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Database: UniProt
Entry: Q772X2
LinkDB: Q772X2
Original site: Q772X2 
ID   Q772X2_9ADEN            Unreviewed;       325 AA.
AC   Q772X2;
DT   29-MAR-2005, integrated into UniProtKB/TrEMBL.
DT   29-MAR-2005, sequence version 1.
DT   07-APR-2021, entry version 64.
DE   SubName: Full=Fiber 36.1 kDa protein {ECO:0000313|EMBL:AAN62521.1};
OS   Human adenovirus 11.
OC   Viruses; Varidnaviria; Bamfordvirae; Preplasmiviricota; Tectiliviricetes;
OC   Rowavirales; Adenoviridae; Mastadenovirus; Human mastadenovirus B.
OX   NCBI_TaxID=10541 {ECO:0000313|EMBL:AAN62521.1, ECO:0000313|Proteomes:UP000152074};
RN   [1] {ECO:0000313|EMBL:AAN62521.1, ECO:0000313|Proteomes:UP000152074}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ad11p Slobitski {ECO:0000313|EMBL:AAN62521.1};
RX   PubMed=12726735; DOI=10.1016/S0042-6822(02)00085-5;
RA   Stone D., Furthmann A., Sandig V., Lieber A.;
RT   "The complete nucleotide sequence, genome organization, and origin of human
RT   adenovirus type 11.";
RL   Virology 309:152-165(2003).
RN   [2] {ECO:0000313|EMBL:AAN62521.1, ECO:0000313|Proteomes:UP000152074}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ad11p Slobitski {ECO:0000313|EMBL:AAN62521.1};
RX   PubMed=15795294; DOI=10.1128/JVI.79.8.5090-5104.2005;
RA   Stone D., Ni S., Li Z.Y., Gaggar A., DiPaolo N., Feng Q., Sandig V.,
RA   Lieber A.;
RT   "Development and assessment of human adenovirus type 11 as a gene transfer
RT   vector.";
RL   J. Virol. 79:5090-5104(2005).
RN   [3] {ECO:0007829|PDB:3O8E}
RP   X-RAY CRYSTALLOGRAPHY (2.84 ANGSTROMS) OF 117-325.
RX   PubMed=20941397; DOI=10.1371/journal.ppat.1001122;
RA   Persson B.D., Schmitz N.B., Santiago C., Zocher G., Larvie M., Scheu U.,
RA   Casasnovas J.M., Stehle T.;
RT   "Structure of the extracellular portion of CD46 provides insights into its
RT   interactions with complement proteins and pathogens.";
RL   PLoS Pathog. 6:e1001122-e1001122(2010).
CC   -!- SUBCELLULAR LOCATION: Host nucleus {ECO:0000256|ARBA:ARBA00004147}.
CC       Nucleus {ECO:0000256|ARBA:ARBA00004123}. Virion
CC       {ECO:0000256|ARBA:ARBA00004328}.
CC   -!- SIMILARITY: Belongs to the adenoviridae fiber family.
CC       {ECO:0000256|ARBA:ARBA00006685}.
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DR   EMBL; AY163756; AAN62521.1; -; Genomic_DNA.
DR   PDB; 3O8E; X-ray; 2.84 A; A/C=117-325.
DR   PDBsum; 3O8E; -.
DR   SMR; Q772X2; -.
DR   EvolutionaryTrace; Q772X2; -.
DR   Proteomes; UP000152074; Genome.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0098671; P:adhesion receptor-mediated virion attachment to host cell; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.90.10; -; 1.
DR   InterPro; IPR000931; Adeno_fibre.
DR   InterPro; IPR000978; Adeno_fibre_knob.
DR   InterPro; IPR000939; Adenobir_fibre_prot_rpt/shaft.
DR   InterPro; IPR008982; Adenovirus_pIV-like_att.
DR   InterPro; IPR009013; Attachment_protein_shaft_sf.
DR   Pfam; PF00541; Adeno_knob; 1.
DR   Pfam; PF00608; Adeno_shaft; 2.
DR   PRINTS; PR00307; ADENOVSFIBRE.
DR   SUPFAM; SSF49835; SSF49835; 1.
DR   SUPFAM; SSF51225; SSF51225; 1.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0007829|PDB:3O8E};
KW   Capsid protein {ECO:0000256|ARBA:ARBA00022561};
KW   Host nucleus {ECO:0000256|ARBA:ARBA00022562};
KW   Host-virus interaction {ECO:0000256|ARBA:ARBA00022581};
KW   Late protein {ECO:0000256|ARBA:ARBA00022921};
KW   Viral attachment to host adhesion receptor {ECO:0000256|ARBA:ARBA00023165};
KW   Viral attachment to host cell {ECO:0000256|ARBA:ARBA00022804};
KW   Virion {ECO:0000256|ARBA:ARBA00022844};
KW   Virus entry into host cell {ECO:0000256|ARBA:ARBA00023296}.
FT   DOMAIN          134..320
FT                   /note="Adeno_knob"
FT                   /evidence="ECO:0000259|Pfam:PF00541"
SQ   SEQUENCE   325 AA;  35538 MW;  3B3ACCA4CBDB3EFD CRC64;
     MTKRVRLSDS FNPVYPYEDE STSQHPFINP GFISPNGFTQ SPNGVLTLKC LTPLTTTGGS
     LQLKVGGGLT VDDTNGFLKE NISATTPLVK TGHSIGLPLG AGLGTNENKL CIKLGQGLTF
     NSNNICIDDN INTLWTGVNP TEANCQIMNS SESNDCKLIL TLVKTGALVT AFVYVIGVSN
     NFNMLTTHRN INFTAELFFD STGNLLTRLS SLKTPLNHKS GQNMATGAIT NAKGFMPSTT
     AYPFNDNSRE KENYIYGTCY YTASDRTAFP IDISVMLNRR AINDETSYCI RITWSWNTGD
     APEVQTSATT LVTSPFTFYY IREDD
//
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