ID R8BE27_PHAM7 Unreviewed; 561 AA.
AC R8BE27;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 28-JAN-2026, entry version 43.
DE SubName: Full=Putative sphingosine kinase protein {ECO:0000313|EMBL:EON97525.1};
GN ORFNames=UCRPA7_7104 {ECO:0000313|EMBL:EON97525.1};
OS Phaeoacremonium minimum (strain UCR-PA7) (Esca disease fungus) (Togninia
OS minima).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Togniniales; Togniniaceae; Phaeoacremonium.
OX NCBI_TaxID=1286976 {ECO:0000313|EMBL:EON97525.1, ECO:0000313|Proteomes:UP000014074};
RN [1] {ECO:0000313|Proteomes:UP000014074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UCR-PA7 {ECO:0000313|Proteomes:UP000014074};
RX PubMed=23814032; DOI=10.1128/genomea.00390-13;
RA Blanco-Ulate B., Rolshausen P., Cantu D.;
RT "Draft genome sequence of the ascomycete Phaeoacremonium aleophilum strain
RT UCR-PA7, a causal agent of the esca disease complex in grapevines.";
RL Genome Announc. 1:E0039013-E0039013(2013).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB933264; EON97525.1; -; Genomic_DNA.
DR RefSeq; XP_007917829.1; XM_007919638.1.
DR AlphaFoldDB; R8BE27; -.
DR GeneID; 19327831; -.
DR KEGG; tmn:UCRPA7_7104; -.
DR eggNOG; KOG1116; Eukaryota.
DR HOGENOM; CLU_013399_0_1_1; -.
DR OrthoDB; 3853857at2759; -.
DR Proteomes; UP000014074; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR GO; GO:0016020; C:membrane; IEA:TreeGrafter.
DR GO; GO:0001727; F:lipid kinase activity; IEA:TreeGrafter.
DR GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:UniProtKB-ARBA.
DR GO; GO:0046512; P:sphingosine biosynthetic process; IEA:TreeGrafter.
DR Gene3D; 2.60.200.40; -; 1.
DR Gene3D; 3.40.50.10330; Probable inorganic polyphosphate/atp-NAD kinase, domain 1; 1.
DR InterPro; IPR017438; ATP-NAD_kinase_N.
DR InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR InterPro; IPR055916; DUF7493.
DR InterPro; IPR050187; Lipid_Phosphate_FormReg.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR PANTHER; PTHR12358:SF31; ACYLGLYCEROL KINASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR12358; SPHINGOSINE KINASE; 1.
DR Pfam; PF00781; DAGK_cat; 1.
DR Pfam; PF24321; DUF7493; 1.
DR SMART; SM00046; DAGKc; 1.
DR SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
DR PROSITE; PS50146; DAGK; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:EON97525.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000014074};
KW Transferase {ECO:0000313|EMBL:EON97525.1}.
FT DOMAIN 157..296
FT /note="DAGKc"
FT /evidence="ECO:0000259|PROSITE:PS50146"
SQ SEQUENCE 561 AA; 61228 MW; 938F716394BDD8DE CRC64;
MASEAPVTAP LEPFPEAIQE SGAPQANGNG NATSQPVALT ETINLGRNVS LTLENDSLRV
QDKAGQKKSR TCGIDFSSDA STTRSIPLYN VLWAELSDDR QTLTVDFAEE TSKTRLRVSQ
LTYKTAPTAG AEHHSTPTPG IETWIEALLT RSYGPAARRK RAYVLVNPHA GPGGADKKWE
TQVRPIFAAA RMPMEVIETK YSGEAVELCQ KMDIDAFDIV VPCSGDGLPY ECFNGLGRRA
DARRALEKLA VCHIPCGSGN AMACNLYGTH RPSLAALAIV KGVPTPMDLV SITQGDRRTL
SFLSQSLGIV AESDLATESM RWMGETRFTV GFLVRLFQKK VYPCDIAVKL EIGHKEGVKG
HYKRERENSS TEALDKFSSS AVNLNGTRVR DESLAESEAT GSSNKEGLPP LKYGTINDKL
PEGWEVIPGE KMGNFYCGNM AYMAPDANFF SAALVNDGLM DLVCIDGNIS PMKSIELMLS
VESGHFFDNP LVAYRKVSAY RIIPKNQSDG YISIDGERVP FEPFQAEIHQ GLGKVLSKRG
GYEAPGPHNW DKVTVTERYM A
//
