ID Q6CKD0_KLULA Unreviewed; 625 AA.
AC Q6CKD0;
DT 16-AUG-2004, integrated into UniProtKB/TrEMBL.
DT 16-AUG-2004, sequence version 1.
DT 28-JAN-2026, entry version 101.
DE SubName: Full=KLLA0F11660p {ECO:0000313|EMBL:CAG98317.1};
GN ORFNames=KLLA0_F11660g {ECO:0000313|EMBL:CAG98317.1};
OS Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX NCBI_TaxID=284590 {ECO:0000313|EMBL:CAG98317.1, ECO:0000313|Proteomes:UP000000598};
RN [1] {ECO:0000313|EMBL:CAG98317.1, ECO:0000313|Proteomes:UP000000598}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 /
RC WM37 {ECO:0000313|Proteomes:UP000000598};
RX PubMed=15229592; DOI=10.1038/nature02579;
RG Genolevures;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.F., Straub M.L.,
RA Suleau A., Swennene D., Tekaia F., Wesolowski-Louvel M., Westhof E.,
RA Wirth B., Zeniou-Meyer M., Zivanovic I., Bolotin-Fukuhara M., Thierry A.,
RA Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA Wincker P., Souciet J.L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
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DR EMBL; CR382126; CAG98317.1; -; Genomic_DNA.
DR AlphaFoldDB; Q6CKD0; -.
DR FunCoup; Q6CKD0; 215.
DR STRING; 284590.Q6CKD0; -.
DR PaxDb; 284590-Q6CKD0; -.
DR KEGG; kla:KLLA0_F11660g; -.
DR eggNOG; KOG4139; Eukaryota.
DR HOGENOM; CLU_023948_0_0_1; -.
DR InParanoid; Q6CKD0; -.
DR OMA; GMKIWAI; -.
DR Proteomes; UP000000598; Chromosome F.
DR GO; GO:0031431; C:Dbf4-dependent protein kinase complex; IEA:TreeGrafter.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0043539; F:protein serine/threonine kinase activator activity; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0010571; P:positive regulation of nuclear cell cycle DNA replication; IEA:TreeGrafter.
DR GO; GO:1901987; P:regulation of cell cycle phase transition; IEA:TreeGrafter.
DR FunFam; 6.10.250.3410:FF:000001; Protein DBF4 homolog A; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 6.10.250.3410; DBF zinc finger; 1.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR055116; DBF4_BRCT.
DR InterPro; IPR013939; Regulatory_Dfp1/Him1.
DR InterPro; IPR051590; Replication_Regulatory_Kinase.
DR InterPro; IPR006572; Znf_DBF.
DR InterPro; IPR038545; Znf_DBF_sf.
DR PANTHER; PTHR15375; ACTIVATOR OF S-PHASE KINASE-RELATED; 1.
DR PANTHER; PTHR15375:SF26; PROTEIN CHIFFON; 1.
DR Pfam; PF22437; DBF4_BRCT; 1.
DR Pfam; PF08630; Dfp1_Him1_M; 1.
DR Pfam; PF07535; zf-DBF; 1.
DR SMART; SM00586; ZnF_DBF; 1.
DR PROSITE; PS51265; ZF_DBF4; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000000598};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00600}.
FT DOMAIN 570..619
FT /note="DBF4-type"
FT /evidence="ECO:0000259|PROSITE:PS51265"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 625 AA; 69340 MW; 592F6FE4EC51E51D CRC64;
MAKNTRSPLK ESNPNTMGNH IHNPKKRSLD LLELEQSNRQ KQRTLRTIEG AIAHAPNALL
KTVQGGTTNT FNINATGVKS GAHVGVNDPV AASVSASVSA GGSMMRNSNE HGIIGGNGSP
AIANAKAQTQ RLSNKELIDW QNNWKKIMKR DTFIYFDCPE VANDNRKDVL RRAFSTLGAK
VKQFFDHEVT IVITSRKITN YSQLPDTDIL QRAHKRGYMK IWTLEKAARF LTNMDVDLKE
MERDSISGKS IPASNLLNLL ESEKLFGSNE RDPKTKRDDL HYFKHPHVYL YDLAQINAPL
ITLEWKAQDI NNKKKHIYPT IKPGSFGRCP FQGDETADEL QPRRIIKRYK RDKANESYAM
KLRLLYQTSA EPATLSSSET SDYEGDDAIL SFPDPSSKEP IILPYQNVYN NSGAQYNKLV
NSMSRFKQPK LPRGDTFDDD ELPYGNGTGT IGGTGSYKNK FQQEIRASGV QSVDANSNGN
ATVGNGLEPA KASNLNKDLL SLKKMVIERK SLLSASTTST SANTVGSVNS GKLHNHNIAA
SGVNQTNPTS TVSKQQLPAL TPQRLHQPIG RQTAGYCENC KVKYDSLEAH VSTERHIAFA
SKDEHFQGVD SMIQCVQQFR DINSA
//
