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Database: UniProt
Entry: Q9R8E4
LinkDB: Q9R8E4
Original site: Q9R8E4 
ID   Q9R8E4_ECOLX            Unreviewed;       203 AA.
AC   Q9R8E4;
DT   01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2000, sequence version 1.
DT   19-JAN-2022, entry version 106.
DE   SubName: Full=IpaB/EvcA family protein {ECO:0000313|EMBL:ACU09452.1};
DE   SubName: Full=L0028 {ECO:0000313|EMBL:AAC31507.1};
DE   SubName: Full=Mitochondria associated protein {ECO:0000313|EMBL:ACG59682.1};
DE   SubName: Full=T3SS effector protein Map {ECO:0000313|EMBL:API11945.1};
DE   SubName: Full=Type III effector protein {ECO:0000313|EMBL:STI62681.1};
DE   SubName: Full=Type III secretion system LEE effector Map (Rho guanine exchange factor) {ECO:0000313|EMBL:QCL45817.1};
GN   Name=map {ECO:0000313|EMBL:QCL45817.1};
GN   ORFNames=BFL24_25035 {ECO:0000313|EMBL:API11945.1}, C9E67_00645
GN   {ECO:0000313|EMBL:QCL45817.1}, DAH23_17530
GN   {ECO:0000313|EMBL:TGG37766.1}, DAH24_18265
GN   {ECO:0000313|EMBL:TGG11219.1}, DAH25_18520
GN   {ECO:0000313|EMBL:TGJ90994.1}, DAH26_16365
GN   {ECO:0000313|EMBL:TGG24907.1}, DAH42_14080
GN   {ECO:0000313|EMBL:TGF41618.1}, DAH43_15830
GN   {ECO:0000313|EMBL:TGF19866.1}, DAH45_16210
GN   {ECO:0000313|EMBL:TGF27237.1}, DAH46_15050
GN   {ECO:0000313|EMBL:TGF10884.1}, DAH47_16705
GN   {ECO:0000313|EMBL:TGF27081.1}, DAH48_16210
GN   {ECO:0000313|EMBL:TGF04692.1}, DAH49_17290
GN   {ECO:0000313|EMBL:TGF12050.1}, NCTC13127_00329
GN   {ECO:0000313|EMBL:STI62681.1};
OS   Escherichia coli.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562 {ECO:0000313|EMBL:AAC31507.1};
RN   [1] {ECO:0000313|EMBL:AAC31507.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC43895 {ECO:0000313|EMBL:AAC31507.1}, and EDL933
RC   {ECO:0000313|EMBL:AAC31507.1};
RX   PubMed=9673266;
RA   Perna N.T., Mayhew G.F., Posfai G., Elliott S., Donnenberg M.S.,
RA   Kaper J.B., Blattner F.R.;
RT   "Molecular evolution of a pathogenicity island from enterohemorrhagic
RT   Escherichia coli O157:H7.";
RL   Infect. Immun. 66:3810-3817(1998).
RN   [2] {ECO:0000313|EMBL:ACG59682.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=EDS-58 {ECO:0000313|EMBL:ACG59682.1};
RA   Zhang Y.;
RL   Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0007829|PDB:3GCG}
RP   X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) OF 37-203.
RX   PubMed=19620963; DOI=10.1038/nsmb.1647;
RA   Huang Z., Sutton S.E., Wallenfang A.J., Orchard R.C., Wu X., Feng Y.,
RA   Chai J., Alto N.M.;
RT   "Structural insights into host GTPase isoform selection by a family of
RT   bacterial GEF mimics.";
RL   Nat. Struct. Mol. Biol. 16:853-860(2009).
