ID   Q8IWM3_HUMAN            Unreviewed;        55 AA.
AC   Q8IWM3;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   SubName: Full=D-amino acid oxidase activator {ECO:0000313|Ensembl:ENSP00000471091};
DE   SubName: Full=Putative schizophrenia protein variant 2 {ECO:0000313|EMBL:AAO12728.1};
GN   Name=DAOA {ECO:0000313|Ensembl:ENSP00000471091};
GN   Synonyms=G72 {ECO:0000313|EMBL:AAO12728.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:AAO12728.1};
RN   [1] {ECO:0000313|EMBL:AAO12728.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Testis {ECO:0000313|EMBL:AAO12728.1};
RX   PubMed=12647258; DOI=10.1086/374822;
RA   Hattori E., Liu C., Badner J.A., Bonner T.I., Christian S.L.,
RA   Maheshwari M., Detera-Wadleigh S.D., Gibbs R.A., Gershon E.S.;
RT   "Polymorphisms at the G72/G30 gene locus, on 13q33, are associated with
RT   bipolar disorder in two independent pedigree series.";
RL   Am. J. Hum. Genet. 72:1131-1140(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000471091, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057823; DOI=10.1038/nature02379;
RA   Dunham A., Matthews L.H., Burton J., Ashurst J.L., Howe K.L.,
RA   Ashcroft K.J., Beare D.M., Burford D.C., Hunt S.E., Griffiths-Jones S.,
RA   Jones M.C., Keenan S.J., Oliver K., Scott C.E., Ainscough R., Almeida J.P.,
RA   Ambrose K.D., Andrews D.T., Ashwell R.I.S., Babbage A.K., Bagguley C.L.,
RA   Bailey J., Bannerjee R., Barlow K.F., Bates K., Beasley H., Bird C.P.,
RA   Bray-Allen S., Brown A.J., Brown J.Y., Burrill W., Carder C., Carter N.P.,
RA   Chapman J.C., Clamp M.E., Clark S.Y., Clarke G., Clee C.M., Clegg S.C.,
RA   Cobley V., Collins J.E., Corby N., Coville G.J., Deloukas P., Dhami P.,
RA   Dunham I., Dunn M., Earthrowl M.E., Ellington A.G., Faulkner L.,
RA   Frankish A.G., Frankland J., French L., Garner P., Garnett J.,
RA   Gilbert J.G.R., Gilson C.J., Ghori J., Grafham D.V., Gribble S.M.,
RA   Griffiths C., Hall R.E., Hammond S., Harley J.L., Hart E.A., Heath P.D.,
RA   Howden P.J., Huckle E.J., Hunt P.J., Hunt A.R., Johnson C., Johnson D.,
RA   Kay M., Kimberley A.M., King A., Laird G.K., Langford C.J., Lawlor S.,
RA   Leongamornlert D.A., Lloyd D.M., Lloyd C., Loveland J.E., Lovell J.,
RA   Martin S., Mashreghi-Mohammadi M., McLaren S.J., McMurray A., Milne S.,
RA   Moore M.J.F., Nickerson T., Palmer S.A., Pearce A.V., Peck A.I., Pelan S.,
RA   Phillimore B., Porter K.M., Rice C.M., Searle S., Sehra H.K., Shownkeen R.,
RA   Skuce C.D., Smith M., Steward C.A., Sycamore N., Tester J., Thomas D.W.,
RA   Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P.,
RA   Whitehead S.L., Willey D.L., Wilming L., Wray P.W., Wright M.W., Young L.,
RA   Coulson A., Durbin R., Hubbard T., Sulston J.E., Beck S., Bentley D.R.,
RA   Rogers J., Ross M.T.;
RT   "The DNA sequence and analysis of human chromosome 13.";
RL   Nature 428:522-528(2004).
RN   [3] {ECO:0000313|Ensembl:ENSP00000471091}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2013) to UniProtKB.
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DR   EMBL; AL359751; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AY170470; AAO12728.1; -; mRNA.
DR   PRIDE; Q8IWM3; -.
DR   Ensembl; ENST00000488534.5; ENSP00000471091.1; ENSG00000182346.22.
DR   UCSC; uc058ydg.1; human.
DR   HGNC; HGNC:21191; DAOA.
DR   VEuPathDB; HostDB:ENSG00000182346; -.
DR   GeneTree; ENSGT00410000028557; -.
DR   HOGENOM; CLU_3031694_0_0_1; -.
DR   Proteomes; UP000005640; Chromosome 13.
DR   Bgee; ENSG00000182346; Expressed in ganglionic eminence.
DR   ExpressionAtlas; Q8IWM3; baseline and differential.
DR   GO; GO:1900758; P:negative regulation of D-amino-acid oxidase activity; IEA:InterPro.
DR   InterPro; IPR027929; DAOA.
DR   Pfam; PF15199; DAOA; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640}.
SQ   SEQUENCE   55 AA;  6394 MW;  2D88FB407D2C4808 CRC64;
     MAQRHLQRSL CPWVSYLPQP YAEHSKVILN GNLHCHFKRI SQIFAGHFME GDTEA
//