: Q6CJK0
LinkDB: Q6CJK0
Original site: Q6CJK0 
ID   Q6CJK0_KLULA            Unreviewed;       151 AA.
AC   Q6CJK0;
DT   16-AUG-2004, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2008, sequence version 2.
DT   07-APR-2021, entry version 105.
DE   SubName: Full=KLLA0F18040p {ECO:0000313|EMBL:CAG98597.2};
GN   ORFNames=KLLA0_F18040g {ECO:0000313|EMBL:CAG98597.2};
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590 {ECO:0000313|Proteomes:UP000000598};
RN   [1] {ECO:0000313|EMBL:CAG98597.2, ECO:0000313|Proteomes:UP000000598}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 /
RC   WM37 {ECO:0000313|Proteomes:UP000000598};
RX   PubMed=15229592; DOI=10.1038/nature02579;
RG   Genolevures;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.F., Straub M.L.,
RA   Suleau A., Swennene D., Tekaia F., Wesolowski-Louvel M., Westhof E.,
RA   Wirth B., Zeniou-Meyer M., Zivanovic I., Bolotin-Fukuhara M., Thierry A.,
RA   Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA   Wincker P., Souciet J.L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
RN   [2] {ECO:0007829|PDB:3J80, ECO:0007829|PDB:3J81}
RP   STRUCTURE BY ELECTRON MICROSCOPY (3.75 ANGSTROMS).
RX   PubMed=25417110; DOI=10.1016/j.cell.2014.10.001;
RA   Hussain T., Llacer J.L., Fernandez I.S., Munoz A., Martin-Marcos P.,
RA   Savva C.G., Lorsch J.R., Hinnebusch A.G., Ramakrishnan V.;
RT   "Structural changes enable start codon recognition by the eukaryotic
RT   translation initiation complex.";
RL   Cell 159:597-607(2014).
RN   [3] {ECO:0007829|PDB:3JAM, ECO:0007829|PDB:3JAP}
RP   STRUCTURE BY ELECTRON MICROSCOPY (3.46 ANGSTROMS).
RX   PubMed=26212456; DOI=10.1016/j.molcel.2015.06.033;
RA   Llacer J.L., Hussain T., Marler L., Aitken C.E., Thakur A., Lorsch J.R.,
RA   Hinnebusch A.G., Ramakrishnan V.;
RT   "Conformational differences between open and closed states of the
RT   eukaryotic translation initiation complex.";
RL   Mol. Cell 59:399-412(2015).
RN   [4] {ECO:0007829|PDB:5IT7, ECO:0007829|PDB:5IT9}
RP   STRUCTURE BY ELECTRON MICROSCOPY (3.60 ANGSTROMS) OF 2-151.
RX   PubMed=27159451; DOI=10.7554/eLife.13567;
RA   Murray J., Savva C.G., Shin B.S., Dever T.E., Ramakrishnan V.,
RA   Fernandez I.S.;
RT   "Structural characterization of ribosome recruitment and translocation by
RT   type IV IRES.";
RL   Elife 5:0-0(2016).
RN   [5] {ECO:0007829|PDB:6FYX, ECO:0007829|PDB:6FYY}
RP   STRUCTURE BY ELECTRON MICROSCOPY (3.05 ANGSTROMS).
RX   PubMed=30475211; DOI=10.7554/eLife.39273;
RA   Llacer J.L., Hussain T., Saini A.K., Nanda J.S., Kaur S., Gordiyenko Y.,
RA   Kumar R., Hinnebusch A.G., Lorsch J.R., Ramakrishnan V.;
RT   "Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal
RT   subunit to promote start-codon recognition.";
RL   Elife 7:0-0(2018).
RN   [6] {ECO:0007829|PDB:6GSM, ECO:0007829|PDB:6GSN}
RP   STRUCTURE BY ELECTRON MICROSCOPY (5.75 ANGSTROMS) OF 2-151.
RA   Llacer J.L., Hussain T., Gordiyenko Y., Ramakrishnan V.;
RT   "Towards a model of eIF3 on the 40S subunit interface in eukaryotic
RT   translation initiation.";
RL   Submitted (JUN-2018) to the PDB data bank.
RN   [7] {ECO:0007829|PDB:6UZ7}
RP   STRUCTURE BY ELECTRON MICROSCOPY (3.60 ANGSTROMS).
RX   PubMed=31900355; DOI=10.1073/pnas.1916436117;
RA   Huang B.Y., Fernandez I.S.;
RT   "Long-range interdomain communications in eIF5B regulate GTP hydrolysis and
RT   translation initiation.";
RL   Proc. Natl. Acad. Sci. U.S.A. 117:1429-1437(2020).