RN   [4] {ECO:0000313|EMBL:ACU09452.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=71074 {ECO:0000313|EMBL:ACU09452.1};
RA   Zhang Y., Golds G., John S.J., Laing C.R., Gannon V.P.J.;
RL   Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN   [5] {ECO:0000313|EMBL:API11945.1, ECO:0000313|Proteomes:UP000183146}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=319 {ECO:0000313|EMBL:API11945.1,
RC   ECO:0000313|Proteomes:UP000183146};
RA   Shaaban S., Cowley L., McAteer S.P., Jenkins C., Dallman T.J., Bono J.L.,
RA   Gally D.L.;
RT   "Evolution of a zoonotic pathogen: investigating prophage diversity in
RT   enterohaemorrhagic E. coli O157 by long-read sequencing.";
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
RN   [6] {ECO:0000313|Proteomes:UP000297296, ECO:0000313|Proteomes:UP000297363}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C287 {ECO:0000313|EMBL:TGG37766.1,
RC   ECO:0000313|Proteomes:UP000298414}, C304 {ECO:0000313|EMBL:TGG11219.1,
RC   ECO:0000313|Proteomes:UP000297618}, C305 {ECO:0000313|EMBL:TGJ90994.1,
RC   ECO:0000313|Proteomes:UP000298391}, C306 {ECO:0000313|EMBL:TGG24907.1,
RC   ECO:0000313|Proteomes:UP000297363}, MFS 13
RC   {ECO:0000313|EMBL:TGF41618.1, ECO:0000313|Proteomes:UP000298485}, MFS
RC   18 {ECO:0000313|EMBL:TGF19866.1, ECO:0000313|Proteomes:UP000297852},
RC   MFS 25 {ECO:0000313|EMBL:TGF27237.1,
RC   ECO:0000313|Proteomes:UP000297479}, MFS 26
RC   {ECO:0000313|EMBL:TGF10884.1, ECO:0000313|Proteomes:UP000297296}, MFS
RC   4 {ECO:0000313|EMBL:TGF27081.1, ECO:0000313|Proteomes:UP000298487},
RC   MFS 5 {ECO:0000313|EMBL:TGF04692.1,
RC   ECO:0000313|Proteomes:UP000297850}, and MFS 9
RC   {ECO:0000313|EMBL:TGF12050.1, ECO:0000313|Proteomes:UP000298047};
RA   Baranzoni G.M., Fratamico P.M., Kim G.-H., Funk J.A., Manning S.D.,
RA   Bosilevac J.M.;
RT   "Whole genome sequences of Shiga Toxin-producing Escherichia coli isolated
RT   from swine and other sources.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [7] {ECO:0000313|EMBL:QCL45817.1, ECO:0000313|Proteomes:UP000298553}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=143 {ECO:0000313|EMBL:QCL45817.1,
RC   ECO:0000313|Proteomes:UP000298553};
RA   Bono J.L., Arthur T.M.;
RT   "WGA of Escherichia coli O157:H7: comparison of multiple isolates.";
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [8] {ECO:0000313|EMBL:STI62681.1, ECO:0000313|Proteomes:UP000254180}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC13127 {ECO:0000313|EMBL:STI62681.1,
RC   ECO:0000313|Proteomes:UP000254180};
RG   Pathogen Informatics;
RA   Doyle S.;
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- INTERACTION:
CC       Q9R8E4; P60953-2: CDC42; Xeno; NbExp=5; IntAct=EBI-15794593, EBI-287394;
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DR   EMBL; AF071034; AAC31507.1; -; Genomic_DNA.
DR   EMBL; EU871627; ACG59682.1; -; Genomic_DNA.
DR   EMBL; GQ338312; ACU09452.1; -; Genomic_DNA.
DR   EMBL; CP018241; API11945.1; -; Genomic_DNA.
DR   EMBL; CP028607; QCL45817.1; -; Genomic_DNA.
DR   EMBL; UGCM01000003; STI62681.1; -; Genomic_DNA.
DR   EMBL; QAFT01000013; TGF04692.1; -; Genomic_DNA.
DR   EMBL; QAFR01000012; TGF10884.1; -; Genomic_DNA.
DR   EMBL; QAFU01000013; TGF12050.1; -; Genomic_DNA.
DR   EMBL; QAFO01000013; TGF19866.1; -; Genomic_DNA.
