ID Q8RDT5_FUSNN Unreviewed; 222 AA.
AC Q8RDT5;
DT 01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2002, sequence version 1.
DT 08-OCT-2025, entry version 106.
DE SubName: Full=Fuculose phosphate aldolase {ECO:0000313|EMBL:AAL95610.1, ECO:0000313|EMBL:AVQ15712.1};
DE EC=4.1.2.17 {ECO:0000313|EMBL:AAL95610.1, ECO:0000313|EMBL:AVQ15712.1};
GN OrderedLocusNames=FN1417 {ECO:0000313|EMBL:AAL95610.1};
GN ORFNames=C7Y58_10080 {ECO:0000313|EMBL:AVQ15712.1};
OS Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 /
OS BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355).
OC Bacteria; Fusobacteriati; Fusobacteriota; Fusobacteriia; Fusobacteriales;
OC Fusobacteriaceae; Fusobacterium.
OX NCBI_TaxID=190304 {ECO:0000313|EMBL:AAL95610.1};
RN [1] {ECO:0000313|EMBL:AAL95610.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25586 {ECO:0000313|EMBL:AAL95610.1};
RX PubMed=11889109; DOI=10.1128/JB.184.7.2005-2018.2002;
RA Kapatral V., Anderson I., Ivanova N., Reznik G., Los T., Lykidis A.,
RA Bhattacharyya A., Bartman A., Gardner W., Grechkin G., Zhu L., Vasieva O.,
RA Chu L., Kogan Y., Chaga O., Goltsman E., Bernal A., Larsen N., D'Souza M.,
RA Walunas T., Pusch G., Haselkorn R., Fonstein M., Kyrpides N., Overbeek R.;
RT "Genome sequence and analysis of the oral bacterium Fusobacterium nucleatum
RT strain ATCC 25586.";
RL J. Bacteriol. 184:2005-2018(2002).
RN [2] {ECO:0000313|Proteomes:UP000241660}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25586 {ECO:0000313|Proteomes:UP000241660};
RX PubMed=29976645; DOI=10.1128/msphere.00269-18;
RA Todd S.M., Settlage R.E., Lahmers K.K., Slade D.J.;
RT "Fusobacterium Genomics Using MinION and Illumina Sequencing Enables Genome
RT Completion and Correction.";
RL MSphere 3:0-0(2018).
RN [3] {ECO:0000313|EMBL:AVQ15712.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 25586 {ECO:0000313|EMBL:AVQ15712.1};
RA Slade D.J., Lahmers K.;
RT "Complete Fusobacterium genomes using hybrid Minion sequencing.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Carbohydrate degradation. {ECO:0000256|ARBA:ARBA00004921}.
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DR EMBL; AE009951; AAL95610.1; -; Genomic_DNA.
DR EMBL; CP028101; AVQ15712.1; -; Genomic_DNA.
DR RefSeq; NP_604311.1; NC_003454.1.
DR RefSeq; WP_011017137.1; NZ_CP028101.1.
DR AlphaFoldDB; Q8RDT5; -.
DR FunCoup; Q8RDT5; 49.
DR STRING; 190304.FN1417; -.
DR PaxDb; 190304-FN1417; -.
DR EnsemblBacteria; AAL95610; AAL95610; FN1417.
DR GeneID; 79784386; -.
DR KEGG; fnu:FN1417; -.
DR PATRIC; fig|190304.8.peg.1978; -.
DR eggNOG; COG0235; Bacteria.
DR HOGENOM; CLU_006033_3_0_0; -.
DR InParanoid; Q8RDT5; -.
DR BioCyc; FNUC190304:G1FZS-1987-MONOMER; -.
DR Proteomes; UP000241660; Chromosome.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0016832; F:aldehyde-lyase activity; IBA:GO_Central.
DR GO; GO:0008738; F:L-fuculose-phosphate aldolase activity; IEA:UniProtKB-EC.
DR GO; GO:0046914; F:transition metal ion binding; IEA:UniProtKB-ARBA.
DR GO; GO:0019323; P:pentose catabolic process; IBA:GO_Central.
DR FunFam; 3.40.225.10:FF:000005; L-fuculose phosphate aldolase; 1.
DR Gene3D; 3.40.225.10; Class II aldolase/adducin N-terminal domain; 1.
DR InterPro; IPR050197; Aldolase_class_II_sugar_metab.
DR InterPro; IPR001303; Aldolase_II/adducin_N.
DR InterPro; IPR036409; Aldolase_II/adducin_N_sf.
DR NCBIfam; NF005302; PRK06833.1; 1.
DR PANTHER; PTHR22789:SF0; 3-OXO-TETRONATE 4-PHOSPHATE DECARBOXYLASE-RELATED; 1.
DR PANTHER; PTHR22789; FUCULOSE PHOSPHATE ALDOLASE; 1.
DR Pfam; PF00596; Aldolase_II; 1.
DR SMART; SM01007; Aldolase_II; 1.
DR SUPFAM; SSF53639; AraD/HMP-PK domain-like; 1.
PE 4: Predicted;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000313|EMBL:AAL95610.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000241660}.
FT DOMAIN 8..186
FT /note="Class II aldolase/adducin N-terminal"
FT /evidence="ECO:0000259|SMART:SM01007"
SQ SEQUENCE 222 AA; 24717 MW; 6944AF563D7114D0 CRC64;
MLLENERKEI IVYGKKMITD GLTRGTGGNI SICDAEQKLM AITPSGIDYF KLTPEDIVII
DVETGKIVDS NRVPSSESDM HRIFYKYRKG VFSVVHTHSK YATAISCTDI EGLPAINYLL
AVAGTDVPCA EYATYGTIKL AKNAFKAMED KKAVLLSNHG MIAIGKNLAE AYNIAENVEF
CSELFCISKS IGSPKILSKE EMLNMIERFK DYGKRIEEHE EI
//