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uS15 family.
CC       {ECO:0000256|ARBA:ARBA00008434, ECO:0000256|RuleBase:RU003919}.
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DR   EMBL; CR382126; CAG98597.2; -; Genomic_DNA.
DR   RefSeq; XP_455889.2; XM_455889.2.
DR   PDB; 3J80; EM; 3.75 A; N=1-151.
DR   PDB; 3J81; EM; 4.00 A; N=1-151.
DR   PDB; 3JAM; EM; 3.46 A; N=1-151.
DR   PDB; 3JAP; EM; 4.90 A; N=1-151.
DR   PDB; 3JAQ; EM; 6.00 A; N=1-151.
DR   PDB; 5IT7; EM; 3.60 A; N=2-151.
DR   PDB; 5IT9; EM; 3.80 A; N=2-151.
DR   PDB; 6FYX; EM; 3.05 A; N=1-151.
DR   PDB; 6FYY; EM; 3.05 A; N=1-151.
DR   PDB; 6GSM; EM; 5.15 A; N=2-151.
DR   PDB; 6GSN; EM; 5.75 A; N=2-151.
DR   PDB; 6UZ7; EM; 3.60 A; N=1-151.
DR   PDBsum; 3J80; -.
DR   PDBsum; 3J81; -.
DR   PDBsum; 3JAM; -.
DR   PDBsum; 3JAP; -.
DR   PDBsum; 3JAQ; -.
DR   PDBsum; 5IT7; -.
DR   PDBsum; 5IT9; -.
DR   PDBsum; 6FYX; -.
DR   PDBsum; 6FYY; -.
DR   PDBsum; 6GSM; -.
DR   PDBsum; 6GSN; -.
DR   PDBsum; 6UZ7; -.
DR   SMR; Q6CJK0; -.
DR   STRING; 28985.XP_455889.2; -.
DR   EnsemblFungi; CAG98597; CAG98597; KLLA0_F18040g.
DR   GeneID; 2895585; -.
DR   KEGG; kla:KLLA0_F18040g; -.
DR   eggNOG; KOG0400; Eukaryota.
DR   HOGENOM; CLU_090139_1_0_1; -.
DR   InParanoid; Q6CJK0; -.
DR   OMA; WHLVKKA; -.
DR   Proteomes; UP000000598; Chromosome F.
DR   GO; GO:0022627; C:cytosolic small ribosomal subunit; IEA:EnsemblFungi.
DR   GO; GO:0070181; F:small ribosomal subunit rRNA binding; IEA:EnsemblFungi.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:EnsemblFungi.
DR   GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   CDD; cd00353; Ribosomal_S15p_S13e; 1.
DR   HAMAP; MF_01343_A; Ribosomal_S15_A; 1.
DR   InterPro; IPR012606; Ribosomal_S13/S15_N.
DR   InterPro; IPR000589; Ribosomal_S15.
DR   InterPro; IPR023029; Ribosomal_S15P.
DR   InterPro; IPR009068; S15_NS1_RNA-bd.
DR   PANTHER; PTHR11885; PTHR11885; 1.
DR   Pfam; PF08069; Ribosomal_S13_N; 1.
DR   Pfam; PF00312; Ribosomal_S15; 1.
DR   SMART; SM01386; Ribosomal_S13_N; 1.
DR   SMART; SM01387; Ribosomal_S15; 1.
DR   SUPFAM; SSF47060; SSF47060; 1.
DR   PROSITE; PS00362; RIBOSOMAL_S15; 1.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0007829|PDB:3J80, ECO:0007829|PDB:3J81};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000598};
KW   Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW   ECO:0000256|RuleBase:RU003919};
KW   Ribosomal protein {ECO:0000256|ARBA:ARBA00022980,
KW   ECO:0000256|RuleBase:RU003919}.
FT   DOMAIN          1..60
FT                   /note="Ribosomal_S13_N"
FT                   /evidence="ECO:0000259|SMART:SM01386"
SQ   SEQUENCE   151 AA;  16958 MW;  E6F60C91B2D279F2 CRC64;
     MGRMHSKGKG MSSSAIPYSR NAPAWFKGSS DGVVEQIIKY ARKGLTPSQI GVLLRDAHGV
     TQAKVITGNK ILRILKSNGL APEIPEDLYF LIKKAVSVRK HLERNRKDKD AKFRLILIES
     RIHRLARYYR TVSVLPPNWK YESATASALV N
//
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