DR   EMBL; QAFS01000014; TGF27081.1; -; Genomic_DNA.
DR   EMBL; QAFQ01000013; TGF27237.1; -; Genomic_DNA.
DR   EMBL; QAFN01000011; TGF41618.1; -; Genomic_DNA.
DR   EMBL; QAEV01000013; TGG11219.1; -; Genomic_DNA.
DR   EMBL; QAEX01000012; TGG24907.1; -; Genomic_DNA.
DR   EMBL; QAEU01000013; TGG37766.1; -; Genomic_DNA.
DR   EMBL; QAEW01000013; TGJ90994.1; -; Genomic_DNA.
DR   PIR; B91199; B91199.
DR   PIR; F86045; F86045.
DR   RefSeq; WP_000492638.1; NZ_WJRH01000013.1.
DR   PDB; 3GCG; X-ray; 2.30 A; B=37-203.
DR   PDBsum; 3GCG; -.
DR   DIP; DIP-48540N; -.
DR   IntAct; Q9R8E4; 1.
DR   EnsemblBacteria; AMW43469; AMW43469; ARC77_15010.
DR   EnsemblBacteria; APA39888; APA39888; AU473_02850.
DR   EnsemblBacteria; CTT81500; CTT81500; ERS085383_02502.
DR   EnsemblBacteria; CTV81086; CTV81086; ERS085404_04285.
DR   EnsemblBacteria; OOC77435; OOC77435; BWP17_19275.
DR   EnsemblBacteria; OWC16445; OWC16445; A8G17_12590.
DR   EnsemblBacteria; PAU11010; PAU11010; BTQ04_20915.
DR   EnsemblBacteria; PJG34646; PJG34646; CVH05_05515.
DR   EnsemblBacteria; QCL45817; QCL45817; C9E67_00645.
DR   EnsemblBacteria; RCP40747; RCP40747; A6581_10245.
DR   EnsemblBacteria; RFQ84566; RFQ84566; CRE06_16840.
DR   EnsemblBacteria; STI62681; STI62681; NCTC13127_00329.
DR   EnsemblBacteria; STK11011; STK11011; NCTC9701_00178.
DR   PATRIC; fig|562.7074.peg.2948; -.
DR   Proteomes; UP000183146; Chromosome.
DR   Proteomes; UP000254180; Unassembled WGS sequence.
DR   Proteomes; UP000297296; Unassembled WGS sequence.
DR   Proteomes; UP000297363; Unassembled WGS sequence.
DR   Proteomes; UP000297479; Unassembled WGS sequence.
DR   Proteomes; UP000297618; Unassembled WGS sequence.
DR   Proteomes; UP000297850; Unassembled WGS sequence.
DR   Proteomes; UP000297852; Unassembled WGS sequence.
DR   Proteomes; UP000298047; Unassembled WGS sequence.
DR   Proteomes; UP000298391; Unassembled WGS sequence.
DR   Proteomes; UP000298414; Unassembled WGS sequence.
DR   Proteomes; UP000298485; Unassembled WGS sequence.
DR   Proteomes; UP000298487; Unassembled WGS sequence.
DR   Proteomes; UP000298553; Chromosome.
DR   InterPro; IPR004959; Bac_effector_IpgB-like.
DR   Pfam; PF03278; IpaB_EvcA; 1.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0007829|PDB:3GCG}.
SQ   SEQUENCE   203 AA;  22924 MW;  4BEDDA6625BD8089 CRC64;
     MFSPMTMAGR SLVQATAQTL KPAVTRAAMQ AGTGATGMRF MPVQSNFVIN HGKLTNQLLQ
     AVAKQTRNGD TQQWFQQEQT TYISRTVNRT LDDYCRSNNS VISKETKGHI FRAVENALQQ
     PLDMNGAQSS IGHFLQSNKY FNQKVDEQCG KRVDPITRFN TQTKMIEQVS QEIFERNFSG
     FKVSEIKAIT QNAILEHVQD TRL
//
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